Compile Data Set for Download or QSAR
maximum 50k data
Found 23 of kd data for polymerid = 2236,50000534,5514
TargetTranslocator protein(Rattus norvegicus (rat))
Brain And Mind Research Institute

Curated by ChEMBL
LigandPNGBDBM22032(1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)isoq...)
Affinity DataKd:  0.600nMAssay Description:Displacement of [3H]PK11195 from TSPO in rat cortexMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Brain And Mind Research Institute

Curated by ChEMBL
LigandPNGBDBM22040(4 -chlorodiazepam | 4' Cl-diazepam | 7-chloro-...)
Affinity DataKd:  1.10nMAssay Description:Displacement of [3H]Ro5-4864 from TSPO in rat kainate lesioned striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Brain And Mind Research Institute

Curated by ChEMBL
LigandPNGBDBM22032(1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)isoq...)
Affinity DataKd:  2nMAssay Description:Binding affinity constant for peripheral (mitochondrial) Benzodiazepine receptorMore data for this Ligand-Target Pair
TargetTranslocator protein(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM22032(1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)isoq...)
Affinity DataKd:  2nMAssay Description:Binding affinity to human PBRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Brain And Mind Research Institute

Curated by ChEMBL
LigandPNGBDBM50255226((7-chloro-N,N,5-trimethyl-4-oxo-3-phenyl-3,5-dihyd...)
Affinity DataKd:  3nMAssay Description:Displacement of [3H]SSR180575 from TSPO in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Brain And Mind Research Institute

Curated by ChEMBL
LigandPNGBDBM50316600(CHEMBL1097176 | N,N-Dipropyl-[5-isothiocyanato-2-p...)
Affinity DataKd:  3.17nMAssay Description:Irreversible binding affinity to TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Brain And Mind Research Institute

Curated by ChEMBL
LigandPNGBDBM22040(4 -chlorodiazepam | 4' Cl-diazepam | 7-chloro-...)
Affinity DataKd:  3.5nMAssay Description:Binding affinity constant for Benzodiazepine receptor in rat RG-2 glioma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50255226((7-chloro-N,N,5-trimethyl-4-oxo-3-phenyl-3,5-dihyd...)
Affinity DataKd:  3.5nMAssay Description:Binding affinity to human PBRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50045877(2-(2-(4-fluorophenyl)-1H-indol-3-yl)-N,N-dihexylac...)
Affinity DataKd:  4nMAssay Description:Binding affinity to human PBRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Brain And Mind Research Institute

Curated by ChEMBL
LigandPNGBDBM50316601(CHEMBL1097503 | N,N-Dihexyl-[5-isothiocyanato-2-ph...)
Affinity DataKd:  5.07nMAssay Description:Irreversible binding affinity to TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM22040(4 -chlorodiazepam | 4' Cl-diazepam | 7-chloro-...)
Affinity DataKd:  6nMAssay Description:Binding affinity to human PBRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Brain And Mind Research Institute

Curated by ChEMBL
LigandPNGBDBM50316602(CHEMBL1099012 | N-(5-Isothiocyanato-2-phenylindol-...)
Affinity DataKd:  8.31nMAssay Description:Irreversible binding affinity to TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Brain And Mind Research Institute

Curated by ChEMBL
LigandPNGBDBM50021058(7-Chloro-1-methyl-5-phenyl-2,3-dihydro-1H-benzo[e]...)
Affinity DataKd: >10nMAssay Description:Binding affinity constant for peripheral (mitochondrial) Benzodiazepine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM22032(1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)isoq...)
Affinity DataKd:  11nMAssay Description:Inhibition concentration against human adenosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM22032(1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)isoq...)
Affinity DataKd:  11nMAssay Description:Binding affinity to recombinant human TSPO by SPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50336914(3-[(21S,22S)-16-ethenyl-11-ethyl-12,17,21,26-tetra...)
Affinity DataKd:  40nMAssay Description:Binding affinity to PBRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50279019(CHEMBL1315992)
Affinity DataKd:  40nMAssay Description:Binding affinity to C-terminal DDK-tagged human recombinant full-length TSPO expressed in HEK293 cells by SPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Brain And Mind Research Institute

Curated by ChEMBL
LigandPNGBDBM22040(4 -chlorodiazepam | 4' Cl-diazepam | 7-chloro-...)
Affinity DataKd:  58nMAssay Description:Binding affinity constant for peripheral (mitochondrial) Benzodiazepine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50279015(CHEMBL4174207)
Affinity DataKd:  61nMAssay Description:Binding affinity to C-terminal DDK-tagged human recombinant full-length TSPO expressed in HEK293 cells by SPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210940(CHEMBL3948914)
Affinity DataKd:  108nMAssay Description:Binding affinity to recombinant human TSPO by SPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Brain And Mind Research Institute

Curated by ChEMBL
LigandPNGBDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKd:  213nMAssay Description:Binding affinity constant for peripheral (mitochondrial) Benzodiazepine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Brain And Mind Research Institute

Curated by ChEMBL
LigandPNGBDBM22040(4 -chlorodiazepam | 4' Cl-diazepam | 7-chloro-...)
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity constant for Benzodiazepine receptor in normal rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Brain And Mind Research Institute

Curated by ChEMBL
LigandPNGBDBM22040(4 -chlorodiazepam | 4' Cl-diazepam | 7-chloro-...)
Affinity DataKd:  4.00E+3nMAssay Description:Binding affinity constant for Benzodiazepine receptor in rat C6 glioma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed