Compile Data Set for Download or QSAR
maximum 50k data
Found 11 of kd data for polymerid = 6845
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Huazhong Agricultural University

Curated by ChEMBL
LigandPNGBDBM50522839(CHEMBL2095003 | DNDI1417825)
Affinity DataKd:  720nMAssay Description:Binding affinity to N-terminal 6-His-tagged IDH1 R132C mutant (unknown origin) expressed in BL21 cells assessed as equilibrium dissociation constant ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Huazhong Agricultural University

Curated by ChEMBL
LigandPNGBDBM50068270((E)-3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-y...)
Affinity DataKd:  2.81E+3nMAssay Description:Binding affinity to IDH1 R132C mutant (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Huazhong Agricultural University

Curated by ChEMBL
LigandPNGBDBM50522839(CHEMBL2095003 | DNDI1417825)
Affinity DataKd:  3.80E+3nMAssay Description:Binding affinity to N-terminal 6-His-tagged IDH1 R132H mutant (unknown origin) expressed in BL21 cells assessed as equilibrium dissociation constant ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Huazhong Agricultural University

Curated by ChEMBL
LigandPNGBDBM50111796(CHEMBL3605384)
Affinity DataKd:  5.90E+3nMAssay Description:Binding affinity to recombinant human IDH1 R132H mutant expressed in Escherichia coli by isothermal titration calorimetric analysis in absence of NAD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Huazhong Agricultural University

Curated by ChEMBL
LigandPNGBDBM50111796(CHEMBL3605384)
Affinity DataKd:  8.90E+3nMAssay Description:Binding affinity to recombinant human IDH1 R132H mutant expressed in Escherichia coli by isothermal titration calorimetric analysis in presence of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Huazhong Agricultural University

Curated by ChEMBL
LigandPNGBDBM50068270((E)-3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-y...)
Affinity DataKd:  1.28E+4nMAssay Description:Binding affinity to IDH1 R132H mutant (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Huazhong Agricultural University

Curated by ChEMBL
LigandPNGBDBM50557557(CHEMBL504910)
Affinity DataKd:  1.53E+4nMAssay Description:Binding affinity to C-terminal His6-tagged IDH1 R132H mutant (unknown origin) expressed in Escherichia coli BL21 (DE) measured after 20 mins by Red-N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Huazhong Agricultural University

Curated by ChEMBL
LigandPNGBDBM50378034(CHEMBL504404 | NSC-287088 | PHYSALIN B)
Affinity DataKd:  4.53E+4nMAssay Description:Binding affinity to C-terminal His6-tagged IDH1 R132H mutant (unknown origin) expressed in Escherichia coli BL21 (DE) measured after 20 mins by Red-N...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Huazhong Agricultural University

Curated by ChEMBL
LigandPNGBDBM50111796(CHEMBL3605384)
Affinity DataKd:  4.60E+4nMAssay Description:Binding affinity to recombinant human IDH1 R132H mutant expressed in Escherichia coli by isothermal titration calorimetric analysis in presence of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Huazhong Agricultural University

Curated by ChEMBL
LigandPNGBDBM50522839(CHEMBL2095003 | DNDI1417825)
Affinity DataKd: >5.00E+4nMAssay Description:Binding affinity to N-terminal 6-His-tagged wild type IDH1 (unknown origin) expressed in BL21 cells assessed as equilibrium dissociation constant by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Huazhong Agricultural University

Curated by ChEMBL
LigandPNGBDBM50068270((E)-3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-y...)
Affinity DataKd: >5.00E+4nMAssay Description:Binding affinity to IDH1 (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed