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Found 304 Enz. Inhib. hit(s) with Target = 'Penicillin-binding protein'
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50422689(640/359 | CEFUROXIME)
Affinity DataIC50:  0.0940nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3009 PBP2XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50422689(640/359 | CEFUROXIME)
Affinity DataIC50:  1.18nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3413 PBP2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50422689(640/359 | CEFUROXIME)
Affinity DataIC50:  2.36nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3413 PBP1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50422689(640/359 | CEFUROXIME)
Affinity DataIC50:  4.71nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 1076 PBP2XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50422689(640/359 | CEFUROXIME)
Affinity DataIC50:  4.71nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3665 PBP1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50022787((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...)
Affinity DataIC50:  5.98nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 2527 PBP1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50422689(640/359 | CEFUROXIME)
Affinity DataIC50:  7.07nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 2527 PBP2XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50422689(640/359 | CEFUROXIME)
Affinity DataIC50:  9.43nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3413 PBP2XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50422689(640/359 | CEFUROXIME)
Affinity DataIC50:  9.43nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 1076 PBP1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50422689(640/359 | CEFUROXIME)
Affinity DataIC50:  9.43nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 24 PBP1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50350464(AMOXICILLINE | Amoxi-Inject | Amoxi-Tabs | Amoxici...)
Affinity DataIC50:  10.9nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 2527 PBP2XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50350464(AMOXICILLINE | Amoxi-Inject | Amoxi-Tabs | Amoxici...)
Affinity DataIC50:  10.9nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 24 PBP1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50483324(CHEBI:51257 | Faropenem)
Affinity DataIC50:  14nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3243 PBP1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50422689(640/359 | CEFUROXIME)
Affinity DataIC50:  14.1nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3243 PBP1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50422689(640/359 | CEFUROXIME)
Affinity DataIC50:  14.1nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 1077 PBP2XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50422689(640/359 | CEFUROXIME)
Affinity DataIC50:  14.1nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 2527 PBP1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50422689(640/359 | CEFUROXIME)
Affinity DataIC50:  18.9nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3676 PBP1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50022787((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...)
Affinity DataIC50:  20.9nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3243 PBP2XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50022787((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...)
Affinity DataIC50:  20.9nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3009 PBP2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50350464(AMOXICILLINE | Amoxi-Inject | Amoxi-Tabs | Amoxici...)
Affinity DataIC50:  21.9nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3009 PBP2XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50422689(640/359 | CEFUROXIME)
Affinity DataIC50:  23.6nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3009 PBP1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50022787((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...)
Affinity DataIC50:  23.9nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 1077 PBP2XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50022787((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...)
Affinity DataIC50:  23.9nMAssay Description:Inhibition of Bocillin FL binding to Streptococcus pneumoniae isolate 8865 PBP2bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50022787((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...)
Affinity DataIC50:  23.9nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3243 PBP1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50022787((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...)
Affinity DataIC50:  23.9nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 24 PBP1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50483324(CHEBI:51257 | Faropenem)
Affinity DataIC50:  24.5nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3009 PBP2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50022787((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...)
Affinity DataIC50:  26.9nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3009 PBP1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50022787((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...)
Affinity DataIC50:  26.9nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 2527 PBP2XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50022787((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...)
Affinity DataIC50:  26.9nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 1077 PBP1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50483324(CHEBI:51257 | Faropenem)
Affinity DataIC50:  28nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 1077 PBP2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50022787((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...)
Affinity DataIC50:  29.9nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 1076 PBP2XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 1A(Pseudomonas aeruginosa PAO1)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012177(CHEMBL3265226)
Affinity DataIC50:  30nMAssay Description:Displacement of fluorescent Bocillin FL from N-terminal His tagged Pseudomonas aeruginosa PAO1 PBP1a (residues 36 to 822) expressed in Escherichia co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50483324(CHEBI:51257 | Faropenem)
Affinity DataIC50:  31.5nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 24 PBP1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50022787((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...)
Affinity DataIC50:  32.9nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3009 PBP2XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50422689(640/359 | CEFUROXIME)
Affinity DataIC50:  33nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3243 PBP2XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50422689(640/359 | CEFUROXIME)
Affinity DataIC50:  33nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3665 PBP2XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50483324(CHEBI:51257 | Faropenem)
Affinity DataIC50:  35nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3009 PBP1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50483324(CHEBI:51257 | Faropenem)
Affinity DataIC50:  35nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 2527 PBP2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50022787((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...)
Affinity DataIC50:  35.9nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3676 PBP1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50483324(CHEBI:51257 | Faropenem)
Affinity DataIC50:  45.6nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 1076 PBP2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50483324(CHEBI:51257 | Faropenem)
Affinity DataIC50:  45.6nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3243 PBP2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 1A(Pseudomonas aeruginosa PAO1)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012179(CHEMBL3265221)
Affinity DataIC50:  46nMAssay Description:Displacement of fluorescent Bocillin FL from N-terminal His tagged Pseudomonas aeruginosa PAO1 PBP1a (residues 36 to 822) expressed in Escherichia co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 1A(Pseudomonas aeruginosa PAO1)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012181(CHEMBL3265225)
Affinity DataIC50:  46nMAssay Description:Displacement of fluorescent Bocillin FL from N-terminal His tagged Pseudomonas aeruginosa PAO1 PBP1a (residues 36 to 822) expressed in Escherichia co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 1A(Pseudomonas aeruginosa PAO1)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012180(CHEMBL3265224)
Affinity DataIC50:  46nMAssay Description:Displacement of fluorescent Bocillin FL from N-terminal His tagged Pseudomonas aeruginosa PAO1 PBP1a (residues 36 to 822) expressed in Escherichia co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 1A(Pseudomonas aeruginosa PAO1)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012178(CHEMBL3265220)
Affinity DataIC50:  46nMAssay Description:Displacement of fluorescent Bocillin FL from N-terminal His tagged Pseudomonas aeruginosa PAO1 PBP1a (residues 36 to 822) expressed in Escherichia co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50350464(AMOXICILLINE | Amoxi-Inject | Amoxi-Tabs | Amoxici...)
Affinity DataIC50:  46.5nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 1077 PBP1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50422689(640/359 | CEFUROXIME)
Affinity DataIC50:  47.1nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3676 PBP2XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50022787((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...)
Affinity DataIC50:  47.8nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 1076 PBP1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50350464(AMOXICILLINE | Amoxi-Inject | Amoxi-Tabs | Amoxici...)
Affinity DataIC50:  49.3nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3243 PBP2XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 2(Staphylococcus aureus)
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50482776(CHEBI:70718 | Ceftaroline Fosamil | PPI-0903 | TAK...)
Affinity DataIC50:  49.7nMAssay Description:Binding affinity to methicillin-susceptible Staphylococcus aureus PBP 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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