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Found 1480 Enz. Inhib. hit(s) with Target = 'Neuropeptide Y receptor type 2'
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50208988(HUMAN NEUROPEPTIDE Y)
Affinity DataIC50:  0.0280nMAssay Description:Displacement of [125I]peptide YY from Y2 receptor in human KAN-TS cells measured after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(RAT)
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50091672(CHEMBL412704 | N-alpha-Ac-[CH2-NH35-36]PYY(22-36)-...)
Affinity DataIC50:  0.0500nMAssay Description:Antisecretory potency, affinity for intestinal PYY of rat jejunum by using short circuit current (SCC) method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50091652(CHEMBL269503 | PYY | PYY, rat | Peptide YY(PYY)(YP...)
Affinity DataIC50:  0.0700nMAssay Description:Affinity against Neuropeptide Y receptor Y2 in SK-N-BE2 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50015490(CHEMBL438945 | H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...)
Affinity DataIC50:  0.0900nMAssay Description:Binding affinity to human neuropeptide Y2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(RAT)
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50091652(CHEMBL269503 | PYY | PYY, rat | Peptide YY(PYY)(YP...)
Affinity DataIC50:  0.140nMAssay Description:Antisecretory potency, affinity for intestinal PYY of rat jejunum by using short circuit current (SCC) method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50451011(CHEMBL4216889)
Affinity DataIC50:  0.160nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount based methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50460001(CHEMBL4226347)
Affinity DataIC50:  0.190nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount micro scintillation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50460003(CHEMBL4224835)
Affinity DataIC50:  0.190nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount micro scintillation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50015490(CHEMBL438945 | H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...)
Affinity DataIC50:  0.190nMAssay Description:Binding affinity to human neuropeptide Y receptor type 2 by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50435127(CHEMBL2392022)
Affinity DataIC50:  0.210nMAssay Description:Displacement of [125I]Peptide YY from neuropeptide Y receptor type 2 in human KAN-TS cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50451012(CHEMBL4208191)
Affinity DataIC50:  0.270nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount based methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM392076(US10301272, Example 7/9)
Affinity DataIC50:  0.280nMAssay Description:Displacement of [125I]peptide YY from human Y2 receptor after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(RAT)
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50091663(CHEMBL214707 | N-alpha-Ac-[Trp30,CH2-NH-35-36]PYY(...)
Affinity DataIC50:  0.280nMAssay Description:Antisecretory potency, affinity for intestinal PYY of rat jejunum by using short circuit current (SCC) method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50451003(CHEMBL4207076)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount based methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(RAT)
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50091684(CHEMBL412257 | N-alpha-Ac-[Nle24,28,Trp30,Nva31,CH...)
Affinity DataIC50:  0.310nMAssay Description:Antisecretory potency, affinity for intestinal PYY of rat jejunum by using short circuit current (SCC) method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50450993(CHEMBL4210786)
Affinity DataIC50:  0.310nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount based methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50005530(CHEMBL267633 | D-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-G...)
Affinity DataIC50:  0.320nMAssay Description:Affinity against Neuropeptide Y receptor Y2 in SK-N-BE2 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(RAT)
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50091669(CHEMBL438923 | N-alpha-Ac-[CH2-NH28-29]PYY(22-36)-...)
Affinity DataIC50:  0.360nMAssay Description:Antisecretory potency, affinity for intestinal PYY of rat jejunum by using short circuit current (SCC) method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50091679(CHEMBL441007 | bis(24/24'){N-alpha-Ac-[Cys24]PYY(2...)
Affinity DataIC50:  0.390nMAssay Description:Affinity against Neuropeptide Y receptor Y2 in SK-N-BE2 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50450996(CHEMBL4212927)
Affinity DataIC50:  0.400nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount based methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50451008(CHEMBL4211953)
Affinity DataIC50:  0.410nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount based methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50451027(CHEMBL4211310)
Affinity DataIC50:  0.440nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount based methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50451025(CHEMBL4204797)
Affinity DataIC50:  0.450nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount based methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(RAT)
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50034128(CHEMBL441396 | Neuropeptide Y(NPY) | Tyr-Pro-Ser-L...)
Affinity DataIC50:  0.450nMAssay Description:50% displacement of specifically bound [3H]-NPY2 from rat brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50451030(CHEMBL4216864)
Affinity DataIC50:  0.460nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount based methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50269185(CHEMBL4069788)
Affinity DataIC50:  0.490nMAssay Description:Displacement of [125I]peptide YY from human Y2 receptor expressed in CHO cell membranes after 60 mins by TopCount scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50015490(CHEMBL438945 | H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...)
Affinity DataIC50:  0.5nMAssay Description:Compound was evaluated for its inhibitory activity against Y2 receptor of rabbit kidney membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50450998(CHEMBL4207590)
Affinity DataIC50:  0.510nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount based methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50269166(CHEMBL4063306)
Affinity DataIC50:  0.550nMAssay Description:Displacement of [125I]peptide YY from human Y2 receptor expressed in CHO cell membranes after 60 mins by TopCount scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(RAT)
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50091651(CHEMBL411200 | N-alpha-Ac-[Nle24,28,Trp30,Nva31]PY...)
Affinity DataIC50:  0.560nMAssay Description:Antisecretory potency, affinity for intestinal PYY of rat jejunum by using short circuit current (SCC) method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50450997(CHEMBL4202723)
Affinity DataIC50:  0.570nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount based methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50197025(CHEMBL439904 | PYY(3-36))
Affinity DataIC50:  0.570nMAssay Description:Displacement of [125I]peptide YY from human Y2 receptor expressed in CHO cell membranes after 60 mins by TopCount scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50197025(CHEMBL439904 | PYY(3-36))
Affinity DataIC50:  0.570nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount based methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50254346(CHEMBL4069932)
Affinity DataIC50:  0.570nMAssay Description:Displacement of [125I]-PYY from human Y2R expressed in CHO cell membranes after 60 mins by liquid scintillation methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50450994(CHEMBL4206938)
Affinity DataIC50:  0.580nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount based methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(RAT)
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50091653(CHEMBL266021 | N-alpha-Ac-[Nle24,28,30,Nva31]PYY(2...)
Affinity DataIC50:  0.590nMAssay Description:Antisecretory potency, affinity for intestinal PYY of rat jejunum by using short circuit current (SCC) method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(RAT)
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50091674(CHEMBL412698 | N-alpha-Ac-[D-Trp30]PYY(22-36)-NH2(...)
Affinity DataIC50:  0.600nMAssay Description:Antisecretory potency, affinity for intestinal PYY of rat jejunum by using short circuit current (SCC) method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(RAT)
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50091661(CHEMBL410938 | N-alpha-Ac-[Trp28]PYY(22-36)-NH2(N-...)
Affinity DataIC50:  0.600nMAssay Description:Tested for the affinity for intestinal PYY from rat jejunum by using short circuit current (SCC) method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50269168(CHEMBL4069205)
Affinity DataIC50:  0.600nMAssay Description:Displacement of [125I]peptide YY from human Y2 receptor expressed in CHO cell membranes after 60 mins by TopCount scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(RAT)
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50091679(CHEMBL441007 | bis(24/24'){N-alpha-Ac-[Cys24]PYY(2...)
Affinity DataIC50:  0.630nMAssay Description:Antisecretory potency, affinity for intestinal PYY of rat jejunum by using short circuit current (SCC) method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50451026(CHEMBL4208856)
Affinity DataIC50:  0.670nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount based methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50269163(CHEMBL4094429)
Affinity DataIC50:  0.700nMAssay Description:Displacement of [125I]peptide YY from human Y2 receptor expressed in CHO cell membranes after 60 mins by TopCount scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50254345(CHEMBL4075597)
Affinity DataIC50:  0.700nMAssay Description:Displacement of [125I]-PYY from human Y2R expressed in CHO cell membranes after 60 mins by liquid scintillation methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50450995(CHEMBL4208023)
Affinity DataIC50:  0.780nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount based methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(RAT)
University Of Cincinnati Medical Center

Curated by ChEMBL
LigandPNGBDBM50091668(AcPYY(22-36) | CHEMBL269267 | N-alpha-Ac-PYY(22-36...)
Affinity DataIC50:  0.910nMAssay Description:Antisecretory potency, affinity for intestinal PYY of rat jejunum by using short circuit current (SCC) method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50451029(CHEMBL4206417)
Affinity DataIC50:  0.910nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount based methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50269184(CHEMBL4064778)
Affinity DataIC50:  0.920nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount based methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50269184(CHEMBL4064778)
Affinity DataIC50:  0.920nMAssay Description:Displacement of [125I]peptide YY from human Y2 receptor expressed in CHO cell membranes after 60 mins by TopCount scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50269167(CHEMBL4085697)
Affinity DataIC50:  0.940nMAssay Description:Displacement of [125I]peptide YY from human Y2 receptor expressed in CHO cell membranes after 60 mins by TopCount scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50269169(CHEMBL4090786)
Affinity DataIC50:  0.970nMAssay Description:Displacement of [125I]peptide YY from human Y2 receptor expressed in CHO cell membranes after 60 mins by TopCount scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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