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Found 492 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 6'
TargetC-C chemokine receptor type 6(Macaca mulatta)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50463591(CHEMBL4248604)
Affinity DataIC50:  0.450nMAssay Description:Inhibition of monkey CCR6 expressed in CHO cells assessed as decrease in CCL20-induced reduction of forskolin-stimulated cAMP accumulation preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM172369(US9090596, 50)
Affinity DataIC50:  1.40nMAssay Description:The experiments were carried out on the FLIPR TETRA.RTM. platform from Molecular Devices. After the basal level had been read, the compounds were add...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM291181(6-chloro-2-hydroxy-N,N-dimethyl-3-(2-{[(5-methylfu...)
Affinity DataIC50:  1.60nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM172372(US9090596, 53)
Affinity DataIC50:  1.90nMAssay Description:The experiments were carried out on the FLIPR TETRA.RTM. platform from Molecular Devices. After the basal level had been read, the compounds were add...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM291172(2-hydroxy-N,N-dimethyl-3-(2-{[(5-methylfuran-2-yl)...)
Affinity DataIC50:  2nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM291172(2-hydroxy-N,N-dimethyl-3-(2-{[(5-methylfuran-2-yl)...)
Affinity DataIC50:  2.20nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM236791(US9388149, 22 | US9580412, Example 22)
Affinity DataIC50:  2.20nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM172342(US9090596, 22)
Affinity DataIC50:  3.40nMAssay Description:The experiments were carried out on the FLIPR TETRA.RTM. platform from Molecular Devices. After the basal level had been read, the compounds were add...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM172328(US9090596, 8)
Affinity DataIC50:  5.80nMAssay Description:The experiments were carried out on the FLIPR TETRA.RTM. platform from Molecular Devices. After the basal level had been read, the compounds were add...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM531207((R)-3-((3-chloro-2-hydroxyphenyl)amino)-4-((5,5-di...)
Affinity DataIC50:  6nMAssay Description:HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM531086((R)-6-chloro-3-((2-((2,2-dimethyl-1-phenylpropyl)a...)
Affinity DataIC50:  6nMAssay Description:HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM50463591(CHEMBL4248604)
Affinity DataIC50:  6nMAssay Description:Inhibition of human CCR6 expressed in CHO cells assessed as decrease in CCL20-induced reduction of forskolin-stimulated cAMP accumulation preincubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM236795(US9388149, 2 (Diastereoisomer 1) | US9388149, 2 (D...)
Affinity DataIC50:  6nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM236795(US9388149, 2 (Diastereoisomer 1) | US9388149, 2 (D...)
Affinity DataIC50:  8nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM531125((R)-3-((2-((5,5-dimethyl-4,5,6,7-tetrahydrobenzofu...)
Affinity DataIC50:  8nMAssay Description:HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM236789(US9388149, 20 | US9580412, Example 20)
Affinity DataIC50:  8.80nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM531139(6-chloro-3-((2-((2,2-dimethyl-1-phenylbutyl)amino)...)
Affinity DataIC50:  9nMAssay Description:HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Macaca mulatta)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50463599(CHEMBL4245355)
Affinity DataIC50:  9.5nMAssay Description:Inhibition of monkey CCR6 expressed in CHO cells assessed as decrease in CCL20-induced reduction of forskolin-stimulated cAMP accumulation preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM291177(US9580412, Example 6 | US9580412, Example 7 | meth...)
Affinity DataIC50:  9.70nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM236788(US9388149, 19 | US9580412, Example 19)
Affinity DataIC50:  11nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM50463603(CHEMBL4239904)
Affinity DataIC50:  12nMAssay Description:Inhibition of human CCR6 expressed in CHO cells assessed as decrease in CCL20-induced reduction of forskolin-stimulated cAMP accumulation preincubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM531128((R)-6-chloro-3-((2-((5,5-dimethyl-4,5,6,7-tetrahyd...)
Affinity DataIC50:  12nMAssay Description:HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM50463578(CHEMBL4250007)
Affinity DataIC50:  13nMAssay Description:Inhibition of human CCR6 expressed in CHO cells assessed as decrease in CCL20-induced reduction of forskolin-stimulated cAMP accumulation preincubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM531113(6-chloro-3-((3,4-dioxo-2-((4,5,6,7-tetrahydrobenzo...)
Affinity DataIC50:  14nMAssay Description:HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Macaca mulatta)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50463578(CHEMBL4250007)
Affinity DataIC50:  16nMAssay Description:Inhibition of monkey CCR6 expressed in CHO cells assessed as decrease in CCL20-induced reduction of forskolin-stimulated cAMP accumulation preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM50463583(CHEMBL4242040)
Affinity DataIC50:  17nMAssay Description:Inhibition of human CCR6 expressed in CHO cells assessed as decrease in CCL20-induced reduction of forskolin-stimulated cAMP accumulation preincubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM531147(6-chloro-3-((2-((6,6-dimethyl-4,5,6,7-tetrahydrobe...)
Affinity DataIC50:  17nMAssay Description:HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM531124(3-((2-((5,5-dimethyl-4,5,6,7-tetrahydrobenzofuran-...)
Affinity DataIC50:  17nMAssay Description:HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM50463599(CHEMBL4245355)
Affinity DataIC50:  17nMAssay Description:Inhibition of human CCR6 expressed in CHO cells assessed as decrease in CCL20-induced reduction of forskolin-stimulated cAMP accumulation preincubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM531148(3-((2-((6,6-dimethyl-4,5,6,7-tetrahydrobenzofuran-...)
Affinity DataIC50:  18nMAssay Description:HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM531188(3-((4-chloro-2-hydroxy-3-((4-methylpiperazin-1-yl)...)
Affinity DataIC50:  19nMAssay Description:HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM531133(6-chloro-3-((2-((2,2-dimethyl-1-(5-methylfuran-2-y...)
Affinity DataIC50:  19nMAssay Description:HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Macaca mulatta)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50463583(CHEMBL4242040)
Affinity DataIC50:  21nMAssay Description:Inhibition of monkey CCR6 expressed in CHO cells assessed as decrease in CCL20-induced reduction of forskolin-stimulated cAMP accumulation preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM531121(6-chloro-3-((2-((2,2-dimethyl-1-(m-tolyl)propyl)am...)
Affinity DataIC50:  24nMAssay Description:HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM50463604(CHEMBL4251268)
Affinity DataIC50:  24nMAssay Description:Inhibition of human CCR6 expressed in CHO cells assessed as decrease in CCL20-induced reduction of forskolin-stimulated cAMP accumulation preincubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM531144(3-((5,5-dimethyl-4,5,6,7-tetrahydrobenzofuran-4-yl...)
Affinity DataIC50:  25nMAssay Description:HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM531160(6-chloro-3-((2-((2,2-dimethylcyclohexyl)amino)-3,4...)
Affinity DataIC50:  25nMAssay Description:HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM531083(6-chloro-3-((2-((2,2-dimethyl-1,2,3,4-tetrahydrona...)
Affinity DataIC50:  26nMAssay Description:HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM531132(6-chloro-3-((2-((1-(furan-2-yl)-2,2-dimethylpropyl...)
Affinity DataIC50:  26nMAssay Description:HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM50463579(CHEMBL4249063)
Affinity DataIC50:  27nMAssay Description:Inhibition of human CCR6 expressed in CHO cells assessed as decrease in CCL20-induced reduction of forskolin-stimulated cAMP accumulation preincubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM531181(6-chloro-3-((2-((cyclopentyl(phenyl)methyl)amino)-...)
Affinity DataIC50:  27nMAssay Description:HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM531182(6-chloro-2-hydroxy-3-((2-((1-(2-methoxyethyl)cyclo...)
Affinity DataIC50:  28nMAssay Description:HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM531127(6-chloro-3-((2-((5,5-dimethyl-4,5,6,7-tetrahydrobe...)
Affinity DataIC50:  28nMAssay Description:HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM531193(6-chloro-3-((2-((1-ethylcyclopentyl)amino)-3,4-dio...)
Affinity DataIC50:  30nMAssay Description:HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM50463591(CHEMBL4248604)
Affinity DataIC50: <30nMAssay Description:Inhibition of human CCR6 expressed in CHO cells assessed as decrease in human CCL20-dependent cell migration incubated for 4 hrs by Diff-Quik stainin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM531122(6-chloro-3-((3,4-dioxo-2-((2,3,3-trimethylbutan-2-...)
Affinity DataIC50:  30nMAssay Description:HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM531120(6-chloro-2-hydroxy-3-((2-((1-(3-methoxyphenyl)-2,2...)
Affinity DataIC50:  30nMAssay Description:HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM50463601(CHEMBL4239428)
Affinity DataIC50:  31nMAssay Description:Inhibition of human CCR6 expressed in CHO cells assessed as decrease in CCL20-induced reduction of forskolin-stimulated cAMP accumulation preincubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM531145(3-((4-chloro-2-hydroxy-3-((4-methylpiperazin-1-yl)...)
Affinity DataIC50:  31nMAssay Description:HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM531208(6-chloro-2-hydroxy-N,N-dimethyl-3-((2-((1-methylcy...)
Affinity DataIC50:  35nMAssay Description:HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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