Compile Data Set for Download or QSAR
maximum 50k data
Found 32 Enz. Inhib. hit(s) with Target = 'Peptidyl-glycine alpha-amidating monooxygenase'
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50401749(CHEMBL2207130)
Affinity DataIC50:  2.00E+3nMAssay Description:Competitive inhibition of PAM in human DMS53 cells using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50401751(CHEMBL2207128)
Affinity DataIC50:  3.00E+3nMAssay Description:Competitive inhibition of PAM in human DMS53 cells using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50401752(CHEMBL2207127)
Affinity DataIC50:  5.00E+3nMAssay Description:Competitive inhibition of PAM in human DMS53 cells using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50401750(CHEMBL2207129)
Affinity DataIC50:  6.00E+3nMAssay Description:Competitive inhibition of PAM in human DMS53 cells using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50401751(CHEMBL2207128)
Affinity DataIC50:  9.00E+3nMAssay Description:Competitive inhibition of secreted PAM in human DMS53 cell culture medium using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50401752(CHEMBL2207127)
Affinity DataIC50:  1.10E+4nMAssay Description:Competitive inhibition of secreted PAM in human DMS53 cell culture medium using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50401756(CHEMBL2207143)
Affinity DataIC50:  1.20E+4nMAssay Description:Competitive inhibition of PAM in human DMS53 cells using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50401749(CHEMBL2207130)
Affinity DataIC50:  2.30E+4nMAssay Description:Competitive inhibition of secreted PAM in human DMS53 cell culture medium using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50401750(CHEMBL2207129)
Affinity DataIC50:  3.80E+4nMAssay Description:Competitive inhibition of secreted PAM in human DMS53 cell culture medium using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50401756(CHEMBL2207143)
Affinity DataIC50:  7.10E+4nMAssay Description:Competitive inhibition of secreted PAM in human DMS53 cell culture medium using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50401757(CHEMBL2207142)
Affinity DataIC50:  7.60E+4nMAssay Description:Competitive inhibition of PAM in human DMS53 cells using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50401758(CHEMBL2207141)
Affinity DataIC50:  1.20E+5nMAssay Description:Competitive inhibition of PAM in human DMS53 cells using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50401746(CHEMBL2207133)
Affinity DataIC50:  1.60E+5nMAssay Description:Competitive inhibition of secreted PAM in human DMS53 cell culture medium using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50401757(CHEMBL2207142)
Affinity DataIC50:  1.80E+5nMAssay Description:Competitive inhibition of secreted PAM in human DMS53 cell culture medium using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50401758(CHEMBL2207141)
Affinity DataIC50:  2.00E+5nMAssay Description:Competitive inhibition of secreted PAM in human DMS53 cell culture medium using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50401759(CHEMBL2207140)
Affinity DataIC50:  2.10E+5nMAssay Description:Competitive inhibition of PAM in human DMS53 cells using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50401754(CHEMBL2207145)
Affinity DataIC50:  2.90E+5nMAssay Description:Competitive inhibition of secreted PAM in human DMS53 cell culture medium using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50401747(CHEMBL2207132)
Affinity DataIC50:  3.50E+5nMAssay Description:Competitive inhibition of PAM in human DMS53 cells using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50401754(CHEMBL2207145)
Affinity DataIC50:  3.70E+5nMAssay Description:Competitive inhibition of PAM in human DMS53 cells using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50401747(CHEMBL2207132)
Affinity DataIC50:  3.70E+5nMAssay Description:Competitive inhibition of secreted PAM in human DMS53 cell culture medium using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50401755(CHEMBL2207144)
Affinity DataIC50:  5.00E+5nMAssay Description:Competitive inhibition of secreted PAM in human DMS53 cell culture medium using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50401746(CHEMBL2207133)
Affinity DataIC50:  5.60E+5nMAssay Description:Competitive inhibition of PAM in human DMS53 cells using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50401755(CHEMBL2207144)
Affinity DataIC50:  6.00E+5nMAssay Description:Competitive inhibition of PAM in human DMS53 cells using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50401753(CHEMBL2207146)
Affinity DataIC50:  9.80E+5nMAssay Description:Competitive inhibition of PAM in human DMS53 cells using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50401748(CHEMBL2207131)
Affinity DataIC50:  1.10E+6nMAssay Description:Competitive inhibition of PAM in human DMS53 cells using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM82195(Substrate analogue, 13)
Affinity DataIC50:  1.10E+6nMAssay Description:Competitive inhibition of secreted PAM in human DMS53 cell culture medium using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50401753(CHEMBL2207146)
Affinity DataIC50:  1.10E+6nMAssay Description:Competitive inhibition of secreted PAM in human DMS53 cell culture medium using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM82195(Substrate analogue, 13)
Affinity DataIC50:  1.10E+6nMAssay Description:Competitive inhibition of PAM in human DMS53 cells using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50401748(CHEMBL2207131)
Affinity DataIC50:  1.60E+6nMAssay Description:Competitive inhibition of secreted PAM in human DMS53 cell culture medium using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50401759(CHEMBL2207140)
Affinity DataIC50:  1.80E+6nMAssay Description:Competitive inhibition of secreted PAM in human DMS53 cell culture medium using as(R)-Tyr-(S)-Val-Gly as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50288771(((E)-Styrylsulfanyl)-acetic acid | CHEMBL127222)
Affinity DataKi:  0.100nMAssay Description:Kinetic constant for inhibition of peptidylglycine alpha hydroxylating monooxygenase (PHM) was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPeptidyl-glycine alpha-amidating monooxygenase(Homo sapiens (Human))
Australian National University

Curated by ChEMBL
LigandPNGBDBM50288770(CHEMBL335660 | Phenylethynylsulfanyl-acetic acid)
Affinity DataKi:  0.190nMAssay Description:Kinetic constant for inhibition of peptidylglycine alpha hydroxylating monooxygenase (PHM) was determinedMore data for this Ligand-Target Pair
In DepthDetails Article