Compile Data Set for Download or QSAR
maximum 50k data
Found 745 Enz. Inhib. hit(s) with Target = 'Lysosomal Pro-X carboxypeptidase'
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235953(US9365539, 33)
Affinity DataIC50:  0.0350nMpH: 5.5Assay Description:The assay was run in a 384-well microliter plate at 37° C. with a total volume of 50 uL. Final assay concentrations were 0.13 nM human PrCP (CHO) or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50364407(CHEMBL1950444)
Affinity DataIC50:  0.0390nMAssay Description:Inhibition of mouse recombinant PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate for 30 mins by continuous fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235950(US9365539, 1)
Affinity DataIC50:  0.0510nMpH: 5.5Assay Description:The assay was run in a 384-well microliter plate at 37° C. with a total volume of 50 uL. Final assay concentrations were 0.13 nM human PrCP (CHO) or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50443348(CHEMBL3086040 | US8669252, 12)
Affinity DataIC50:  0.0790nMAssay Description:Inhibition of recombinant human PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50364689(CHEMBL1951478)
Affinity DataIC50:  0.110nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50443348(CHEMBL3086040 | US8669252, 12)
Affinity DataIC50:  0.160nMAssay Description:The potency of compounds of formula I against PrCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PrCP inhibit...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50364386(CHEMBL1950440)
Affinity DataIC50:  0.170nMAssay Description:Inhibition of human recombinant PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate for 30 mins by continuous fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50364676(CHEMBL1951465 | US8785634, 1)
Affinity DataIC50:  0.180nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50443351(CHEMBL3086037 | US8669252, 15)
Affinity DataIC50:  0.180nMAssay Description:Inhibition of recombinant human PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50443351(CHEMBL3086037 | US8669252, 15)
Affinity DataIC50:  0.180nMAssay Description:The potency of compounds of formula I against PrCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PrCP inhibit...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM119411(US8669252, 43)
Affinity DataIC50:  0.180nMAssay Description:The potency of compounds of formula I against PrCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PrCP inhibit...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50382913(CHEMBL2023210)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50383421(CHEMBL2031595)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50382899(CHEMBL2022787)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50382904(CHEMBL2022793)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50443348(CHEMBL3086040 | US8669252, 12)
Affinity DataIC50:  0.280nMAssay Description:Inhibition of recombinant mouse PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50382913(CHEMBL2023210)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50382906(CHEMBL2023202)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50382906(CHEMBL2023202)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50361786(CHEMBL1938522)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of recombinant human PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by continuous fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50364685(CHEMBL1951474)
Affinity DataIC50:  0.310nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235955(US9365539, 36)
Affinity DataIC50:  0.310nMpH: 5.5Assay Description:The assay was run in a 384-well microliter plate at 37° C. with a total volume of 50 uL. Final assay concentrations were 0.13 nM human PrCP (CHO) or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50364407(CHEMBL1950444)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of human recombinant PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate for 30 mins by continuous fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50364679(CHEMBL1951468 | US8785634, 2)
Affinity DataIC50:  0.380nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50364687(CHEMBL1951476 | US8785634, 8)
Affinity DataIC50:  0.390nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50383421(CHEMBL2031595)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50382906(CHEMBL2023202)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50382905(CHEMBL2022794)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50383427(CHEMBL2031588)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50382906(CHEMBL2023202)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50361774(CHEMBL1938510)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of recombinant mouse PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by continuous fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338033((S)-1-(2-(5,6-dichloro-1H-benzo[d]imidazol-2-yl)py...)
Affinity DataIC50:  0.410nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50364676(CHEMBL1951465 | US8785634, 1)
Affinity DataIC50:  0.440nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50364687(CHEMBL1951476 | US8785634, 8)
Affinity DataIC50:  0.490nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50364687(CHEMBL1951476 | US8785634, 8)
Affinity DataIC50:  0.490nMAssay Description:The potency of compounds of formula I against PrCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PrCP inhibit...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50382912(CHEMBL2023209 | US8569299, 4)
Affinity DataIC50:  0.5nMpH: 5.5 T: 2°CAssay Description:The potency of compounds against PRCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PRCP inhibitor test compo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50383425(CHEMBL2031590)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50382910(CHEMBL2023207)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50382912(CHEMBL2023209 | US8569299, 4)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235954(US9365539, 34)
Affinity DataIC50:  0.510nMpH: 5.5Assay Description:The assay was run in a 384-well microliter plate at 37° C. with a total volume of 50 uL. Final assay concentrations were 0.13 nM human PrCP (CHO) or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338029((S)-1-(2-(5,6-dichloro-1H-benzo[d]imidazol-2-yl)py...)
Affinity DataIC50:  0.530nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50361774(CHEMBL1938510)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of recombinant human PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by continuous fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50443352(CHEMBL3085780)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of recombinant human PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50443353(CHEMBL3086036 | US8669252, 14)
Affinity DataIC50:  0.660nMAssay Description:Inhibition of recombinant human PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50364676(CHEMBL1951465 | US8785634, 1)
Affinity DataIC50:  0.660nMAssay Description:The potency of compounds of formula I against PrCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PrCP inhibit...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM155349(US9006268, 21)
Affinity DataIC50:  0.700nMpH: 5.5Assay Description:The assay was run in a 384-well microtiter plate at 37° C. with a total volume of 50 uL. Final assay concentrations were 0.13 nM human PrCP (CHO) or...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50001308(CHEMBL3237393)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of recombinant mouse PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate after 30 mins by continuous fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50382898(CHEMBL2022786)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50364669(CHEMBL1951458)
Affinity DataIC50:  0.710nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50364685(CHEMBL1951474)
Affinity DataIC50:  0.730nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 745 total ) | Next | Last >>
Jump to: