Compile Data Set for Download or QSAR
maximum 50k data
Found 4322 of ki data for polymerid = 3430,49000058,49000060,49000064,49000065,49000066,7150,7885
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50068612(2-(8-Bromo-benzo[1,2-b;4,5-b']difuran-4-yl)-1-meth...)
Affinity DataKi:  0.0200nMAssay Description:Binding activity against cloned human 5-hydroxytryptamine 2C receptor using [125I]-DOI as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50098525(2-(8-Bromo-benzo[1,2-b;4,5-b']difuran-4-yl)-1-meth...)
Affinity DataKi:  0.110nMAssay Description:Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50145624(CHEMBL3764539)
Affinity DataKi:  0.156nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptor in Sprague-Dawley rat brain cortex incubated for 15 mins by liquid scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM472930((R)-4-propyl-6,6a,7,8,9,10-hexahydro-5H- pyrazino[...)
Affinity DataKi:  0.158nMAssay Description:Displacement of [125I]-DOI from recombinant human 5HT2CR transfected in human HEK293 cells incubated for 45 mins by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50115642((+)-65-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2,...)
Affinity DataKi:  0.160nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2C receptor was determined using [3H]-mesulergineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM85097(CAS_181632-25-7 | CHEMBL14563 | SB 242084)
Affinity DataKi:  0.160nMAssay Description:Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat whole brain membranes after 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(PIG)
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM84994(CAS_163091 | NSC_163091 | ORG-5222)
Affinity DataKi:  0.170nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM30704((phenylmethyl) N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a...)
Affinity DataKi:  0.180nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50214298(CHEMBL93862)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]mesulergine from human cloned 5-hydroxytryptamine 2C receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50001786(1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]prozosin from human cloned 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50375451(CHEMBL408579)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]5-HT from human 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM84994(CAS_163091 | NSC_163091 | ORG-5222)
Affinity DataKi:  0.200nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50001775((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Affinity DataKi:  0.200nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50375457(CHEMBL261476)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]5-HT from human 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50115643((+/-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro...)
Affinity DataKi:  0.210nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2C receptor was determined using [3H]-mesulergineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50162957((11-Fluoro-2,3,3a,12b-tetrahydro-1-oxa-8-thia-dibe...)
Affinity DataKi:  0.210nMAssay Description:Inhibition of [3H]-mesulergine binding to human 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50001775((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Affinity DataKi:  0.25nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50098526(2-(8-Bromo-benzo[1,2-b;4,5-b']difuran-4-yl)-1-meth...)
Affinity DataKi:  0.25nMAssay Description:Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50001775((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Affinity DataKi:  0.25nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50214295(CHEMBL91221)
Affinity DataKi:  0.251nMAssay Description:Displacement of [3H]mesulergine from human cloned 5-hydroxytryptamine 2C receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50459718(CHEMBL4213379 | US10836764, Compound 106)
Affinity DataKi:  0.251nMAssay Description:Displacement of [125I]-DOI from recombinant human 5HT2CR transfected in human HEK293 cells incubated for 45 mins by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50098532(2-(8-Bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']d...)
Affinity DataKi:  0.260nMAssay Description:Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM84994(CAS_163091 | NSC_163091 | ORG-5222)
Affinity DataKi:  0.270nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50169264((4R,10aR)-7-Chloro-4,6-dimethyl-1,2,3,4,10,10a-hex...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity toward 5-HT2C receptor evaluated by displacement of [3H]-5-HT radioligand More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50169264((4R,10aR)-7-Chloro-4,6-dimethyl-1,2,3,4,10,10a-hex...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]-5HT from human recombinant 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50052337(2-(8-bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']d...)
Affinity DataKi:  0.300nMAssay Description:Binding activity against cloned human 5-hydroxytryptamine 2C receptor using [125I]-DOI as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50064703((R)-2-(8-Bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-...)
Affinity DataKi:  0.300nMAssay Description:Binding ability of compound at cloned human 5-hydroxytryptamine 2C receptor using [125 I]DOI as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50052337(2-(8-bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']d...)
Affinity DataKi:  0.300nMAssay Description:Agonistic activity at cloned human 5-hydroxytryptamine 2C receptor using [125I]-DOI as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50557505(CHEMBL4776557)
Affinity DataKi:  0.316nMAssay Description:Displacement of [125I]-DOI from recombinant human 5HT2CR transfected in human HEK293 cells incubated for 45 mins by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50206734(CHEMBL3959570)
Affinity DataKi:  0.316nMAssay Description:Displacement of [125I]DOI from recombinant human 5-HT2C receptor expressed in HEK293 cell membranes after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50002630(CHEMBL377174)
Affinity DataKi:  0.320nMAssay Description:Binding affinity to human 5HT2C receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50086063(5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-c...)
Affinity DataKi:  0.320nMAssay Description:Binding affinity towards human cloned 5-hydroxytryptamine receptor 2C in HEK293 cells, using [3H]mesulergine as radioligand.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM78940(METHIOTHEPIN | MLS000859918 | Methiothepin mesylat...)
Affinity DataKi:  0.340nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
Affinity DataKi:  0.380nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50115640((-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2...)
Affinity DataKi:  0.390nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2C receptor was determined using [3H]-mesulergineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50217990(CHEMBL54560)
Affinity DataKi:  0.398nMAssay Description:Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50206719(CHEMBL3956394)
Affinity DataKi:  0.398nMAssay Description:Displacement of [125I]DOI from recombinant human 5-HT2C receptor expressed in HEK293 cell membranes after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50471324(CHEMBL318639)
Affinity DataKi:  0.398nMAssay Description:Binding affinity against human 5-hydroxytryptamine 2C receptor using displacement of [3H]DOBMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50476485(CHEMBL234739)
Affinity DataKi:  0.398nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50206725(CHEMBL3947276)
Affinity DataKi:  0.398nMAssay Description:Displacement of [125I]DOI from recombinant human 5-HT2C receptor expressed in HEK293 cell membranes after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50218198(CHEMBL55914)
Affinity DataKi:  0.398nMAssay Description:In vitro binding affinity at human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by [3H]mesulergine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50008735((+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,...)
Affinity DataKi:  0.400nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50098530(1-Methyl-2-(8-trifluoromethyl-benzo[1,2-b;4,5-b']d...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50086073(5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-c...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity towards human cloned 5-hydroxytryptamine receptor 2C in HEK293 cells, using [3H]mesulergine as radioligand.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM35256((S)-mianserin | Lerivon | MIANSERIN | MIANSERIN (+...)
Affinity DataKi:  0.400nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50001775((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Affinity DataKi:  0.440nM ΔG°:  -49.6kJ/moleT: 2°CAssay Description:For the membrane binding, NIH-3T3 cells were grown to 70% confluence in 15-cm2 dishes and transfected with 10 ug of receptor plasmid DNA using Polyfe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM30704((phenylmethyl) N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a...)
Affinity DataKi:  0.470nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM85097(CAS_181632-25-7 | CHEMBL14563 | SB 242084)
Affinity DataKi:  0.480nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50086068(5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-c...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity towards human cloned 5-hydroxytryptamine receptor 2C in HEK293 cells, using [3H]mesulergine as radioligand.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50086246(CHEMBL3425758)
Affinity DataKi:  0.5nMAssay Description:Inhibition of Cy3B conjugated serotonin analogue binding to human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cell membranes after 60 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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