Compile Data Set for Download or QSAR
maximum 50k data
Found 186 of ic50 data for polymerid = 8286
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305863(3-(3-methoxyphenyl)-5-methyl-6-phenylisoxazolo[4,5...)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305859(5-methyl-3,6-diphenylisoxazolo[4,5-c]pyridin-4(5H)...)
Affinity DataIC50:  20nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305864(3-(2-methoxyphenyl)-5-methyl-6-phenylisoxazolo[4,5...)
Affinity DataIC50:  21nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50196289(6-(4-methoxyphenyl)-5-methyl-3-phenylisoxazolo[4,5...)
Affinity DataIC50:  22nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50196291(6-(benzo[d][1,3]dioxol-5-yl)-5-methyl-3-phenylisox...)
Affinity DataIC50:  26nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305877(6-(4-methoxyphenyl)-5-methyl-3-(pyridin-4-yl)isoxa...)
Affinity DataIC50:  26nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305862(3-(4-methoxyphenyl)-5-methyl-6-phenylisoxazolo[4,5...)
Affinity DataIC50:  29nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305873(6-(3-(dimethylamino)phenyl)-5-methyl-3-phenylisoxa...)
Affinity DataIC50:  31nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305868(5-methyl-3-phenyl-6-p-tolylisoxazolo[4,5-c]pyridin...)
Affinity DataIC50:  51nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305869(6-(4-fluorophenyl)-5-methyl-3-phenylisoxazolo[4,5-...)
Affinity DataIC50:  72nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305874(5-methyl-3-phenyl-6-(3-(trifluoromethyl)phenyl)iso...)
Affinity DataIC50:  96nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305865(5-methyl-6-phenyl-3-(pyridin-4-yl)isoxazolo[4,5-c]...)
Affinity DataIC50:  101nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305870(6-(4-(dimethylamino)phenyl)-5-methyl-3-phenylisoxa...)
Affinity DataIC50:  140nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305872(5-methyl-3-phenyl-6-(4-propylphenyl)isoxazolo[4,5-...)
Affinity DataIC50:  150nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305875(6-(3-fluoro-4-methoxyphenyl)-5-methyl-3-phenylisox...)
Affinity DataIC50:  210nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305866(5-methyl-6-phenyl-3-(pyridin-3-yl)isoxazolo[4,5-c]...)
Affinity DataIC50:  240nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50589650(CHEMBL5202961)
Affinity DataIC50:  263nMAssay Description:Negative allosteric modulation of rat mGlu7 in HEK cells expressing Galpha15 assessed as inhibition of L-AP4-induced response measured by calcium mob...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50589650(CHEMBL5202961)
Affinity DataIC50:  263nMAssay Description:Negative allosteric modulation of rat mGlu7 in HEK cells expressing Galpha15 assessed as inhibition of L-AP4-induced response measured by calcium mob...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50531687(CHEMBL4445682)
Affinity DataIC50:  347nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50531687(CHEMBL4445682)
Affinity DataIC50:  347nMAssay Description:Negative allosteric modulation of rat mGlu7 in HEK cells expressing Galpha15 assessed as inhibition of L-AP4-induced response measured by calcium mob...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50531687(CHEMBL4445682)
Affinity DataIC50:  350nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50553636(CHEMBL4750685)
Affinity DataIC50:  350nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50553631(CHEMBL4739931)
Affinity DataIC50:  370nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50553632(CHEMBL4745605)
Affinity DataIC50:  410nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50523865(CHEMBL4476495)
Affinity DataIC50:  501nMAssay Description:Negative allosteric modulation of rat mGlu7 in HEK cells expressing Galpha15 assessed as inhibition of L-AP4-induced response measured by calcium mob...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50280369(CHEMBL4169114)
Affinity DataIC50:  501nMAssay Description:Negative allosteric modulation of rat mGlu7 in HEK cells expressing Galpha15 assessed as inhibition of L-AP4-induced response measured by calcium mob...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50523865(CHEMBL4476495)
Affinity DataIC50:  501nMAssay Description:Negative allosteric modulation of rat mGlu7 in HEK cells expressing Galpha15 assessed as inhibition of L-AP4-induced response measured by calcium mob...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50553610(CHEMBL4793197)
Affinity DataIC50:  510nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50280369(CHEMBL4169114)
Affinity DataIC50:  510nMAssay Description:In vitro inhibitory activity against angiotensin I converting enzyme of rats.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50280369(CHEMBL4169114)
Affinity DataIC50:  513nMAssay Description:In vitro inhibitory activity against angiotensin I converting enzyme of rats.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50553635(CHEMBL4743016)
Affinity DataIC50:  540nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50280369(CHEMBL4169114)
Affinity DataIC50:  550nMAssay Description:Negative allosteric modulation of rat mGlu7 in HEK cells expressing Galpha15 assessed as inhibition of L-AP4-induced response measured by calcium mob...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50523865(CHEMBL4476495)
Affinity DataIC50:  570nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50305876(6-(3-bromo-4-methoxyphenyl)-5-methyl-3-phenylisoxa...)
Affinity DataIC50:  580nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50553630(CHEMBL4758459)
Affinity DataIC50:  600nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50553603(CHEMBL1349403)
Affinity DataIC50:  647nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50280374(CHEMBL4174742)
Affinity DataIC50:  650nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as decrease in glutamate-induced thallium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50553644(CHEMBL4785180)
Affinity DataIC50:  670nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50280374(CHEMBL4174742)
Affinity DataIC50:  676nMAssay Description:In vitro inhibitory activity against angiotensin I converting enzyme of rats.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50280374(CHEMBL4174742)
Affinity DataIC50:  676nMAssay Description:In vitro inhibitory activity against angiotensin I converting enzyme of rats.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50280370(CHEMBL4160395)
Affinity DataIC50:  708nMAssay Description:In vitro inhibitory activity against angiotensin I converting enzyme of rats.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50280370(CHEMBL4160395)
Affinity DataIC50:  710nMAssay Description:In vitro inhibitory activity against angiotensin I converting enzyme of rats.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50280368(CHEMBL4176971)
Affinity DataIC50:  759nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50280368(CHEMBL4176971)
Affinity DataIC50:  759nMAssay Description:Negative allosteric modulation of rat mGlu7 in HEK cells expressing Galpha15 assessed as inhibition of L-AP4-induced response measured by calcium mob...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50280368(CHEMBL4176971)
Affinity DataIC50:  759nMAssay Description:In vitro inhibitory activity against angiotensin I converting enzyme of rats.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50280368(CHEMBL4176971)
Affinity DataIC50:  760nMAssay Description:In vitro inhibitory activity against angiotensin I converting enzyme of rats.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50280368(CHEMBL4176971)
Affinity DataIC50:  760nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50280373(CHEMBL4161847)
Affinity DataIC50:  776nMAssay Description:In vitro inhibitory activity against angiotensin I converting enzyme of rats.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50280372(CHEMBL4165849)
Affinity DataIC50:  776nMAssay Description:In vitro inhibitory activity against angiotensin I converting enzyme of rats.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50280373(CHEMBL4161847)
Affinity DataIC50:  780nMAssay Description:In vitro inhibitory activity against angiotensin I converting enzyme of rats.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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