Compile Data Set for Download or QSAR
maximum 50k data
Found 124 of kd data for polymerid = 4514
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM36409(2-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin...)
Affinity DataKd:  7.60nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM6568(6-(2,6-dichlorophenyl)-8-methyl-2-{[3-(methylsulfa...)
Affinity DataKd:  9.10nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50314071(2-(2,4-difluorophenyl)-6-(1-(2,6-difluorophenyl)ur...)
Affinity DataKd:  92nMAssay Description:Binding affinity to ACVR2betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50355496(CHEMBL1908397)
Affinity DataKd:  370nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataKd:  570nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataKd:  570nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataKd:  570nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM31085(1-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluorom...)
Affinity DataKd:  1.40E+3nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM26474(5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino...)
Affinity DataKd:  2.40E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM31099(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S)-3-hydroxy...)
Affinity DataKd:  2.40E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM26474(5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino...)
Affinity DataKd:  2.40E+3nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataKd:  2.40E+3nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataKd:  2.40E+3nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM26474(5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino...)
Affinity DataKd:  2.40E+3nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM25617(N-[3-({5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl}carb...)
Affinity DataKd:  3.20E+3nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)
Affinity DataKd:  3.80E+3nMAssay Description:Binding affinity to ACVR2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)
Affinity DataKd:  3.80E+3nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM482158(BDBM50242742 | TAE684)
Affinity DataKd:  4.30E+3nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM31096(CHEMBL290084 | Staurosporine | cid_451705)
Affinity DataKd:  4.60E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataKd:  4.60E+3nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataKd:  4.60E+3nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM13531(4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridy...)
Affinity DataKd:  4.80E+3nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM13531(4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridy...)
Affinity DataKd:  4.80E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM25117(AG-013736 | AXITINIB | N-methyl-2-({3-[(E)-2-(pyri...)
Affinity DataKd:  5.20E+3nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)
Affinity DataKd:  5.90E+3nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)
Affinity DataKd:  5.90E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50326053(CHEMBL608533 | PKC-412)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to ACVR2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50326053(CHEMBL608533 | PKC-412)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50326053(CHEMBL608533 | PKC-412)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to ACVR2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM13535(4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to ACVR2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50326054(CHEMBL1240703)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to ACVR2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to ACVR2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to ACVR2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM31088(1-methyl-5-[2-[5-(trifluoromethyl)-1H-imidazol-2-y...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM15138(5-indazolyl pyridine 11g | 5-{5-[(2S)-2-amino-3-ph...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM12621(2,4-Diamino-5-ketopyrimidine 39 | 5-[(2,3-difluoro...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM24773(AMG 706 | AMG-706 | Motesanib | N-(3,3-dimethyl-1,...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50355497(AZD-6244 | CHEMBL1614701)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM25919(BMS-345541 | BMS345541 | CHEMBL471496 | N-(2-amino...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50355494(CHEMBL1908396)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM32362(5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50331096(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxy-7...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50322823((S)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahy...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM25118((3Z)-4-amino-5-fluoro-3-[5-(4-methylpiperazino)-1,...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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