Compile Data Set for Download or QSAR
maximum 50k data
Found 9 of ic50 data for polymerid = 50006920
TargetDNA-3-methyladenine glycosylase(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM60996(5-[(3-carboxy-4-hydroxy-phenyl)-(3-carboxy-4-keto-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human purified MPG pre-incubated with compound for 10 mins followed by addition of 1,N6 ethenoadenine containing 32P-labeled duplex oli...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-3-methyladenine glycosylase(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM67690(1,4-bis[2-(2-hydroxyethylamino)ethylamino]-5,8-bis...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human purified MPG pre-incubated with compound for 10 mins followed by addition of 1,N6 ethenoadenine containing 32P-labeled duplex oli...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-3-methyladenine glycosylase(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopy...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human AAG using HXO2/Loop01 oligonucleotide as substrate incubated for 2 hrs by colorimetric based microplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-3-methyladenine glycosylase(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopy...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human purified MPG pre-incubated with compound for 10 mins followed by addition of 1,N6 ethenoadenine containing 32P-labeled duplex oli...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-3-methyladenine glycosylase(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM23223(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human purified MPG pre-incubated with compound for 10 mins followed by addition of 1,N6 ethenoadenine containing 32P-labeled duplex oli...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-3-methyladenine glycosylase(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopy...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human purified MPG binding to immobilized ethenoadenine containing 5'-TCGAGGATCCTGAGCTCGAGTCGACGXTCGCGAATTCTGCGGATCCAAGC-3' duplex olig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-3-methyladenine glycosylase(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopy...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of MPG in human A549 cell extracts at 50 to 300 uM using 1,N6 ethenoadenine containing 32P-labeled duplex oligonucleotide substrates by ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-3-methyladenine glycosylase(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50559764(CHEMBL4751946)
Affinity DataIC50:  1.57E+5nMAssay Description:Inhibition of human AAG using HXO2/Loop01 oligonucleotide as substrate incubated for 2 hrs by colorimetric based microplate assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA-3-methyladenine glycosylase(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopy...)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibition of MPG in human HeLa cell extracts at 50 to 300 uM using 1,N6 ethenoadenine containing 32P-labeled duplex oligonucleotide substrates by ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed