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Found 961 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 6'
TargetCarbonic anhydrase 6(Bos taurus)TBA
LigandPNGBDBM50212308(CHEMBL130950)
Affinity DataIC50:  5nMAssay Description:In vitro concentration that causes 50% inhibition of carbonic anhydrase carbonate hydro-lyase (EC.4.2.1.1) isolated from bovine erythrocyteMore data for this Ligand-Target Pair
In DepthDetails
TargetCarbonic anhydrase 6(Bos taurus)TBA
LigandPNGBDBM50212306(CHEMBL129880)
Affinity DataIC50:  7nMAssay Description:In vitro concentration that causes 50% inhibition of carbonic anhydrase carbonate hydro-lyase (EC.4.2.1.1) isolated from bovine erythrocyteMore data for this Ligand-Target Pair
In DepthDetails
TargetCarbonic anhydrase 6(Bos taurus)TBA
LigandPNGBDBM50212310(CHEMBL335243)
Affinity DataIC50:  8nMAssay Description:In vitro concentration that causes 50% inhibition of carbonic anhydrase carbonate hydro-lyase (EC.4.2.1.1) isolated from bovine erythrocyteMore data for this Ligand-Target Pair
In DepthDetails
TargetCarbonic anhydrase 6(Bos taurus)TBA
LigandPNGBDBM50212307(CHEMBL336554)
Affinity DataIC50:  9nMAssay Description:In vitro concentration that causes 50% inhibition of carbonic anhydrase carbonate hydro-lyase (EC.4.2.1.1) isolated from bovine erythrocyteMore data for this Ligand-Target Pair
In DepthDetails
TargetCarbonic anhydrase 6(Bos taurus)TBA
LigandPNGBDBM50080659(2-Amino-N-(5-sulfamoyl-[1,3,4]thiadiazol-2-yl)-ace...)
Affinity DataIC50:  10nMAssay Description:In vitro concentration that causes 50% inhibition of carbonic anhydrase carbonate hydro-lyase (EC.4.2.1.1) isolated from bovine erythrocyteMore data for this Ligand-Target Pair
In DepthDetails
TargetCarbonic anhydrase 6(Bos taurus)TBA
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataIC50:  16nMAssay Description:In vitro concentration that causes 50% inhibition of carbonic anhydrase carbonate hydro-lyase (EC.4.2.1.1) isolated from bovine erythrocyteMore data for this Ligand-Target Pair
In DepthDetails
TargetCarbonic anhydrase 6(Bos taurus)TBA
LigandPNGBDBM50004172(CHEMBL544763 | Sulfamic acid 2-(4-imidazol-1-yl-ph...)
Affinity DataIC50:  23nMAssay Description:Bovine erythrocyte carbonic anhydrase inhibitory activity of the compound.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Bos taurus)TBA
LigandPNGBDBM50212316(CHEMBL133619)
Affinity DataIC50:  30nMAssay Description:In vitro concentration that causes 50% inhibition of carbonic anhydrase carbonate hydro-lyase (EC.4.2.1.1) isolated from bovine erythrocyteMore data for this Ligand-Target Pair
In DepthDetails
TargetCarbonic anhydrase 6(Bos taurus)TBA
LigandPNGBDBM50230218(CHEMBL545555)
Affinity DataIC50:  42nMAssay Description:Bovine erythrocyte carbonic anhydrase inhibitory activity of the compound.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Bos taurus)TBA
LigandPNGBDBM50230217(CHEMBL555867)
Affinity DataIC50:  50nMAssay Description:Bovine erythrocyte carbonic anhydrase inhibitory activity of the compound.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Bos taurus)TBA
LigandPNGBDBM50230221(CHEMBL541599)
Affinity DataIC50:  69nMAssay Description:Bovine erythrocyte carbonic anhydrase inhibitory activity of the compound.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Bos taurus)TBA
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataIC50:  72nMAssay Description:Bovine erythrocyte carbonic anhydrase inhibitory activity of the compound.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Bos taurus)TBA
LigandPNGBDBM50230214(CHEMBL555738)
Affinity DataIC50:  77nMAssay Description:Bovine erythrocyte carbonic anhydrase inhibitory activity of the compound.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Bos taurus)TBA
LigandPNGBDBM50230219(CHEMBL545088)
Affinity DataIC50:  94nMAssay Description:Bovine erythrocyte carbonic anhydrase inhibitory activity of the compound.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Bos taurus)TBA
LigandPNGBDBM50230216(CHEMBL553542)
Affinity DataIC50:  120nMAssay Description:Bovine erythrocyte carbonic anhydrase inhibitory activity of the compound.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Bos taurus)TBA
LigandPNGBDBM50230220(CHEMBL555771)
Affinity DataIC50:  210nMAssay Description:Bovine erythrocyte carbonic anhydrase inhibitory activity of the compound.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Bos taurus)TBA
LigandPNGBDBM50230215(CHEMBL543683)
Affinity DataIC50:  250nMAssay Description:Bovine erythrocyte carbonic anhydrase inhibitory activity of the compound.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataIC50:  340nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Bos taurus)TBA
LigandPNGBDBM50212309(CHEMBL91302)
Affinity DataIC50:  440nMAssay Description:In vitro concentration that causes 50% inhibition of carbonic anhydrase carbonate hydro-lyase (EC.4.2.1.1) isolated from bovine erythrocyteMore data for this Ligand-Target Pair
In DepthDetails
TargetCarbonic anhydrase 6(Bos taurus)TBA
LigandPNGBDBM50212309(CHEMBL91302)
Affinity DataIC50:  440nMAssay Description:In vitro concentration that causes 50% inhibition of carbonic anhydrase carbonate hydro-lyase (EC.4.2.1.1) isolated from bovine erythrocyteMore data for this Ligand-Target Pair
In DepthDetails
TargetCarbonic anhydrase 6(Bos taurus)TBA
LigandPNGBDBM50212305(CHEMBL129895)
Affinity DataIC50:  550nMAssay Description:In vitro concentration that causes 50% inhibition of carbonic anhydrase carbonate hydro-lyase (EC.4.2.1.1) isolated from bovine erythrocyteMore data for this Ligand-Target Pair
In DepthDetails
TargetCarbonic anhydrase 6(Bos taurus)TBA
LigandPNGBDBM50212305(CHEMBL129895)
Affinity DataIC50:  570nMAssay Description:In vitro concentration that causes 50% inhibition of carbonic anhydrase carbonate hydro-lyase (EC.4.2.1.1) isolated from bovine erythrocyteMore data for this Ligand-Target Pair
In DepthDetails
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM237305(4-Methyl-N-(4-nitrophenyl) benzenesulfonamide (11))
Affinity DataIC50:  1.11E+3nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM10857(4-aminobenzene-1-sulfonamide | CHEMBL21 | Sulfanil...)
Affinity DataIC50:  1.21E+3nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM237304(N-(4-cyanophenyl)-4-methylbenzenesulfonamide (10))
Affinity DataIC50:  1.23E+3nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM237302(4-Methyl-N-(2-nitrophenyl) benzenesulfonamide (7))
Affinity DataIC50:  4.71E+3nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM237301(N-(2-cyanophenyl)-4-methylbenzenesulfonamide (6))
Affinity DataIC50:  8.43E+3nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM50166571(2-sulfanilamidopyrimidine | 2-sulfanilylaminopyrim...)
Affinity DataIC50:  1.16E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM50428400(CA inhibitor, 2 | CHEMBL182659 | [(4-Methylphenyl)...)
Affinity DataIC50:  1.34E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM39340(4-Amino-N-(pyrimidin-2-yl) benzenesulfonamide (Sul...)
Affinity DataIC50:  1.55E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM10859(4-methylbenzene-1-sulfonamide | CHEMBL574 | aromat...)
Affinity DataIC50:  1.90E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM237281(Carbonic anhydrase inhibitors (CAIs), 1)
Affinity DataIC50:  2.43E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM237303(N-(4-ethylphenyl)-4-methylbenzenesulfonamide (9))
Affinity DataIC50:  2.65E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM237300(4-Methyl-N-o-tolyl-benzenesulfonamide (5))
Affinity DataIC50:  2.96E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM50044857(CA inhibitor, 4 | CHEMBL3311314)
Affinity DataIC50:  3.22E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM50296250((S,Z)-3-(2-hydroxy-5-(1-hydroxy-3-methylbutyl)-4-m...)
Affinity DataIC50:  3.57E+4nMAssay Description:Inhibition of human carbonic anhydrase 6 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM45795(4-methyl-N-(2-naphthalenyl)benzenesulfonamide | 4-...)
Affinity DataIC50:  4.24E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM26995(CHEMBL355001 | H2NSO2NH2 | sulfamamide | sulfamide...)
Affinity DataKi:  0.0700nMAssay Description:Inhibition of human recombinant CA6 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM26994(CHEMBL68253 | H2NSO3H | sulfamic acid)
Affinity DataKi:  0.0900nMAssay Description:Inhibition of human recombinant CA6 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM50137675(4-(3,4,5-Trihydroxy-tetrahydro-pyran-2-ylamino)-be...)
Affinity DataKi:  0.560nM ΔG°:  -51.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM50137677(4-(3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyr...)
Affinity DataKi:  0.640nM ΔG°:  -51.6kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM11638(CHEMBL26 | Compound 7 | N-[(1-ethylpyrrolidin-2-yl...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of full length human recombinant CA VIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM11638(CHEMBL26 | Compound 7 | N-[(1-ethylpyrrolidin-2-yl...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of human recombinant CA6 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM11638(CHEMBL26 | Compound 7 | N-[(1-ethylpyrrolidin-2-yl...)
Affinity DataKi:  0.800nM ΔG°:  -51.1kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM10889(2-methoxy-N-[(1-methylpyrrolidin-2-yl)methyl]-5-su...)
Affinity DataKi:  0.800nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM26996(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)
Affinity DataKi:  0.820nMAssay Description:Inhibition of human recombinant CA6 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM10885((4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-...)
Affinity DataKi:  0.900nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM82123(Brinzolamide, BRZ)
Affinity DataKi:  0.900nM ΔG°:  -50.8kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM10885((4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-...)
Affinity DataKi:  0.900nMAssay Description:Inhibition of human recombinant CA6 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM10885((4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-...)
Affinity DataKi:  0.900nMAssay Description:Inhibition of full length human recombinant CA VIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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