Compile Data Set for Download or QSAR
maximum 50k data
Found 4525 of ic50 data for polymerid = 2965,4873
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM640384((S)-(2-Chloro-6-fluorophenyl)(3-(3,5-difluoropheny...)
Affinity DataIC50:  0.00200nMAssay Description:The assay consists of combining endogenously expressed MGL from HeLa cells with test compounds, adding [glycerol-1,3-3H]-oleyl glycerol, incubating f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50582221(CHEMBL5090028 | US11708359, Example 60)
Affinity DataIC50:  0.00700nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50582221(CHEMBL5090028 | US11708359, Example 60)
Affinity DataIC50:  0.00720nMAssay Description:Inhibition of human MGL expressed in human HeLa cells assessed as amount of cleaved glycerol measured after 1 hrs by flow through assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM581474((2s,4s)-2-(2-(3-(tert-Butyl)phenyl)-7-azaspiro[3.5...)
Affinity DataIC50:  0.0140nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM609871((rac)-(2s,4s)-2-(6-(4-(tert-Butyl)phenyl)-3-azabic...)
Affinity DataIC50:  0.0190nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50582222(CHEMBL5074982 | US11708359, Example 71)
Affinity DataIC50:  0.0240nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50582222(CHEMBL5074982 | US11708359, Example 71)
Affinity DataIC50:  0.0240nMAssay Description:Inhibition of human MGL expressed in human HeLa cells assessed as amount of cleaved glycerol measured after 1 hrs by flow through assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM581599((2r,4s)-2-(2-(5-(tert-Butyl)-2-methylphenyl)-7-aza...)
Affinity DataIC50:  0.0270nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50552710(CHEMBL4749516)
Affinity DataIC50:  0.0300nMAssay Description:Inhibition of MAGL (unknown origin) using 2-AG as substrate incubated for 15 mins followed by substrate addition and measured after 30 mins by mass s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM609880((rac)-(2s,4s)-2-(6-(4-(1-Methylcyclopropyl)phenyl)...)
Affinity DataIC50:  0.0340nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM581624((rac)-(2s,4s)-2-(2-(4-(Trifluoromethyl)phenyl)-8-a...)
Affinity DataIC50:  0.0390nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50552709(CHEMBL4759880)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of MAGL (unknown origin) using 2-AG as substrate incubated for 15 mins followed by substrate addition and measured after 30 mins by mass s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM581678((2s,4S)-N-((1s,3S)-3-(4-Isopropylphenyl)cyclobutyl...)
Affinity DataIC50:  0.0400nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM581678((2s,4S)-N-((1s,3S)-3-(4-Isopropylphenyl)cyclobutyl...)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of human MAGL expressed in HeLa cells using [glycerol-1, 3-3H]-oleoyl glycerol as substrate incubated for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50552711(CHEMBL4785835)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of MAGL (unknown origin) using 2-AG as substrate incubated for 15 mins followed by substrate addition and measured after 30 mins by mass s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM581534((2s,4s)-2-[2-(3-Isopropylphenyl)-7-azaspiro[3.5]no...)
Affinity DataIC50:  0.0410nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM581597((2s,4s)-2-[2-(2,4-Dimethylphenyl)-7-azaspiro[3.5]n...)
Affinity DataIC50:  0.0480nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50552713(CHEMBL4745872)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of MAGL (unknown origin) using 2-AG as substrate incubated for 15 mins followed by substrate addition and measured after 30 mins by mass s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM609878((rac)-(2s,4s)-2-(6-(3-Chloro-4-methylphenyl)-3- az...)
Affinity DataIC50:  0.0750nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM581596((2r,4s)-2-(2-(3-(tert-Butyl)phenyl)-7-azaspiro[3.5...)
Affinity DataIC50:  0.0820nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM581635((rac)-(2s,4s)-2-(6-(3-(tert-Butyl)phenyl)-2-azaspi...)
Affinity DataIC50:  0.0860nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM581518((2s,4s)-2-[2-(3-Cyclopropylphenyl)-7-azaspiro[3.5]...)
Affinity DataIC50:  0.0880nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM581594((2s,4s)-2-[2-[3-(Trifluoromethoxy)phenyl]-7-azaspi...)
