Found 11 hits of kon data for polymerid = 1043,1045,1064,236,3619,3621,50000072,50006539,50006985,50007874,1043,1045,1064,236,3619 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Acetylcholinesterase
(Bos taurus (bovine)) | BDBM50093799
((R)-1-Amino-13-eth-(E)-ylidene-8,8,11-trimethyl-6-...)Show SMILES C\C=C1/C2C=C(C)C[C@]1(N)c1ccc(=O)[nH]c1C2(C)C Show InChI InChI=1S/C17H22N2O/c1-5-11-13-8-10(2)9-17(11,18)12-6-7-14(20)19-15(12)16(13,3)4/h5-8,13H,9,18H2,1-4H3,(H,19,20)/b11-5+/t13?,17-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | n/a | n/a | n/a | n/a | 0.0130 | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Dissociation constant for the inhibition of fetal bovine serum acetylcholinesterase was determined.. |
Bioorg Med Chem Lett 6: 259-262 (1996)
Article DOI: 10.1016/0960-894X(96)00012-1
BindingDB Entry DOI: 10.7270/Q2R49R8X |
More data for this
Ligand-Target Pair | |
Acetylcholinesterase
(Bos taurus (bovine)) | BDBM50342601
(CHEMBL1255901 | Huperzine A)Show SMILES C\C=C1/[C@@H]2Cc3[nH]c(=O)ccc3[C@]1(N)CC(C)=C2 Show InChI InChI=1S/C15H18N2O/c1-3-11-10-6-9(2)8-15(11,16)12-4-5-14(18)17-13(12)7-10/h3-6,10H,7-8,16H2,1-2H3,(H,17,18)/b11-3+/t10-,15-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | n/a | n/a | n/a | 0.000367 | 0.0155 | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Dissociation constant for the inhibition of fetal bovine serum acetylcholinesterase was determined.. |
Bioorg Med Chem Lett 6: 259-262 (1996)
Article DOI: 10.1016/0960-894X(96)00012-1
BindingDB Entry DOI: 10.7270/Q2R49R8X |
More data for this
Ligand-Target Pair | |
Acetylcholinesterase
(Bos taurus (bovine)) | BDBM50342601
(CHEMBL1255901 | Huperzine A)Show SMILES C\C=C1/[C@@H]2Cc3[nH]c(=O)ccc3[C@]1(N)CC(C)=C2 Show InChI InChI=1S/C15H18N2O/c1-3-11-10-6-9(2)8-15(11,16)12-4-5-14(18)17-13(12)7-10/h3-6,10H,7-8,16H2,1-2H3,(H,17,18)/b11-3+/t10-,15-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | n/a | n/a | n/a | n/a | 0.0155 | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Kinetic constant for inhibition of fetal bovine serum acetylcholinesterase |
Bioorg Med Chem Lett 6: 259-262 (1996)
Article DOI: 10.1016/0960-894X(96)00012-1
BindingDB Entry DOI: 10.7270/Q2R49R8X |
More data for this
Ligand-Target Pair | |
Acetylcholinesterase
(Bos taurus (bovine)) | BDBM50342601
(CHEMBL1255901 | Huperzine A)Show SMILES C\C=C1/[C@@H]2Cc3[nH]c(=O)ccc3[C@]1(N)CC(C)=C2 Show InChI InChI=1S/C15H18N2O/c1-3-11-10-6-9(2)8-15(11,16)12-4-5-14(18)17-13(12)7-10/h3-6,10H,7-8,16H2,1-2H3,(H,17,18)/b11-3+/t10-,15-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | n/a | n/a | n/a | n/a | 0.0567 | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Kinetic constant for inhibition of fetal bovine serum acetylcholinesterase |
Bioorg Med Chem Lett 6: 259-262 (1996)
Article DOI: 10.1016/0960-894X(96)00012-1
BindingDB Entry DOI: 10.7270/Q2R49R8X |
More data for this
Ligand-Target Pair | |
Acetylcholinesterase
(Homo sapiens (Human)) | BDBM50027340
(FENAMIPHOS)Show InChI InChI=1S/C13H22NO3PS/c1-6-17-18(15,16)14(10(2)3)12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,15,16) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | n/a | n/a | 0.330 | n/a | n/a |
Universit£ di Siena
Curated by ChEMBL
| Assay Description
Inhibition of human AChE |
