Affinity DataEC50: 55nMAssay Description:Activation of human metabotropic glutamate 6 receptor expressed in golden hamster AV12-664 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 55nMAssay Description:Metabotropic glutamate receptor 6 agonist activity to influence forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 147nMAssay Description:Metabotropic glutamate receptor 6 agonist activity to influence forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 280nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
Affinity DataEC50: 340nMAssay Description:Activity at rat recombinant mGluR6 expressed in CHO cells assessed as cAMP productionMore data for this Ligand-Target Pair
Affinity DataEC50: 340nMAssay Description:Activity at rat mGluR6 by measuring cAMP formation in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 401nMAssay Description:Inhibition of forskolin stimulated cAMP production in RGT cells expressingrecombinant human mGluR6More data for this Ligand-Target Pair
Affinity DataEC50: 490nMAssay Description:Agonist activity at rat mGlu6 receptor expressed in HEK293 cells assessed as IP1 accumulation by IP-One functional assayMore data for this Ligand-Target Pair
Affinity DataEC50: 570nMAssay Description:Effect on Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
Affinity DataEC50: 600nMAssay Description:Metabotropic glutamate receptor 6 agonist activity to influence forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 709nMAssay Description:Agonist activity at human mGlu6 receptor expressed in golden Syrian hamster AV12 cells coexpressing EAAT1 after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 730nMAssay Description:Agonist activity at rat mGluR6 receptor expressed HEK293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
Affinity DataEC50: 760nMAssay Description:Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
Affinity DataEC50: 780nMAssay Description:Agonist activity at human mGlu6 receptor expressed in golden Syrian hamster AV12 cells coexpressing EAAT1 after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 900nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR6 in ratMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at mGlu6 receptor (unknown origin) expressed in human Flp-In-T-REx-293 cells by luciferase based GloSensor cAMP AssayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist activity at rat mGlu6 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Tested for the agonistic activity against Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
Affinity DataEC50: 1.03E+3nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.07E+3nMAssay Description:Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
Affinity DataEC50: 1.10E+3nMAssay Description:Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
Affinity DataEC50: 1.10E+3nMAssay Description:Agonist activity at rat mGlu6 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+3nMAssay Description:Metabotropic glutamate receptor 6 agonist activity to influence forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.27E+3nMAssay Description:Agonist activity at human mGlu6 receptor expressed in golden Syrian hamster AV12 cells coexpressing EAAT1 after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.41E+3nMAssay Description:Agonist activity at human mGlu6 receptor expressed in golden Syrian hamster AV12 cells coexpressing EAAT1 after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.70E+3nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
Affinity DataEC50: 1.91E+3nMAssay Description:Agonist activity at rat mGlu6 receptor expressed in HEK293 cells assessed as IP1 accumulation by IP-One functional assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.95E+3nMAssay Description:Agonist activity at mGlu6 receptor expressed in HEK 293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
Affinity DataEC50: 1.95E+3nMAssay Description:Agonist activity at human mGlu6 receptor expressed in hamster AV12 cells co-expressing rat EAAT1 assessed as inhibition of forskolin-stimulated cAMP ...More data for this Ligand-Target Pair
Affinity DataEC50: 2.08E+3nMAssay Description:Agonist activity at rat mGluR6 receptor expressed HEK293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
Affinity DataEC50: 2.40E+3nMAssay Description:Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
Affinity DataEC50: 2.40E+3nMAssay Description:Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
Affinity DataEC50: 2.40E+3nMAssay Description:Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
Affinity DataEC50: 2.43E+3nMAssay Description:Inhibition of forskolin stimulated cAMP production in RGT cells expressingrecombinant human mGluR6More data for this Ligand-Target Pair
Affinity DataEC50: 2.50E+3nMAssay Description:Metabotropic glutamate receptors were transiently transfected in HEK293 cells by electroporation as described elsewhere (Brabet I. et al., 1998) and ...More data for this Ligand-Target Pair
Affinity DataEC50: 2.70E+3nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR6 in ratMore data for this Ligand-Target Pair
Affinity DataEC50: 2.90E+3nMAssay Description:Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
Affinity DataEC50: 2.99E+3nMAssay Description:Inhibition of forskolin stimulated cAMP production in RGT cells expressingrecombinant human mGluR6More data for this Ligand-Target Pair
Affinity DataEC50: 3.20E+3nMAssay Description:Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
Affinity DataEC50: 3.20E+3nMAssay Description:Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
Affinity DataEC50: 3.20E+3nMAssay Description:Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
Affinity DataEC50: 3.20E+3nMAssay Description:Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
Affinity DataEC50: 3.25E+3nMAssay Description:Agonist activity at human mGlu6 receptor expressed in golden Syrian hamster AV12 cells coexpressing EAAT1 after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.30E+3nMAssay Description:Agonist activity at rat mGlu6 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
Affinity DataEC50: 3.36E+3nMAssay Description:Agonist activity at human mGlu6 receptor expressed in golden Syrian hamster AV12 cells coexpressing EAAT1 after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.41E+3nMAssay Description:Agonist activity at mGlu6 receptor expressed in HEK 293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
Affinity DataEC50: 3.45E+3nMAssay Description:Agonist activity at rat mGluR6 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.45E+3nMAssay Description:Agonist activity at human recombinant mGlu6 receptor expressed in AV12 cells assessed as inhibition of forskolin-stimulated cAMP production after 1 h...More data for this Ligand-Target Pair
Affinity DataEC50: 3.60E+3nMAssay Description:Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair