Affinity DataIC50: 0.200nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Displacement of [3H]-5-HT binding from cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cells.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition affinity against 5-HT-1B receptor in rat frontal cortex using radio binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.501nMAssay Description:Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataIC50: 0.930nMAssay Description:Inhibition affinity against 5-HT-1B receptor in rat frontal cortex using radio binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition affinity against 5-HT-1B receptor in rat frontal cortex using radio binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]-5-HT binding from cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cells.More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]-5-HT binding from the cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Binding affinity to human cloned 5-hydroxytryptamine 1B receptor in CHO cells by [3H]-5-HT binding displacement.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1B receptor in rat frontal cortex using [125I]-iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition affinity against 5-HT-1B receptor in rat frontal cortex using radio binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition affinity against 5-HT-1B receptor in rat frontal cortex using radio binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1B receptor in rat frontal cortex using [125I]-iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Displacement of [3H]-5-HT binding from cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cells.More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Displacement of [3H]-5-HT binding from the cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Displacement of specific [3H]-5-HT binding to cloned human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Displacement of [3H]-5-HT binding to cloned 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HT as the radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Displacement of [3H]-5-HT binding from the cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of radiolabeled [3H]-5-HT ligand binding to 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Displacement of [125I]CYP from rat cerebral cortex 5HT1B receptor measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Displacement of [125I]CYP from rat cerebral cortex 5-HT1B receptor in the presence of isoproternolMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Binding affinity of the compound against 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HT as the radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Displacement of specific [3H]-5-HT binding to cloned human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.20nMAssay Description:Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 6.20nMAssay Description:Displacement of [3H]-5-HT binding to cloned 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition affinity against 5-HT-1B receptor in rat frontal cortex using radio binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataIC50: 7.30nMAssay Description:Inhibition affinity against 5-HT-1B receptor in rat frontal cortex using radio binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.40nMAssay Description:Displacement of [3H]-5-HT binding from cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cells.More data for this Ligand-Target Pair
Affinity DataIC50: 8.10nMAssay Description:Displacement of [3H]-5-HT from human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Displacement of [3H]-5-HT binding to cloned 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Displacement of [3H]-5-HT binding to cloned 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:The compound was evaluated for its ability to displace [3H]5-HT from 5-hydroxytryptamine 1B receptor in cellular brain membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 9.30nMAssay Description:Displacement of [3H]-5-HT binding to cloned 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:Displacement of [3H]-5-HT binding from cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cells.More data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]-5-HT binding to cloned 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Binding affinity at cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cells by [3H]-5-HT displacement.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition affinity against 5-HT-1B receptor in rat frontal cortex using radio binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human 5HT1B expressed in CHO cells by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]-5-HT from human 5HT-1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]-5-HT binding from cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cells.More data for this Ligand-Target Pair