J Med Chem 51: 3154-70 (2008)
Article DOI: 10.1021/jm701253t
BindingDB Entry DOI: 10.7270/Q22Z16D4 |
More data for this
Ligand-Target Pair | |
Acetylcholinesterase
(Homo sapiens (Human)) | BDBM50027341
(CHEBI:38721 | METHAMIDOPHOS)Show InChI InChI=1S/C2H8NO2PS/c1-5-6(3,4)7-2/h1-2H3,(H2,3,4) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
| Purchase
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | n/a | n/a | 32 | n/a | n/a |
Universit£ di Siena
Curated by ChEMBL
| Assay Description
Inhibition of human AChE |
J Med Chem 51: 3154-70 (2008)
Article DOI: 10.1021/jm701253t
BindingDB Entry DOI: 10.7270/Q22Z16D4 |
More data for this
Ligand-Target Pair | |
Acetylcholinesterase
(Homo sapiens (Human)) | BDBM50022772
(CHEMBL1025 | Diisopropoxyphosphoryl fluoride | Dii...)Show InChI InChI=1S/C6H14FO3P/c1-5(2)9-11(7,8)10-6(3)4/h5-6H,1-4H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
| Purchase
CHEBI
CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem
Patents
| DrugBank
Article
PubMed
| n/a | n/a | n/a | n/a | n/a | n/a | 2.17E+3 | n/a | n/a |
Universit£ di Siena
Curated by ChEMBL
| Assay Description
Inhibition of human AChE |
J Med Chem 51: 3154-70 (2008)
Article DOI: 10.1021/jm701253t
BindingDB Entry DOI: 10.7270/Q22Z16D4 |
More data for this
Ligand-Target Pair | |
Acetylcholinesterase
(Bos taurus (bovine)) | BDBM50027343
(CHEBI:75701 | ISOPROPYL METHYLPHOSPHONOFLUORIDATE)Show InChI InChI=1S/C4H10FO2P/c1-4(2)7-8(3,5)6/h4H,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | n/a | n/a | 1.23E+4 | n/a | n/a |
Universit£ di Siena
Curated by ChEMBL
| Assay Description
Inhibition of bovine AChE |
J Med Chem 51: 3154-70 (2008)
Article DOI: 10.1021/jm701253t
BindingDB Entry DOI: 10.7270/Q22Z16D4 |
More data for this
Ligand-Target Pair | |
Acetylcholinesterase
(Bos taurus (bovine)) | BDBM50027342
(CHEMBL483105)Show InChI InChI=1S/C11H26NO2PS/c1-7-14-15(6,13)16-9-8-12(10(2)3)11(4)5/h10-11H,7-9H2,1-6H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | n/a | n/a | 1.10E+5 | n/a | n/a |
Universit£ di Siena
Curated by ChEMBL
| Assay Description
Inhibition of bovine AChE |
J Med Chem 51: 3154-70 (2008)
Article DOI: 10.1021/jm701253t
BindingDB Entry DOI: 10.7270/Q22Z16D4 |
More data for this
Ligand-Target Pair | |
Acetylcholinesterase
(Homo sapiens (Human)) | BDBM50027343
(CHEBI:75701 | ISOPROPYL METHYLPHOSPHONOFLUORIDATE)Show InChI InChI=1S/C4H10FO2P/c1-4(2)7-8(3,5)6/h4H,1-3H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | n/a | n/a | 4.50E+5 | n/a | n/a |
Universit£ di Siena
Curated by ChEMBL
| Assay Description
Inhibition of human AChE |
J Med Chem 51: 3154-70 (2008)
Article DOI: 10.1021/jm701253t
BindingDB Entry DOI: 10.7270/Q22Z16D4 |
More data for this
Ligand-Target Pair | |
Acetylcholinesterase
(Homo sapiens (Human)) | BDBM50027342
(CHEMBL483105)Show InChI InChI=1S/C11H26NO2PS/c1-7-14-15(6,13)16-9-8-12(10(2)3)11(4)5/h10-11H,7-9H2,1-6H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | n/a | n/a | 2.00E+6 | n/a | n/a |
Universit£ di Siena
Curated by ChEMBL
| Assay Description
Inhibition of human AChE |
J Med Chem 51: 3154-70 (2008)
Article DOI: 10.1021/jm701253t
BindingDB Entry DOI: 10.7270/Q22Z16D4 |
More data for this
Ligand-Target Pair | |
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