Compile Data Set for Download or QSAR
maximum 50k data
Found 174 of kd data for polymerid = 694
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM81377(FIIN-1)
Affinity DataIC50:  9.20nM Kd:  2.80nMAssay Description:In vitro kinase assay profiled against a panel of different kinase binding assay using Ambit kinomeScan technology. Biochemical IC50 values were det...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM81378(FRIN-1)
Affinity DataKd:  3.10nMAssay Description:In vitro kinase assay profiled against a panel of different kinase binding assay using Ambit kinomeScan technology. Biochemical IC50 values were det...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM50420961(CHEMBL2088096)
Affinity DataKd:  3.10nMAssay Description:Binding affinity to N-terminal 6xHis-tagged human recombinant FGFR1 (458 to 765) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM50420961(CHEMBL2088096)
Affinity DataKd:  5.80nMAssay Description:Binding affinity to N-terminal 6xHis-tagged human recombinant FGFR1 (458 to 765) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM373519(US10421747, Compound 2 | US9902714, Compound 2)
Affinity DataKd:  17nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan® technologyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM373519(US10421747, Compound 2 | US9902714, Compound 2)
Affinity DataKd:  17nMAssay Description:FGFR1: In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM60665(BDBM50249542 | US9145414, R406 | US9212178, R406)
Affinity DataKd:  44nMAssay Description:Binding constant for FGFR1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM482158(BDBM50242742 | TAE684)
Affinity DataKd:  47nMAssay Description:Binding constant for FGFR1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM50331096(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxy-7...)
Affinity DataKd:  53nMAssay Description:Binding constant for FGFR1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM373526(US10421747, Compound 9 | US9902714, Compound 9)
Affinity DataKd:  54nMAssay Description:FGFR1: In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM373526(US10421747, Compound 9 | US9902714, Compound 9)
Affinity DataKd:  54nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan® technologyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataKd:  60nMAssay Description:Average Binding Constant for FGFR1; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM6568(6-(2,6-dichlorophenyl)-8-methyl-2-{[3-(methylsulfa...)
Affinity DataKd:  62nMAssay Description:Binding constant for FGFR1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM50420964(CHEMBL2088100)
Affinity DataKd:  68nMAssay Description:Binding affinity to N-terminal 6xHis-tagged human recombinant FGFR1 (458 to 765) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM50420964(CHEMBL2088100)
Affinity DataKd:  69nMAssay Description:Binding affinity to N-terminal 6xHis-tagged human recombinant FGFR1 (458 to 765) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM50565310(CHEMBL4792981)
Affinity DataKd:  76nMAssay Description:Binding affinity to wild-type human partial length FGFR1 (P357 to V669 residues) expressed in bacterial expression system by Kinomescan method relati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM373525(US10421747, Compound 7 | US9902714, Compound 7)
Affinity DataKd:  79nMAssay Description:FGFR1: In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM373525(US10421747, Compound 7 | US9902714, Compound 7)
Affinity DataKd:  79nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan® technologyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataKd:  90nMAssay Description:Binding constant for FGFR1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM31096(CHEMBL290084 | Staurosporine | cid_451705)
Affinity DataKd:  90nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataKd:  90nMAssay Description:Binding constant for FGFR1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)
Affinity DataKd:  92nMAssay Description:Binding constant for FGFR1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataKd:  99nMAssay Description:Binding constant for FGFR1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM588120(US11542247, Compound 9)
Affinity DataKd:  141nMAssay Description:FGFR1: In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) is incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM25118((3Z)-4-amino-5-fluoro-3-[5-(4-methylpiperazino)-1,...)
Affinity DataKd:  150nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM25118((3Z)-4-amino-5-fluoro-3-[5-(4-methylpiperazino)-1,...)
Affinity DataKd:  150nMAssay Description:Binding constant for FGFR1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM25118((3Z)-4-amino-5-fluoro-3-[5-(4-methylpiperazino)-1,...)
Affinity DataKd:  150nMAssay Description:Binding constant for FGFR1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM50505541(CHEMBL4465866)
Affinity DataKd:  268nMAssay Description:Binding affinity to recombinant N-terminal His-FLAG-GST-tagged FGFR1 (unknown origin) (396 to 820 residues) expressed in baculovirus infected Sf9 ins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM50332294(CHEMBL1287853 | N-tert-butyl-3-(5-methyl-2-(4-(2-(...)
Affinity DataKd:  280nMAssay Description:Binding constant for FGFR1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)
Affinity DataKd:  310nMAssay Description:Binding constant for FGFR1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)
Affinity DataKd:  310nMAssay Description:Binding affinity to FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM50495331(CHEMBL3109570)
Affinity DataKd:  311nMAssay Description:Binding affinity to N-terminal 6xHis-tagged human recombinant FGFR1 (458 to 765) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM373274(US10421747, Compound 1 | US9902714, Compound 1)
Affinity DataKd:  314nMAssay Description:FGFR1: In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM373274(US10421747, Compound 1 | US9902714, Compound 1)
Affinity DataKd:  314nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan® technologyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM588101(US11542247, Compound 3)
Affinity DataKd:  331nMAssay Description:FGFR1: In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) is incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM50355496(CHEMBL1908397)
Affinity DataKd:  370nMAssay Description:Binding constant for FGFR1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM25117(AG-013736 | AXITINIB | N-methyl-2-({3-[(E)-2-(pyri...)
Affinity DataKd:  380nMAssay Description:Binding constant for FGFR1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM50605511(CHEMBL5193786)
Affinity DataKd:  380nMAssay Description:Binding affinity to wild-type human partial length FGFR1 (P357 to V669 residues) expressed in bacterial expression system by Kinomescan assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM50495331(CHEMBL3109570)
Affinity DataKd:  447nMAssay Description:Binding affinity to N-terminal 6xHis-tagged human recombinant FGFR1 (458 to 765) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Affinity DataKd:  520nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Affinity DataKd:  520nMAssay Description:Binding constant for FGFR1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Affinity DataKd:  520nMAssay Description:Binding affinity to FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Affinity DataKd:  520nMAssay Description:Binding constant for FGFR1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)
Affinity DataKd:  550nMAssay Description:Binding constant for FGFR1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)
Affinity DataKd:  550nMAssay Description:Binding constant for FGFR1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)
Affinity DataKd:  550nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM21(CHEMBL24828 | N-(4-bromo-2-fluorophenyl)-6-methoxy...)
Affinity DataKd:  560nMAssay Description:Binding constant for FGFR1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM21(CHEMBL24828 | N-(4-bromo-2-fluorophenyl)-6-methoxy...)
Affinity DataKd:  560nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM21(CHEMBL24828 | N-(4-bromo-2-fluorophenyl)-6-methoxy...)
Affinity DataKd:  560nMAssay Description:Binding constant for FGFR1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM36409(2-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin...)
Affinity DataKd:  570nMAssay Description:Binding constant for FGFR1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 174 total ) | Next | Last >>
Jump to: