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Found 214 Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 1'
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118215(CHEMBL1628528 | Ip5I)
Affinity DataEC50:  1.5nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 1 (P2X1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118219(Bz-ATP | CHEMBL339386)
Affinity DataEC50:  2nMAssay Description:The compound was evaluated for antagonist activity against recombinant human P2X purinoceptor 1 (P2X1 )More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118222(MRS 2257)
Affinity DataEC50:  5nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 1 (P2X1) at 1 uM,expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50370141(TNP-ATP)
Affinity DataEC50:  6nMAssay Description:The compound was evaluated for antagonist activity against recombinant human P2X purinoceptor 1 (P2X1 )More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118244(CHEMBL131091 | PPNDS)
Affinity DataEC50:  14nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 1 (P2X1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50064800(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataEC50:  43nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 1 (P2X1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118232(2-MeSATP | ATP, 2-meS | CHEMBL336208)
Affinity DataEC50:  54nMAssay Description:The compound was evaluated for antagonist activity against recombinant human P2X purinoceptor 1 (P2X1 )More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50366480(ADENOSINE TRIPHOSPHATE | ATP)
Affinity DataEC50:  56nMAssay Description:The compound was evaluated for antagonist activity against recombinant human P2X purinoceptor 1 (P2X1 )More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118226(CHEMBL337062 | PAPET-ATP)
Affinity DataEC50:  98nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 1 (P2X1) at 1 uM,expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)
Affinity DataEC50:  99nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 1 (P2X1) at 1 uM,expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118220((ppA)2 | A(5')p4(5')A | CHEMBL339385 | P(1),P(4)-b...)
Affinity DataEC50:  182nMAssay Description:The compound was evaluated for antagonist activity against recombinant human P2X purinoceptor 1 (P2X1 )More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118221(9H-purine derivative | CHEMBL132722 | DIPHOSPHOMET...)
Affinity DataEC50:  200nMAssay Description:The compound was evaluated for antagonist activity against recombinant human P2X purinoceptor 1 (P2X1 )More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118240(((2R,3S,4R,5R)-5-(6-amino-2-(hexylthio)-9H-purin-9...)
Affinity DataEC50:  840nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 1 (P2X1) at 1 uM,expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50336799(5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino...)
Affinity DataEC50:  1.00E+3nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 1 (P2X1) at 1 uM,expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118229(CHEMBL129841 | MRS 2179)
Affinity DataEC50:  1.15E+3nMAssay Description:The compound was evaluated for antagonist activity against recombinant human P2X purinoceptor 1 (P2X1 )More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50370142(CHEMBL133463)
Affinity DataEC50:  2.00E+3nMAssay Description:The compound was evaluated for antagonist activity against recombinant human P2X purinoceptor 1 (P2X1 )More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118217(ADENOSINE-5'-DIPHOSPHATE MONOTHIOPHOSPHATE | ATP-g...)
Affinity DataEC50:  2.30E+3nMAssay Description:The compound was evaluated for antagonist activity against recombinant human P2X purinoceptor 1 (P2X1 )More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118230(5'-O-[(R)-HYDROXY(THIOPHOSPHONOOXY)PHOSPHORYL]ADEN...)
Affinity DataEC50:  2.50E+3nMAssay Description:The compound was evaluated for antagonist activity against recombinant human P2X purinoceptor 1 (P2X1 )More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118216((4-formyl-5-hydroxy-6-methylpyridin-3-yl)methyl di...)
Affinity DataEC50:  3.00E+3nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 1 (P2X1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50064803(3-Methyl-7-oxo-5,9-dihydro-6,8-dioxa-2-aza-7lambda...)
Affinity DataEC50:  5.90E+3nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50064803(3-Methyl-7-oxo-5,9-dihydro-6,8-dioxa-2-aza-7lambda...)
Affinity DataEC50:  5.90E+3nMAssay Description:Compound was tested in a functional ion channel assay of ATP-induced current at recombinant rat P2X1 receptor expressed in Xenopus oocytes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50368125(ADENOSINE DIPHOSPHATE | ADP)
Affinity DataEC50:  1.00E+4nMAssay Description:The compound was evaluated for antagonist activity against recombinant human P2X purinoceptor 1 (P2X1 )More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50064803(3-Methyl-7-oxo-5,9-dihydro-6,8-dioxa-2-aza-7lambda...)
Affinity DataEC50:  1.02E+4nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 1 (P2X1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50594505(CHEMBL5177316)
Affinity DataEC50: <1.00E+5nMAssay Description:Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50594506(CHEMBL5183218)
Affinity DataEC50: <1.00E+5nMAssay Description:Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50000029(4-Methyl-8-{4-methyl-3-[3-(3-{3-[2-methyl-5-(4,6,8...)
Affinity DataKi:  50nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM85682(CAS_5311315 | NF279 | NSC_5311315)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM85682(CAS_5311315 | NF279 | NSC_5311315)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM85730(CAS_5311313 | NF023 | NSC_5311313)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50171290(5-(4-Bromo-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM21280(5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)met...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50000029(4-Methyl-8-{4-methyl-3-[3-(3-{3-[2-methyl-5-(4,6,8...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015276(CHEMBL3263056 | US9428504, 166 | US9428504, 167)
Affinity DataIC50:  180nMAssay Description:Antagonist activity at P2X1 receptor (unknown origin) by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50064801(2-(4,7-Dihydroxy-3-methyl-7-oxo-5,9-dihydro-6,8-di...)
Affinity DataIC50:  1.02E+4nMAssay Description:Compound was tested in a functional ion channel assay of ATP-induced current at recombinant rat P2X1 receptor expressed in Xenopus oocytes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50064800(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50:  4.25E+4nMAssay Description:Compound was tested in a functional ion channel assay of ATP-induced current at recombinant rat P2X1 receptor expressed in Xenopus oocytes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)
Affinity DataIC50:  9.85E+4nMAssay Description:Compound was tested in a functional ion channel assay of ATP-induced current at recombinant rat P2X1 receptor expressed in Xenopus oocytes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50064801(2-(4,7-Dihydroxy-3-methyl-7-oxo-5,9-dihydro-6,8-di...)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50102296(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonomethyl-p...)
Affinity DataIC50:  37nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50102295(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50:  9.40nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50102299(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonomethyl-p...)
Affinity DataIC50:  11nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50102298(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonomethyl-p...)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)
Affinity DataIC50:  99nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50102300(CHEMBL331250 | [4-(4-Formyl-5-hydroxy-6-methyl-3-p...)
Affinity DataIC50:  12nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50064800(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50:  43nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50102297(CHEMBL118007 | [2-(3,5-Bis-phosphonomethyl-phenyla...)
Affinity DataIC50:  42nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50102304(CHEMBL116926 | Phosphoric acid mono-(4-formyl-5-hy...)
Affinity DataIC50:  42nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50102301(4-[4-Formyl-5-hydroxy-6-methyl-3-(2-phosphono-ethy...)
Affinity DataIC50:  20nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118231(CHEMBL134193 | Cibachron Blue 3GA)
Affinity DataIC50:  9.60E+3nMAssay Description:The compound was evaluated for antagonist activity against P2X purinoceptor 1 (P2X1) from rat vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118237(CHEMBL130059 | Uniblue A)
Affinity DataIC50:  7.50E+3nMAssay Description:The compound was evaluated for antagonist activity against P2X purinoceptor 1 (P2X1) from rat vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50168286(1H-Benzoimidazole-2-carboxylic acid [(R)-1-((1S,2R...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibitory concentration against human P2X purinoreceptor 1 (hP2X1) expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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