Affinity DataKd: 0.240nMAssay Description:Binding affinity to human ALK by Ambit titration assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.360nMAssay Description:Binding affinity to human ALK by Ambit titration assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.550nMAssay Description:Binding constant for ALK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.10nMAssay Description:Binding constant for ALK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.30nMAssay Description:Binding affinity to wild-type human partial length ALK (I1088 to E1409 residues) expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.30nMAssay Description:Binding affinity to human ALK (1088 to 1409 residues) expressed in mammalian system by KINOMEscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.30nMAssay Description:Binding constant for ALK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 4.40nMAssay Description:Binding affinity to ALK (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 5.70nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Affinity DataKd: 5.70nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Affinity DataKd: 6.80nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Affinity DataKd: 6.80nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Affinity DataKd: 8.20nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Affinity DataKd: 8.20nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Affinity DataKd: 14nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Affinity DataKd: 14nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Affinity DataKd: 19nMAssay Description:Binding affinity to wild-type human partial length ALK (I1088 to E1409 residues) expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 23nMAssay Description:Binding affinity to human ALK F1174L mutant (1088 to 1409 residues) expressed in mammalian expression system by kinome scan-based assayMore data for this Ligand-Target Pair
Affinity DataKd: 28nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Affinity DataKd: 28nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Affinity DataKd: 31nMAssay Description:Binding constant for ALK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 32nMAssay Description:Binding constant for ALK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 32nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 32nMAssay Description:Binding constant for ALK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 37nMAssay Description:Binding affinity to wild-type human partial length ALK (I1088 to E1409 residues) expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 54nMAssay Description:Binding affinity to wild-type human partial length ALK (I1088 to E1409 residues) expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 69nMAssay Description:Binding constant for ALK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 71nMAssay Description:Binding constant for ALK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 78nMAssay Description:Binding affinity to wild-type human partial length ALK (I1088 to E1409 residues) expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 80nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Affinity DataKd: 80nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Affinity DataKd: 89nMAssay Description:Binding affinity to wild type human ALK (1088 to 1409 residues) expressed in mammalian expression system by kinome scan-based assayMore data for this Ligand-Target Pair
Affinity DataKd: 150nMAssay Description:Binding affinity to wild-type human partial length ALK (I1088 to E1409 residues) expressed in mammalian expression system by Kinomescan method relati...More data for this Ligand-Target Pair
Affinity DataKd: 160nMAssay Description:Binding constant for ALK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 170nMAssay Description:Binding constant for ALK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 170nMAssay Description:Binding constant for ALK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 170nMAssay Description:Binding affinity to ALKMore data for this Ligand-Target Pair
Affinity DataKd: 170nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 172nMAssay Description:Binding affinity to recombinant human full length N-terminal GST-tagged ALK (1058 to 1620 residues) expressed in baculovirus expression system using ...More data for this Ligand-Target Pair
Affinity DataKd: 180nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Affinity DataKd: 180nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Affinity DataKd: 200nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Affinity DataKd: 200nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Affinity DataKd: 230nMAssay Description:Binding affinity to recombinant human full length N-terminal GST-tagged ALK (1058 to 1620 residues) expressed in baculovirus expression system using ...More data for this Ligand-Target Pair
Affinity DataKd: 240nMAssay Description:Binding constant for ALK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 270nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 270nMAssay Description:Binding constant for ALK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 270nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Affinity DataKd: 270nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair