TargetComplement C1s subcomponent(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human C1s esterolytic activity using benzyloxycarbonyl-Lys-thiobenzyl as substrateMore data for this Ligand-Target Pair
TargetComplement C1s subcomponent(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of human serum C1s using AGLME as substrate after 30 minsMore data for this Ligand-Target Pair
TargetComplement C1s subcomponent(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of human serum C1s-mediated lysis of rabbit Ab-sensitized sheep erythrocytes after 60 minsMore data for this Ligand-Target Pair
TargetComplement C1s subcomponent(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Compound was evaluated for inhibitory activity against C1s serine protease .More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
TargetComplement C1s subcomponent(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibitory activity of the compound against human Complement C1s subcomponent in erythrocyte hemolytic assayMore data for this Ligand-Target Pair
TargetComplement C1s subcomponent(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Dr. Scott L. Diamond, University of Pen...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Compound was evaluated in vitro for inhibitory activity against purified human C1r protease proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of human plasma C1r using Cbz-Gly-Arg-S-Bzl as substrate preincubated for 10 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of C1r serine proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:In vitro inhibition of purified human C1r protease.More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of human serum C1r using AAME as substrate after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
TargetComplement C1s subcomponent(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 850nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Dr. Scott L. Diamond, University of Pen...More data for this Ligand-Target Pair
TargetComplement C1s subcomponent(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 880nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Dr. Scott L. Diamond, University of Pen...More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
TargetComplement C1s subcomponent(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Dr. Scott L. Diamond, University of Pen...More data for this Ligand-Target Pair
TargetComplement C1s subcomponent(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of human plasma C1s using Cbz-Gly-Arg-S-Bzl as substrate preincubated for 10 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
TargetComplement C1s subcomponent(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 1.25E+3nMAssay Description:Compound was evaluated for inhibitory activity against C1s serine protease .More data for this Ligand-Target Pair
Affinity DataIC50: 1.37E+3nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro inhibition of purified human C1r protease.More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
TargetComplement C1s subcomponent(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 2.14E+3nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Dr. Scott L. Diamond, University of Pen...More data for this Ligand-Target Pair
TargetComplement C1s subcomponent(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 2.37E+3nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Dr. Scott L. Diamond, University of Pen...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:In vitro inhibition of purified human C1r protease.More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair