TargetLanosterol synthase(Candida albicans (strain SC5314 / ATCC MYA-2876) (...)
Sinhgad College Of Pharmacy
Curated by ChEMBL
Sinhgad College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 0.220nMAssay Description:Inhibition of Candida albicans OSCMore data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:Compound was tested for inhibition of purified Oxidosqualene-lanosterol cyclase from Candida albicansMore data for this Ligand-Target Pair
Affinity DataIC50: >1nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Compound was tested for inhibition of purified Oxidosqualene-lanosterol cyclase from Candida albicansMore data for this Ligand-Target Pair
Affinity DataIC50: 2.88nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase from human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human liver microsome 2,3-OSC after 1 hr by Silica gel plate phosphor imagingMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase from human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of 2,3-oxidosqualene-lanosterol cyclase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
Affinity DataIC50: 3.47nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase from human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
Affinity DataIC50: 4.07nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase from human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Tested for Oxidosqualene-lanosterol cyclase inhibition in T. bruceiMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Tested for Oxidosqualene-lanosterol cyclase inhibition in P. cariniiMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human liver microsome 2,3-OSC after 1 hr by Silica gel plate phosphor imagingMore data for this Ligand-Target Pair
Affinity DataIC50: 5.37nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase from human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human liver microsome 2,3-OSC after 1 hr by Silica gel plate phosphor imagingMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of 2,3-oxidosqualene-lanosterol cyclase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6.20nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
Affinity DataIC50: 6.20nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human MB-COMT expressed in HEK293 cells using dopamine as substrate and SAM as cofactor preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
Affinity DataIC50: 6.46nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase from human liver microsomesMore data for this Ligand-Target Pair