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Found 511 Enz. Inhib. hit(s) with Target = 'Integrin alpha-4/beta-7'
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50535742(CHEMBL4592659)
Affinity DataEC50:  1.40nMAssay Description:Antagonist activity at integrin alpha4beta7 expressed in human RPMI8866 cells assessed as reduction in cell adhesion to rat MadCAM incubated for 40 t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50433575(CHEMBL2381700)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437654(CHEMBL2408072)
Affinity DataIC50:  4.55E+3nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437655(CHEMBL2407890)
Affinity DataIC50:  3.68E+3nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437658(CHEMBL2407877)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437642(CHEMBL2407884)
Affinity DataIC50:  1.37E+3nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437647(CHEMBL2407886)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437656(CHEMBL2407888)
Affinity DataIC50:  594nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437646(CHEMBL2407881)
Affinity DataIC50:  510nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437640(CHEMBL1684983)
Affinity DataIC50:  510nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437641(CHEMBL2407885)
Affinity DataIC50:  483nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437639(CHEMBL2407887)
Affinity DataIC50:  468nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437643(CHEMBL2408071)
Affinity DataIC50:  419nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437648(CHEMBL2407879)
Affinity DataIC50:  321nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437670(CHEMBL2407876)
Affinity DataIC50:  311nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437661(CHEMBL2407882)
Affinity DataIC50:  262nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437650(CHEMBL2407883)
Affinity DataIC50:  223nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437649(CHEMBL2408070)
Affinity DataIC50:  217nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437644(CHEMBL2407880)
Affinity DataIC50:  179nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437651(CHEMBL2408068)
Affinity DataIC50:  174nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437645(CHEMBL2407878)
Affinity DataIC50:  156nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437659(CHEMBL2407889)
Affinity DataIC50:  151nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437666(CHEMBL2408055)
Affinity DataIC50:  104nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437657(CHEMBL2408067)
Affinity DataIC50:  67nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437672(CHEMBL2408060)
Affinity DataIC50:  62nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437669(CHEMBL2408056)
Affinity DataIC50:  55nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437671(CHEMBL2408057)
Affinity DataIC50:  50nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437663(CHEMBL2408059)
Affinity DataIC50:  36nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437668(CHEMBL2407099)
Affinity DataIC50:  31nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437673(CHEMBL2407892)
Affinity DataIC50:  30nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437652(CHEMBL2408069)
Affinity DataIC50:  29nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437660(CHEMBL2408058)
Affinity DataIC50:  29nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437664(CHEMBL2408063)
Affinity DataIC50:  14nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437665(CHEMBL2408065)
Affinity DataIC50:  12nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437662(CHEMBL2408061)
Affinity DataIC50:  12nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437667(CHEMBL2408064)
Affinity DataIC50:  6nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437675(CHEMBL2408062)
Affinity DataIC50:  4nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50437674(CHEMBL2408066)
Affinity DataIC50:  3nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM16801((2S)-2-[(2,6-dichlorophenyl)formamido]-3-[4-(2,6-d...)
Affinity DataIC50:  58nMT: 2°CAssay Description:M2 anti-FLAG antibody coated 96-well plates were coated with recombinant FLAG-hMAdCAM-1 contained in Dulbecco PBS. The compounds to be tested were ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM16802((2S)-2-[(2,6-dichlorophenyl)formamido]-3-[4-(5-met...)
Affinity DataIC50:  3nMT: 2°CAssay Description:M2 anti-FLAG antibody coated 96-well plates were coated with recombinant FLAG-hMAdCAM-1 contained in Dulbecco PBS. The compounds to be tested were ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM16803((2R)-2-[(2,6-dichlorophenyl)formamido]-3-[4-(5-met...)
Affinity DataIC50:  170nMT: 2°CAssay Description:M2 anti-FLAG antibody coated 96-well plates were coated with recombinant FLAG-hMAdCAM-1 contained in Dulbecco PBS. The compounds to be tested were ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM16804((2S)-2-[(2,6-dichlorophenyl)formamido]-3-[4-(5-met...)
Affinity DataIC50:  41nMT: 2°CAssay Description:M2 anti-FLAG antibody coated 96-well plates were coated with recombinant FLAG-hMAdCAM-1 contained in Dulbecco PBS. The compounds to be tested were ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM16805((2S)-3-[4-(2-benzyl-5-methoxy-3-oxo-2,3-dihydropyr...)
Affinity DataIC50:  100nMT: 2°CAssay Description:M2 anti-FLAG antibody coated 96-well plates were coated with recombinant FLAG-hMAdCAM-1 contained in Dulbecco PBS. The compounds to be tested were ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM16806((2S)-2-[(2,6-dichlorophenyl)formamido]-3-[4-(5-met...)
Affinity DataIC50:  18nMT: 2°CAssay Description:M2 anti-FLAG antibody coated 96-well plates were coated with recombinant FLAG-hMAdCAM-1 contained in Dulbecco PBS. The compounds to be tested were ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM16807((2S)-3-[4-(2-cyclohexyl-5-methoxy-3-oxo-2,3-dihydr...)
Affinity DataIC50:  330nMT: 2°CAssay Description:M2 anti-FLAG antibody coated 96-well plates were coated with recombinant FLAG-hMAdCAM-1 contained in Dulbecco PBS. The compounds to be tested were ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM16808((2S)-3-[4-(2-tert-butyl-5-methoxy-3-oxo-2,3-dihydr...)
Affinity DataIC50:  42nMT: 2°CAssay Description:M2 anti-FLAG antibody coated 96-well plates were coated with recombinant FLAG-hMAdCAM-1 contained in Dulbecco PBS. The compounds to be tested were ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM16809((2S)-2-[(2,6-dichlorophenyl)formamido]-3-{4-[2-(2-...)
Affinity DataIC50:  2nMT: 2°CAssay Description:M2 anti-FLAG antibody coated 96-well plates were coated with recombinant FLAG-hMAdCAM-1 contained in Dulbecco PBS. The compounds to be tested were ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM16810((2S)-2-[(2,6-dichlorophenyl)formamido]-3-(4-{5-met...)
Affinity DataIC50:  2nMT: 2°CAssay Description:M2 anti-FLAG antibody coated 96-well plates were coated with recombinant FLAG-hMAdCAM-1 contained in Dulbecco PBS. The compounds to be tested were ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM16811((2S)-2-[(2,6-dichlorophenyl)formamido]-3-[4-(5-hyd...)
Affinity DataIC50:  49nMT: 2°CAssay Description:M2 anti-FLAG antibody coated 96-well plates were coated with recombinant FLAG-hMAdCAM-1 contained in Dulbecco PBS. The compounds to be tested were ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM16812((2S)-2-[(2,6-dichlorophenyl)formamido]-3-[4-(5-eth...)
Affinity DataIC50:  2nMT: 2°CAssay Description:M2 anti-FLAG antibody coated 96-well plates were coated with recombinant FLAG-hMAdCAM-1 contained in Dulbecco PBS. The compounds to be tested were ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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