Compile Data Set for Download or QSAR
maximum 50k data
Found 645 of ic50 data for polymerid = 50005991,9048
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092072(CHEMBL3582419 | US9296728, 14)
Affinity DataIC50:  7.60nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092069(CHEMBL3582422 | US9296728, 20)
Affinity DataIC50:  8nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092069(CHEMBL3582422 | US9296728, 20)
Affinity DataIC50:  8nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092072(CHEMBL3582419 | US9296728, 14)
Affinity DataIC50:  9nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092073(CHEMBL3582418 | US9296728, 13)
Affinity DataIC50:  9.5nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092058(CHEMBL3582408)
Affinity DataIC50:  10nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092068(CHEMBL3582423)
Affinity DataIC50:  11nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092071(CHEMBL3582420 | US9296728, 18)
Affinity DataIC50:  11nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092073(CHEMBL3582418 | US9296728, 13)
Affinity DataIC50:  12nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092071(CHEMBL3582420 | US9296728, 18)
Affinity DataIC50:  15nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM214697(US9296728, 19)
Affinity DataIC50:  19nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092070(CHEMBL3582421 | US9296728, 15)
Affinity DataIC50:  23nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092067(CHEMBL3582424 | US9296728, 16)
Affinity DataIC50:  25nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092065(CHEMBL3582426)
Affinity DataIC50:  25nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092057(CHEMBL3582409 | US9296728, 4)
Affinity DataIC50:  26nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092067(CHEMBL3582424 | US9296728, 16)
Affinity DataIC50:  29nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092076(CHEMBL3582415)
Affinity DataIC50:  30nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092057(CHEMBL3582409 | US9296728, 4)
Affinity DataIC50:  30nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092070(CHEMBL3582421 | US9296728, 15)
Affinity DataIC50:  34nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM214695(US9296728, 10)
Affinity DataIC50:  43nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM214702(US9296728, 25)
Affinity DataIC50:  48nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092066(CHEMBL3582425)
Affinity DataIC50:  48nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Vettore

US Patent
LigandPNGBDBM345287(2-[[1-[(2-Chlorophenyl)methyl]-5-[3- (cyclopropyl...)
Affinity DataIC50:  54.5nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Vettore

US Patent
LigandPNGBDBM356766(US10214492, Example 130)
Affinity DataIC50:  55nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Vettore

US Patent
LigandPNGBDBM546629(2-([1-[(2-Chlorophenyl)methyl]-5-(4- cyclopropoxyt...)
Affinity DataIC50:  55nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM214698(US9296728, 21)
Affinity DataIC50:  59nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092075(CHEMBL3582416 | US9296728, 11)
Affinity DataIC50:  64nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092018(CHEMBL3582410 | US9296728, 9)
Affinity DataIC50:  66nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50606661(CHEMBL5220706)
Affinity DataIC50:  66nMAssay Description:Inhibition of MCT1 in rat RBE4 cells assessed as reduction in [14C]lactate uptake measured after 15 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092059(CHEMBL3582407)
Affinity DataIC50:  70nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092075(CHEMBL3582416 | US9296728, 11)
Affinity DataIC50:  70nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092078(CHEMBL3582413 | US9296728, 7)
Affinity DataIC50:  88nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM214702(US9296728, 25)
Affinity DataIC50:  90nMAssay Description:Inhibition of MCT1 in rat brain endothelial 4 cells assessed as L-[14C]-Lactate Uptake after 15 mins by scintillation spectrometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM214696(US9296728, 17)
Affinity DataIC50:  91nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Vettore

US Patent
LigandPNGBDBM345295(1-[[1-[(2-Chlorophenyl)methyl]-5-(3- methoxypheny...)
Affinity DataIC50:  100nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092018(CHEMBL3582410 | US9296728, 9)
Affinity DataIC50:  100nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Vettore

US Patent
LigandPNGBDBM345271(1-[[5-(4-Chlorophenyl)-1-[(2- chlorophenyl)methyl...)
Affinity DataIC50:  100nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Vettore

US Patent
LigandPNGBDBM356738(US10214492, Example 108 | US11292767, Example 108)
Affinity DataIC50:  102nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Vettore

US Patent
LigandPNGBDBM356858(US10214492, Example 207 | US11292767, Example 207)
Affinity DataIC50:  102nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Vettore

US Patent
LigandPNGBDBM356768(US10214492, Example 132 | US11292767, Example 132)
Affinity DataIC50:  104nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Vettore

US Patent
LigandPNGBDBM22000(7-[(3-hydroxypropyl)sulfanyl]-2-methyl-4-(2-methyl...)
Affinity DataIC50:  105nMAssay Description:Inhibition of MCT1 (unknown origin) overexpressed in human MCF7 cells assessed as inhibition of transporter-mediated [14C]lactate transport after 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092078(CHEMBL3582413 | US9296728, 7)
Affinity DataIC50:  110nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM214705(US9296728, 29)
Affinity DataIC50:  110nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092074(CHEMBL3582417 | US9296728, 12)
Affinity DataIC50:  110nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Vettore

US Patent
LigandPNGBDBM50055506(CHEMBL3326270)
Affinity DataIC50:  116nMAssay Description:Inhibition of MCT1 (unknown origin) overexpressed in human MCF7 cells assessed as inhibition of transporter-mediated [14C]lactate transport after 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092017(CHEMBL3582411 | US9296728, 5)
Affinity DataIC50:  120nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM4345((2E)-2-cyano-3-[4-(dimethylamino)phenyl]prop-2-eno...)
Affinity DataIC50:  140nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092074(CHEMBL3582417 | US9296728, 12)
Affinity DataIC50:  140nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092017(CHEMBL3582411 | US9296728, 5)
Affinity DataIC50:  140nMAssay Description:Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM214701(US9296728, 24)
Affinity DataIC50:  150nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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