Affinity DataIC50:  0.0940nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM581601((2r,4s)-2-(2-(6-(tert-Butyl)pyridin-2-yl)-7-azaspi...)
Affinity DataIC50:  0.0950nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM581650((2s,4s)-2-(6-(3-(tert-Butyl)phenyl)-2-azaspiro[3.3...)
Affinity DataIC50:  0.0970nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM630876((7-((3,6-Dimethyl-5-(trifluoromethyl)pyridin-2-yl)...)
Affinity DataIC50:  0.100nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM581631((2s,4R*)-2-((S*)-6-(4-(Trifluoromethyl)phenyl)-2-a...)
Affinity DataIC50:  0.100nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50552712(CHEMBL4749293)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of MAGL (unknown origin) using 2-AG as substrate incubated for 15 mins followed by substrate addition and measured after 30 mins by mass s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM581648((rac)-(2s,4s)-2-(6-(4-Isopropylphenyl)-2-azaspiro[...)
Affinity DataIC50:  0.100nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50552708(CHEMBL4756662)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of MAGL (unknown origin) using 2-AG as substrate incubated for 15 mins followed by substrate addition and measured after 30 mins by mass s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM581642((rac)-(2s,4s)-2-(2-(3-(tert-Butyl)phenyl)-8-azaspi...)
Affinity DataIC50:  0.100nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM581595((2s,4s)-2-[2-(2,3-Dimethylphenyl)-7-azaspiro[3.5]n...)
Affinity DataIC50:  0.110nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM581643((rac)-(2s,4s)-2-(2-(4-(tert-Butyl)phenyl)-8-azaspi...)
Affinity DataIC50:  0.110nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM581634((rac)-(2s,4s)-2-(6-(4-(tert-Butyl)phenyl)-2-azaspi...)
Affinity DataIC50:  0.110nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM597443((4-Fluoropyrazolo[1,5-a]pyridin-3-yl)((5R,9S)-2-me...)
Affinity DataIC50:  0.140nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM581646((rac)-(2s,4s)-2-(6-(3-Isopropylphenyl)-2-azaspiro[...)
Affinity DataIC50:  0.170nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM597214((4-Bromoquinolin-6-yl)((5R,9S)-3-(3,5-difluorophen...)
Affinity DataIC50:  0.180nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50250848(CHEMBL4059676)
Affinity DataIC50:  0.180nMAssay Description:Inhibition of human recombinant MAGL using 7-HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50250859(CHEMBL4097203)
Affinity DataIC50:  0.180nMAssay Description:Inhibition of human recombinant MAGL using 7-HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM630668(((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(7-(2-methyl...)
Affinity DataIC50:  0.200nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM626948((2s,4s)-2-(4-(4-(tert-Butyl)phenyl)piperidine-1-ca...)
Affinity DataIC50:  0.200nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM626965((racemic)-(2s,4S)-2-((3R,4R)-4-(4-(tert-Butyl)phen...)
Affinity DataIC50:  0.200nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM581668((2s,4S)-N-((1s,3S)-3-(4-(tert-Butyl)phenyl)cyclobu...)
Affinity DataIC50:  0.200nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM597927(US11608347, Example 55 | [(7R,9aR)-7-(3-chloro-4- ...)
Affinity DataIC50:  0.200nMAssay Description:In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM581668((2s,4S)-N-((1s,3S)-3-(4-(tert-Butyl)phenyl)cyclobu...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human MAGL expressed in HeLa cells using [glycerol-1, 3-3H]-oleoyl glycerol as substrate incubated for 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM626988((2s,4R*)-2-((2S*,4R*)-4-(4-(tert-Butyl)phenyl)-2-m...)
Affinity DataIC50:  0.200nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM609885((rac)-(2s,4s)-2-(6-(4-Isopropylphenyl)-3-azabicycl...)
Affinity DataIC50:  0.210nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM581658((2s,4s)-2-(6-(3-Cyclobutylphenyl)-2-azaspiro[3.3]h...)
Affinity DataIC50:  0.210nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50065646(CHEMBL3087181)
Affinity DataIC50:  0.214nMAssay Description:Inhibition of rat MAGLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM630869((7-((6-Ethoxy-5-(trifluoromethyl)pyridin-2-yl)oxy)...)
Affinity DataIC50:  0.220nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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