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Found 291 Enz. Inhib. hit(s) with Target = '4-hydroxyphenylpyruvate dioxygenase'
Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Universit£

Curated by ChEMBL
LigandPNGBDBM50403921(CHEMBL309664)
Affinity DataIC50:  15nMAssay Description:Inhibition of pig liver HPPD using 4-hydroxyphenylpyruvic acid as substrate after 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Arabidopsis thaliana)
Universit£

Curated by ChEMBL
LigandPNGBDBM50264344(CHEMBL4082652)
Affinity DataIC50:  19nMAssay Description:Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli JM105 using 4-HPP as substrate preincubated for 15 mins followed by substrate a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Universit£

Curated by ChEMBL
LigandPNGBDBM50403921(CHEMBL309664)
Affinity DataIC50:  20nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Universit£

Curated by ChEMBL
LigandPNGBDBM50403921(CHEMBL309664)
Affinity DataIC50:  20nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50072265(CHEMBL3408320)
Affinity DataIC50:  21nMAssay Description:Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50072264(CHEMBL3408319)
Affinity DataIC50:  22nMAssay Description:Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50072237(CHEMBL3408314)
Affinity DataIC50:  22nMAssay Description:Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Universit£

Curated by ChEMBL
LigandPNGBDBM50403929(CHEMBL76394)
Affinity DataIC50:  28nMAssay Description:Inhibition of pig liver HPPD using 4-hydroxyphenylpyruvic acid as substrate after 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Universit£

Curated by ChEMBL
LigandPNGBDBM50403929(CHEMBL76394)
Affinity DataIC50:  30nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Universit£

Curated by ChEMBL
LigandPNGBDBM50089165(CHEMBL23622 | Cyclopropanecarboxylic acid 3-oxo-cy...)
Affinity DataIC50:  30nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Universit£

Curated by ChEMBL
LigandPNGBDBM50089165(CHEMBL23622 | Cyclopropanecarboxylic acid 3-oxo-cy...)
Affinity DataIC50:  30nMAssay Description:Inhibition of pig liver HPPD using 4-hydroxyphenylpyruvic acid as substrate after 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Universit£

Curated by ChEMBL
LigandPNGBDBM50089165(CHEMBL23622 | Cyclopropanecarboxylic acid 3-oxo-cy...)
Affinity DataIC50:  30nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Universit£

Curated by ChEMBL
LigandPNGBDBM50089165(CHEMBL23622 | Cyclopropanecarboxylic acid 3-oxo-cy...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibitory concentration required against 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) taken from pig liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Universit£

Curated by ChEMBL
LigandPNGBDBM50403929(CHEMBL76394)
Affinity DataIC50:  30nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Universit£

Curated by ChEMBL
LigandPNGBDBM50089165(CHEMBL23622 | Cyclopropanecarboxylic acid 3-oxo-cy...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibitory activity of the compound against HPPD(4-hydroxyphenylpyruvate Dioxygenase) from pig liver using enol borate assay methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50264347(CHEMBL4092919)
Affinity DataIC50:  36nMAssay Description:Inhibition of Wistar rat liver cytosol HPPD using HPP as substrate assessed as reduction in O2 consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Arabidopsis thaliana)
Universit£

Curated by ChEMBL
LigandPNGBDBM50487120(CHEMBL2251430)
Affinity DataIC50:  36nMAssay Description:Inhibition of Arabidopsis thaliana 4-hydroxyphenylpyruvate dioxygenaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50264337(CHEBI:38321 | MESOTRIONE)
Affinity DataIC50:  37nMAssay Description:Inhibition of Wistar rat liver cytosol HPPD using HPP as substrate assessed as reduction in O2 consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50072269(CHEMBL3408324)
Affinity DataIC50:  39nMAssay Description:Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Universit£

Curated by ChEMBL
LigandPNGBDBM50124366(4-Cyclopropanecarbonyl-3-cyclopropanecarbonyloxy-5...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibitory concentration required against 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) taken from pig liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Universit£

Curated by ChEMBL
LigandPNGBDBM50075319(2-{HYDROXY[2-NITRO-4-(TRIFLUOROMETHYL)PHENYL]METHY...)
Affinity DataIC50:  40nMAssay Description:Inhibition of pig liver 4-Hydroxyphenylpyruvate dioxygenase (4-HPPD) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Universit£

Curated by ChEMBL
LigandPNGBDBM50075319(2-{HYDROXY[2-NITRO-4-(TRIFLUOROMETHYL)PHENYL]METHY...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibitory activity of the compound against HPPD(4-hydroxyphenylpyruvate Dioxygenase) from pig liver using enol borate assay methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Universit£

Curated by ChEMBL
LigandPNGBDBM50088804(1,3-Cyclohexanedione, 2-(2-nitro-4-(trifluoromethy...)
Affinity DataIC50:  40nMAssay Description:Inhibition of 4-hydroxyphenylpyruvate dioxygenase of purified pig liver by enol-borate methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Universit£

Curated by ChEMBL
LigandPNGBDBM50075319(2-{HYDROXY[2-NITRO-4-(TRIFLUOROMETHYL)PHENYL]METHY...)
Affinity DataIC50:  40nMAssay Description:The inhibitory activity of the compound on pig liver 4-hydroxyphenylpyruvate dioxygenase (HPPD) was evaluated.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Universit£

Curated by ChEMBL
LigandPNGBDBM50075319(2-{HYDROXY[2-NITRO-4-(TRIFLUOROMETHYL)PHENYL]METHY...)
Affinity DataIC50:  40nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Universit£

Curated by ChEMBL
LigandPNGBDBM50124366(4-Cyclopropanecarbonyl-3-cyclopropanecarbonyloxy-5...)
Affinity DataIC50:  40nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50088804(1,3-Cyclohexanedione, 2-(2-nitro-4-(trifluoromethy...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Wistar rat liver cytosol HPPD using HPP as substrate assessed as reduction in O2 consumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50088804(1,3-Cyclohexanedione, 2-(2-nitro-4-(trifluoromethy...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Wistar rat liver HPPD using 4-Hydroxyphenylpyruvate as substrate assessed as reduction in oxygen consumption preincubated for 3 mins fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Universit£

Curated by ChEMBL
LigandPNGBDBM50124366(4-Cyclopropanecarbonyl-3-cyclopropanecarbonyloxy-5...)
Affinity DataIC50:  40nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Universit£

Curated by ChEMBL
LigandPNGBDBM50075319(2-{HYDROXY[2-NITRO-4-(TRIFLUOROMETHYL)PHENYL]METHY...)
Affinity DataIC50:  40nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50072270(CHEMBL3408325)
Affinity DataIC50:  40nMAssay Description:Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Arabidopsis thaliana)
Universit£

Curated by ChEMBL
LigandPNGBDBM50487119(CHEMBL2251439)
Affinity DataIC50:  43nMAssay Description:Inhibition of Arabidopsis thaliana 4-hydroxyphenylpyruvate dioxygenaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Universit£

Curated by ChEMBL
LigandPNGBDBM50075318(2-(2-Chloro-4-methanesulfonyl-benzoyl)-3-hydroxy-c...)
Affinity DataIC50:  45nMAssay Description:Inhibitory activity of the compound on pig liver 4-hydroxyphenylpyruvate dioxygenase (HPPD) was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Universit£

Curated by ChEMBL
LigandPNGBDBM50075318(2-(2-Chloro-4-methanesulfonyl-benzoyl)-3-hydroxy-c...)
Affinity DataIC50:  45nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50536974(CHEMBL4533679)
Affinity DataIC50:  47nMAssay Description:Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Arabidopsis thaliana)
Universit£

Curated by ChEMBL
LigandPNGBDBM50487126(CHEMBL2251437)
Affinity DataIC50:  48nMAssay Description:Inhibition of Arabidopsis thaliana 4-hydroxyphenylpyruvate dioxygenaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Universit£

Curated by ChEMBL
LigandPNGBDBM50075318(2-(2-Chloro-4-methanesulfonyl-benzoyl)-3-hydroxy-c...)
Affinity DataIC50:  50nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50072230(CHEMBL3408157)
Affinity DataIC50:  59nMAssay Description:Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50072236(CHEMBL3408313)
Affinity DataIC50:  61nMAssay Description:Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50536949(CHEMBL4526579)
Affinity DataIC50:  63nMAssay Description:Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50072266(CHEMBL3408321)
Affinity DataIC50:  64nMAssay Description:Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50536973(CHEMBL4582009)
Affinity DataIC50:  68nMAssay Description:Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50072223(CHEMBL3408156)
Affinity DataIC50:  68nMAssay Description:Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50536950(CHEMBL4564855)
Affinity DataIC50:  68nMAssay Description:Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Universit£

Curated by ChEMBL
LigandPNGBDBM50403933(CHEMBL72081)
Affinity DataIC50:  70nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Arabidopsis thaliana)
Universit£

Curated by ChEMBL
LigandPNGBDBM50056923((+)-usnic acid | (9bR)-2,6-diacetyl-3,7,9-trihydro...)
Affinity DataIC50:  70nMAssay Description:Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli JM105 using HPPA as substrate after preincubated for 15 min followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Sus scrofa)
Universit£

Curated by ChEMBL
LigandPNGBDBM50403933(CHEMBL72081)
Affinity DataIC50:  70nMAssay Description:Inhibition of pig liver HPPD using 4-hydroxyphenylpyruvic acid as substrate after 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50536952(CHEMBL4571726)
Affinity DataIC50:  70nMAssay Description:Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50536946(CHEMBL4540372)
Affinity DataIC50:  70nMAssay Description:Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Arabidopsis thaliana)
Universit£

Curated by ChEMBL
LigandPNGBDBM50487132(CHEMBL2251438)
Affinity DataIC50:  71nMAssay Description:Inhibition of Arabidopsis thaliana 4-hydroxyphenylpyruvate dioxygenaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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