Affinity DataKd: 0.180nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Affinity DataKd: 0.180nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Affinity DataKd: 1.70nMAssay Description:Binding affinity to recombinant human biotinylated and N-terminal DYKDDDDK-tagged TrkB kinase domain (456-822 residues) expressed in sf21 cells asses...More data for this Ligand-Target Pair
Affinity DataKd: 3.10nMAssay Description:Binding affinity to wild-type human partial length TRKB (Q547 to G838 residues) expressed in mammalian expression system by Kinomescan method relativ...More data for this Ligand-Target Pair
Affinity DataKd: 3.80nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 3.80nMAssay Description:Binding constant for TRKB kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 3.80nMAssay Description:Binding constant for TRKB kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 4.10nMAssay Description:Binding constant for TRKB kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Binding affinity to recombinant human TrkB receptor ECD assessed as dissociation constantMore data for this Ligand-Target Pair
Affinity DataKd: 11nMAssay Description:Binding affinity to human TrkBMore data for this Ligand-Target Pair
Affinity DataKd: 14nMAssay Description:Binding affinity to TRKBMore data for this Ligand-Target Pair
Affinity DataKd: 14nMAssay Description:Binding constant for TRKB kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 19nMAssay Description:Binding constant for TRKB kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 22nMAssay Description:Binding affinity to wild type human partial length TRKB (547 to 838 residues) expressed in mammalian expression system preincubated for 1 hr measured...More data for this Ligand-Target Pair
Affinity DataKd: 22nMAssay Description:Binding affinity to TrkB (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 22nMAssay Description:Binding affinity to wild type human partial length TRKB (547 to 838 residues) expressed in mammalian expression system preincubated for 1 hr measured...More data for this Ligand-Target Pair
Affinity DataKd: 23nMAssay Description:Binding affinity to human partial length TRKB expressed in mammalian expression system by kinomescan methodMore data for this Ligand-Target Pair
Affinity DataKd: 28nMAssay Description:Binding affinity to human partial length TRKB expressed in mammalian expression system by kinomescan methodMore data for this Ligand-Target Pair
Affinity DataKd: 36nMAssay Description:Binding constant for TRKB kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 36nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 36nMAssay Description:Binding constant for TRKB kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 37nMAssay Description:Binding constant for TRKB kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 54nMAssay Description:Binding affinity to human TRKBMore data for this Ligand-Target Pair
Affinity DataKd: 54nMAssay Description:Binding affinity to human TRKBMore data for this Ligand-Target Pair
Affinity DataKd: 60nMAssay Description:Binding affinity to human partial length TRKB expressed in mammalian expression system by kinomescan methodMore data for this Ligand-Target Pair
Affinity DataKd: 112nMAssay Description:Binding affinity to human partial length TRKB expressed in mammalian expression system by kinomescan methodMore data for this Ligand-Target Pair
Affinity DataKd: 120nMAssay Description:Binding constant for TRKB kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 130nMAssay Description:Binding constant for TRKB kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 140nMAssay Description:Binding constant for TRKB kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 187nMAssay Description:Binding affinity to human partial length TRKB expressed in mammalian expression system by kinomescan methodMore data for this Ligand-Target Pair
Affinity DataKd: 190nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 190nMAssay Description:Binding constant for TRKB kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 190nMAssay Description:Binding constant for TRKB kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 240nMAssay Description:Binding constant for TRKB kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 240nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 240nMAssay Description:Binding constant for TRKB kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 310nMAssay Description:Binding constant for TRKB kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 310nMAssay Description:Binding constant for TRKB kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 310nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 310nMAssay Description:Binding affinity to TRKBMore data for this Ligand-Target Pair
Affinity DataKd: 320nMAssay Description:Binding affinity to TrkB receptor extracellular domain (unknown origin) after 10 mins by liquid Scatchard plot analysisMore data for this Ligand-Target Pair
Affinity DataKd: 360nMAssay Description:Binding constant for TRKB kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 490nMAssay Description:Binding constant for TRKB kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 570nMAssay Description:Binding constant for TRKB kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 570nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 570nMAssay Description:Binding constant for TRKB kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 590nMAssay Description:Binding constant for TRKB kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 590nMAssay Description:Binding affinity to TRKBMore data for this Ligand-Target Pair
Affinity DataKd: 590nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 590nMAssay Description:Binding constant for TRKB kinase domainMore data for this Ligand-Target Pair