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Found 24 of ic50 data for polymerid = 4425,4885
TargetMethionine aminopeptidase 2(Mus musculus (Mouse))
Eli Lilly

US Patent
LigandPNGBDBM468977(1-[2-[(3R,5S,6R)-5-Aamino- 6-(2,5- difluorophenyl)...)
Affinity DataIC50:  10.6nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Mus musculus (Mouse))
Eli Lilly

US Patent
LigandPNGBDBM468975(1-[2-[(3R,5S,6R)-5-Amino-6- (2,5- difluorophenyl)t...)
Affinity DataIC50:  12.8nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Mus musculus (Mouse))
Eli Lilly

US Patent
LigandPNGBDBM468957(1-[2-[(3R,5S,6R)-5-Amino-6-(2,5-difluorophenyl)tet...)
Affinity DataIC50:  21.9nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Mus musculus (Mouse))
Eli Lilly

US Patent
LigandPNGBDBM468978(1-[1-[(3R,5S,6R)-5-Amino-6- (2,5- difluorophenyl)t...)
Affinity DataIC50:  29.2nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Mus musculus (Mouse))
Eli Lilly

US Patent
LigandPNGBDBM468979(1-[1-[(3R,5S,6R)-5-Amino- 6-(2,5- difluorophenyl)t...)
Affinity DataIC50:  30.5nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Mus musculus (Mouse))
Eli Lilly

US Patent
LigandPNGBDBM468976((3S)-1-[1-[(3R,5S,6R)-5-Amino-6-(2,5-difluoropheny...)
Affinity DataIC50:  32.1nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Mus musculus (Mouse))
Eli Lilly

US Patent
LigandPNGBDBM468958(1-[2-[(3R,5S,6R)-5-Amino- 6-(2,5- difluorophenyl)t...)
Affinity DataIC50:  33.6nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Mus musculus (Mouse))
Eli Lilly

US Patent
LigandPNGBDBM468964(1-[1-[(3R,5S,6R)-5-Amino-6-(2,5-difluorophenyl)tet...)
Affinity DataIC50:  36.8nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Mus musculus (Mouse))
Eli Lilly

US Patent
LigandPNGBDBM50547191(CHEMBL4746468)
Affinity DataIC50:  40nMAssay Description:Inhibition of MetAP2 in mouse B cells assessed as reduction in IgG secretionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMethionine aminopeptidase 2(Mus musculus (Mouse))
Eli Lilly

US Patent
LigandPNGBDBM468972((3S)-1-[2-[(3R,5S,6R)-5-Amino-6-(2,5-difluoropheny...)
Affinity DataIC50:  48nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Mus musculus (Mouse))
Eli Lilly

US Patent
LigandPNGBDBM468980(1-[1-[(3R,5S,6R)-5-Amino- 6-(2,5- difluorophenyl)t...)
Affinity DataIC50:  60.3nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Mus musculus (Mouse))
Eli Lilly

US Patent
LigandPNGBDBM468961((3S)-1-[6-[4-[(3S,5S,6R)-5-Amino-6-(2,5-difluoroph...)
Affinity DataIC50:  80.2nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Mus musculus (Mouse))
Eli Lilly

US Patent
LigandPNGBDBM468974(1-[2-[(3R,5S,6R)-5-Amino-6- (2,5- difluorophenyl)t...)
Affinity DataIC50:  94.7nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Mus musculus (Mouse))
Eli Lilly

US Patent
LigandPNGBDBM468959(1-[2-[4-[(3R,5S,6R)-5-Amino-6-(2,5-difluorophenyl)...)
Affinity DataIC50:  103nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Mus musculus (Mouse))
Eli Lilly

US Patent
LigandPNGBDBM468960(1-[2-[4-[(3R,5S,6R)-5- Amino-6-(2,5- difluoropheny...)
Affinity DataIC50:  111nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Mus musculus (Mouse))
Eli Lilly

US Patent
LigandPNGBDBM468963(1-[1-[(3R,5S,6R)-5-Amino-6-(2,5-difluorophenyl)tet...)
Affinity DataIC50:  123nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Mus musculus (Mouse))
Eli Lilly

US Patent
LigandPNGBDBM468973(1-[2-[(3R,5S,6R)-5-Amino-6- (2,5- difluorophenyl)t...)
Affinity DataIC50:  154nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Mus musculus (Mouse))
Eli Lilly

US Patent
LigandPNGBDBM468981((3S)-1-[2-[1-[(3R,5S,6R)-5-Amino-6-(2,5-difluoroph...)
Affinity DataIC50:  283nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Plasmodium falciparum)
Johns Hopkins School Of Medicine

LigandPNGBDBM17446((3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-m...)
Affinity DataIC50:  2.00E+3nMAssay Description:Enzyme affinity assay using Fumarranol analogs with plasmodium falciparum methionine aminopeptidases (PfMetAPs).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Plasmodium falciparum)
Johns Hopkins School Of Medicine

LigandPNGBDBM81354(Fumarranol Analog, 9)
Affinity DataIC50: >5.00E+5nMAssay Description:Enzyme affinity assay using Fumarranol analogs with plasmodium falciparum methionine aminopeptidases (PfMetAPs).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Plasmodium falciparum)
Johns Hopkins School Of Medicine

LigandPNGBDBM50194623((1S,5S,6R,E)-5-(hydroxymethyl)-1-methoxy-6-(6-meth...)
Affinity DataIC50: >5.00E+5nMAssay Description:Enzyme affinity assay using Fumarranol analogs with plasmodium falciparum methionine aminopeptidases (PfMetAPs).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Plasmodium falciparum)
Johns Hopkins School Of Medicine

LigandPNGBDBM50194621(6S-(1'R,2'R-1',5'-dimethyl-1',2'-oxiranyl-4'-hexen...)
Affinity DataIC50: >5.00E+5nMAssay Description:Enzyme affinity assay using Fumarranol analogs with plasmodium falciparum methionine aminopeptidases (PfMetAPs).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Plasmodium falciparum)
Johns Hopkins School Of Medicine

LigandPNGBDBM81353(Fumarranol Analog, 6)
Affinity DataIC50: >5.00E+5nMAssay Description:Enzyme affinity assay using Fumarranol analogs with plasmodium falciparum methionine aminopeptidases (PfMetAPs).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Plasmodium falciparum)
Johns Hopkins School Of Medicine

LigandPNGBDBM81355(Fumarranol Analog, 10)
Affinity DataIC50: >5.00E+5nMAssay Description:Enzyme affinity assay using Fumarranol analogs with plasmodium falciparum methionine aminopeptidases (PfMetAPs).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed