Compile Data Set for Download or QSAR
maximum 50k data
Found 498 of ki data for polymerid = 1805,50000240,50003784,50004350
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17428(1,2,4-Triazole Compound, 86 | N-[5-(benzylsulfanyl...)
Affinity DataKi:  0.0400nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17355(1,2,4-Triazole Compound, 13 | 5-(benzylsulfanyl)-N...)
Affinity DataKi:  0.0400nM ΔG°:  -58.8kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17388(1,2,4-Triazole Compound, 46 | 5-(benzylsulfanyl)-N...)
Affinity DataKi:  0.0500nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50353018(CHEMBL1821980 | CHEMBL1852660)
Affinity DataKi:  0.0600nMAssay Description:Inhibition of human APNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17365(1,2,4-Triazole Compound, 23 | 5-(benzylsulfanyl)-N...)
Affinity DataKi:  0.0700nM ΔG°:  -57.4kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17390(1,2,4-Triazole Compound, 48 | 5-{[(2-fluorophenyl)...)
Affinity DataKi:  0.130nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17362(1,2,4-Triazole Compound, 20 | 5-[(3-methylbut-2-en...)
Affinity DataKi:  0.150nM ΔG°:  -55.5kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078125((1-Amino-3-phenyl-propyl)-phosphinic acid | CHEMBL...)
Affinity DataKi:  0.160nMAssay Description:Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM50524862(CHEMBL4475680)
Affinity DataKi:  0.160nMAssay Description:Inhibition of 5-[(S)-3-(3-Chloro-5-fluoro-benzylcarbamoyl)-3-hydroxy-2-oxopyrrolidin-1-yl]-1H-indole-2-carboxylic Acid (3-Amino-propyl)-amide-Dy647 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM50524862(CHEMBL4475680)
Affinity DataKi:  0.160nMAssay Description:Inhibition of 5-[(S)-3-(3-Chloro-5-fluoro-benzylcarbamoyl)-3-hydroxy-2-oxopyrrolidin-1-yl]-1H-indole-2-carboxylic Acid (3-Amino-propyl)-amide-Dy647 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17395(1,2,4-Triazole Compound, 53 | N-(4-methoxyphenyl)-...)
Affinity DataKi:  0.160nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50025070(CHEMBL3355110)
Affinity DataKi:  0.210nMAssay Description:Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17358(1,2,4-Triazole Compound, 16 | 5-{[(2-fluorophenyl)...)
Affinity DataKi:  0.230nM ΔG°:  -54.5kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50025048(CHEMBL3355099)
Affinity DataKi:  0.230nMAssay Description:Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17430(1,2,4-Triazole Compound, 88 | N-(5-{[(2-fluorophen...)
Affinity DataKi:  0.300nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50353018(CHEMBL1821980 | CHEMBL1852660)
Affinity DataKi:  0.350nMAssay Description:Inhibition of human APN using L-leucine-p-nitroanilide as substrate measured every 10 mins for 2 hrs by spectriphotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17411(1,2,4-Triazole Compound, 69 | methyl 4-[(5-{[(2-fl...)
Affinity DataKi:  0.410nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17377(1,2,4-Triazole Compound, 35 | 5-(benzylsulfanyl)-N...)
Affinity DataKi:  0.430nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17416(1,2,4-Triazole Compound, 74 | methyl 4-({5-[(3-met...)
Affinity DataKi:  0.5nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17352(1,2,4-Triazole Compound, 6 | 5-(benzylsulfanyl)-N-...)
Affinity DataKi:  0.5nM ΔG°:  -52.6kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17431(1,2,4-Triazole Compound, 89 | N-(5-{[(3,4-difluoro...)
Affinity DataKi:  0.5nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17385(1,2,4-Triazole Compound, 43 | N-(4-chlorophenyl)-5...)
Affinity DataKi:  0.520nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17380(1,2,4-Triazole Compound, 38 | N-(4-chlorophenyl)-5...)
Affinity DataKi:  0.610nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17368(1,2,4-Triazole Compound, 26 | 5-{[(2-fluorophenyl)...)
Affinity DataKi:  0.650nM ΔG°:  -51.9kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50025066(CHEMBL3355109)
Affinity DataKi:  0.690nMAssay Description:Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17408(1,2,4-Triazole Compound, 66 | methyl 4-{[5-(benzyl...)
Affinity DataKi:  0.700nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17354(1,2,4-Triazole Compound, 12 | N-phenyl-5-[(thiophe...)
Affinity DataKi:  0.75nM ΔG°:  -51.6kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50316049(1-amino-3-phenylpropylphosphonic acid | CHEMBL1090...)
Affinity DataKi:  0.790nMAssay Description:Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17418(1,2,4-Triazole Compound, 76 | methyl 4-[(5-{[(5-me...)
Affinity DataKi:  0.800nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM401307(US10005756, Compound A78)
Affinity DataKi:  0.900nMAssay Description:Inhibition of 5-[(S)-3-(3-Chloro-5-fluoro-benzylcarbamoyl)-3-hydroxy-2-oxopyrrolidin-1-yl]-1H-indole-2-carboxylic Acid (3-Amino-propyl)-amide-Dy647 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM401307(US10005756, Compound A78)
Affinity DataKi:  0.900nMAssay Description:Inhibition of 5-[(S)-3-(3-Chloro-5-fluoro-benzylcarbamoyl)-3-hydroxy-2-oxopyrrolidin-1-yl]-1H-indole-2-carboxylic Acid (3-Amino-propyl)-amide-Dy647 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17414(1,2,4-Triazole Compound, 72 | methyl 4-({5-[(pyrid...)
Affinity DataKi:  0.900nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17405(1,2,4-Triazole Compound, 63 | N-(3,4-dimethoxyphen...)
Affinity DataKi:  0.900nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17413(1,2,4-Triazole Compound, 71 | methyl 4-({5-[(pyrid...)
Affinity DataKi:  0.900nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17468(1,2,3-triazole analogue, 24 | 5-(3,4-dibromophenyl...)
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17461(1,2,3-triazole analogue, 17 | 5-(4-iodophenyl)-1H-...)
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17446((3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-m...)
Affinity DataKi:  1nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17442(1,2,4-Triazole Compound, 101 | 5-[(3-methylbut-2-e...)
Affinity DataKi:  1nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50025099(CHEMBL3355111)
Affinity DataKi:  1.10nMAssay Description:Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17373(1,2,4-Triazole Compound, 31 | 5-[(3-methylbut-2-en...)
Affinity DataKi:  1.20nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50025041(CHEMBL3355106)
Affinity DataKi:  1.30nMAssay Description:Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17412(1,2,4-Triazole Compound, 70 | methyl 4-[(5-{[(3,4-...)
Affinity DataKi:  1.30nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17400(1,2,4-Triazole Compound, 58 | N-(3,4-dimethoxyphen...)
Affinity DataKi:  1.30nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17381(1,2,4-Triazole Compound, 39 | N-(4-chlorophenyl)-5...)
Affinity DataKi:  1.5nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17436(1,2,4-Triazole Compound, 94 | N-(5-{[(5-methyl-1,2...)
Affinity DataKi:  1.5nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17396(1,2,4-Triazole Compound, 54 | N-(4-methoxyphenyl)-...)
Affinity DataKi:  1.60nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50025043(CHEMBL3355104)
Affinity DataKi:  1.70nMAssay Description:Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17429(1,2,4-Triazole Compound, 87 | N-(5-{[(2-methylphen...)
Affinity DataKi:  1.70nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17397(1,2,4-Triazole Compound, 55 | 5-(benzylsulfanyl)-N...)
Affinity DataKi:  1.70nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17387(1,2,4-Triazole Compound, 45 | N-(4-chlorophenyl)-5...)
Affinity DataKi:  1.80nMAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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