Compile Data Set for Download or QSAR
maximum 50k data
Found 162 of ic50 data for polymerid = 50001156
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462683(CHEMBL4247249)
Affinity DataIC50:  7nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50450346(CHEMBL300883)
Affinity DataIC50:  10nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285443(Benzooxazol-2-yl-[5-(4,5-diphenyl-1H-imidazol-2-yl...)
Affinity DataIC50:  20nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462702(CHEMBL4241747)
Affinity DataIC50:  30nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462684(CHEMBL4243015)
Affinity DataIC50:  40nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462661(CHEMBL4240947)
Affinity DataIC50:  43nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462653(CHEMBL4245998)
Affinity DataIC50:  48nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285435(Benzooxazol-2-yl-{5-[4,5-bis-(4-dimethylamino-phen...)
Affinity DataIC50:  50nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462652(CHEMBL4248936)
Affinity DataIC50:  59nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50069900(2,6-diisopropylphenyl 2-(2,4,6-triisopropylphenyl)...)
Affinity DataIC50:  60nMAssay Description:Inhibition of ACAT1 in mouse IC21 cells in absence of BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50450357(CHEMBL48164)
Affinity DataIC50:  60nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50450361(CHEMBL300913)
Affinity DataIC50:  60nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285432(1N,1N-dimethyl-4-[2-{5-[4,5-di(4-dimethylaminophen...)
Affinity DataIC50:  60nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285447(CHEMBL53397 | {5-[4,5-Bis-(4-methoxy-phenyl)-1H-im...)
Affinity DataIC50:  70nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285420(Benzooxazol-2-yl-{5-[4,5-bis-(4-methoxy-phenyl)-1H...)
Affinity DataIC50:  70nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285434(Benzooxazol-2-yl-{5-[4,5-bis-(4-methoxy-phenyl)-1H...)
Affinity DataIC50:  80nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285442(Benzooxazol-2-yl-{5-[4,5-bis-(4-methoxy-phenyl)-1H...)
Affinity DataIC50:  80nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285444(1N,1N-dimethyl-4-{5-(4-dimethylaminophenyl)-2-[5-(...)
Affinity DataIC50:  80nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  90nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285430(Benzooxazol-2-yl-{5-[4,5-bis-(4-dimethylamino-phen...)
Affinity DataIC50:  90nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285427(Benzooxazol-2-yl-{5-[4,5-bis-(4-methoxy-phenyl)-1H...)
Affinity DataIC50:  90nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50450366(CHEMBL49265)
Affinity DataIC50:  90nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462670(CHEMBL4239138)
Affinity DataIC50:  100nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50450345(CHEMBL51643)
Affinity DataIC50:  100nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462706(CHEMBL4249263)
Affinity DataIC50:  100nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462703(CHEMBL4249787)
Affinity DataIC50:  100nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462677(CHEMBL4245984)
Affinity DataIC50:  180nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462682(CHEMBL4239248)
Affinity DataIC50:  180nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50450364(CHEMBL50171)
Affinity DataIC50:  190nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285419(2-{5-[4,5-di(4-methoxyphenyl)-1H-2-imidazolylsulfa...)
Affinity DataIC50:  200nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50287517(3-(2,6-Diisopropyl-phenyl)-1-(2-dodecyl-2H-tetrazo...)
Affinity DataIC50:  240nMAssay Description:Compound was tested for its ability to penetrate the cell wall and inhibit macrophage ACAT in cell culture using murine IC-21 macrophages (MAI)More data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285433(1N,1N-dimethyl-4-{5-(4-dimethylaminophenyl)-2-[5-(...)
Affinity DataIC50:  250nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462658(CHEMBL4238015)
Affinity DataIC50:  280nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462659(CHEMBL4248950)
Affinity DataIC50:  300nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462665(CHEMBL4248172)
Affinity DataIC50:  310nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50005944(2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...)
Affinity DataIC50:  310nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285428(1-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-yls...)
Affinity DataIC50:  320nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462680(CHEMBL4238030)
Affinity DataIC50:  350nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50450348(CHEMBL51282)
Affinity DataIC50:  370nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50005944(2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...)
Affinity DataIC50:  400nMAssay Description:Compound was tested for its ability to penetrate the cell wall and inhibit macrophage ACAT in cell culture using murine IC-21 macrophages (MAI)More data for this Ligand-Target Pair
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462671(CHEMBL4249719)
Affinity DataIC50:  400nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462657(CHEMBL4244680)
Affinity DataIC50:  410nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462660(CHEMBL4245518)
Affinity DataIC50:  410nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50450347(CHEMBL431940)
Affinity DataIC50:  450nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462679(CHEMBL4244693)
Affinity DataIC50:  460nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462708(CHEMBL4243773)
Affinity DataIC50:  470nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285425((1H-Benzoimidazol-2-yl)-{5-[4,5-bis-(4-methoxy-phe...)
Affinity DataIC50:  490nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285418(Benzooxazol-2-yl-ethyl-{5-[5-(4-methylsulfanyl-phe...)
Affinity DataIC50:  500nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285424(Benzooxazol-2-yl-{4-[4,5-bis-(4-methoxy-phenyl)-1H...)
Affinity DataIC50:  500nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Mus musculus)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462699(CHEMBL4245696)
Affinity DataIC50:  500nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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