Affinity DataKd: 0.160nMAssay Description:Binding affinity to human N-His6-tagged B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKd: 0.180nMAssay Description:Binding constant for BRAF(V600E) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 0.190nMAssay Description:Binding constant for BRAF kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 0.300nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
Affinity DataKd: 0.300nMAssay Description:Binding affinity at bRaf kinase in fluorescent ligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.330nMAssay Description:Binding affinity to DNA-tagged BRAF (unknown origin) V600E mutant by KINOMEscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.370nMAssay Description:Binding affinity to DNA-tagged BRAF (unknown origin) by KINOMEscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.5nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
Affinity DataKd: 0.5nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
Affinity DataKd: 0.5nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
Affinity DataKd: 0.700nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
Affinity DataKd: 0.900nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
Affinity DataKd: 1.30nMAssay Description:Binding affinity to wild-type human partial length BRAF (S429 to E741 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
Affinity DataKd: 1.30nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
Affinity DataKd: 1.30nMAssay Description:Binding affinity at bRaf kinase in fluorescent ligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.40nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
Affinity DataKd: 1.70nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
Affinity DataKd: 2nMAssay Description:Binding affinity at bRaf kinase in fluorescent ligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKd: 2nMAssay Description:Binding affinity to DNA-tagged BRAF (unknown origin) V600E mutant by KINOMEscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.40nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
Affinity DataKd: 2.40nMAssay Description:Binding affinity to DNA-tagged BRAF (unknown origin) by KINOMEscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.40nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
Affinity DataKd: 2.40nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
Affinity DataKd: 2.40nMAssay Description:Binding affinity at bRaf kinase in fluorescent ligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.60nMAssay Description:Binding affinity to DNA-tagged BRAF (unknown origin) by KINOMEscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.70nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
Affinity DataKd: 2.70nMAssay Description:Binding affinity to DNA-tagged BRAF (unknown origin) V600E mutant by KINOMEscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 4.20nMAssay Description:Binding affinity at bRaf kinase in fluorescent ligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKd: 4.40nMAssay Description:Binding constant for BRAF(V600E) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 4.80nMAssay Description:Binding affinity at bRaf kinase in fluorescent ligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKd: 4.90nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
Affinity DataKd: 5nMAssay Description:Binding affinity at bRaf kinase in fluorescent ligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKd: 5.10nMAssay Description:Binding affinity to DNA-tagged BRAF (unknown origin) by KINOMEscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 5.30nMAssay Description:Binding affinity at bRaf kinase in fluorescent ligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKd: 5.70nMAssay Description:Binding affinity at bRaf kinase in fluorescent ligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKd: 5.70nMAssay Description:Binding constant for BRAF kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 6nMAssay Description:Binding affinity at bRaf kinase in fluorescent ligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKd: 6.30nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
Affinity DataKd: 7.20nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
Affinity DataKd: 7.30nMAssay Description:Binding affinity to DNA-tagged BRAF (unknown origin) V600E mutant by KINOMEscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 8nMAssay Description:Binding affinity at bRaf kinase in fluorescent ligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKd: 9.5nMAssay Description:Binding affinity to DNA-tagged BRAF (unknown origin) by KINOMEscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Binding affinity at bRaf kinase in fluorescent ligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKd: 11nMAssay Description:Binding affinity at bRaf kinase in fluorescent ligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKd: 14nMAssay Description:Binding affinity at bRaf kinase in fluorescent ligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKd: 14nMAssay Description:Binding affinity to BRAF V600E (unknown origin) assessed as dissociation constant measured by ambit kinomescan assayMore data for this Ligand-Target Pair
Affinity DataKd: 14nMAssay Description:Binding affinity to DNA-tagged BRAF (unknown origin) V600E mutant by KINOMEscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 15.8nMpH: 7.5 T: 2°CAssay Description:The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...More data for this Ligand-Target Pair
Affinity DataKd: 17nMAssay Description:Binding affinity at bRaf kinase in fluorescent ligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKd: 21nMAssay Description:Binding affinity at bRaf kinase in fluorescent ligand displacement assayMore data for this Ligand-Target Pair