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Found 65 Enz. Inhib. hit(s) with Target = 'Phosphatidylcholine:ceramide cholinephosphotransferase 1'
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545128(CHEMBL4641888)
Affinity DataIC50:  850nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50282224(CHEMBL4172856)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242188(6-(8'Z-pentadecenyl)-salicylicacid | 6-[8'(Z)-pent...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of SMS1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50182487(Malabaricone A)
Affinity DataIC50:  2.00E+3nMAssay Description:Noncompetitive inhibition of SMS1 (unknown origin) stably expressed in mouse ZS cells using 5 to 50 uM C6-NBD-ceramide as substrate preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50182491(CHEBI:69015 | Malabaricone C)
Affinity DataIC50:  2.00E+3nMAssay Description:Noncompetitive inhibition of SMS1 (unknown origin) stably expressed in mouse ZS cells using 5 to 50 uM C6-NBD-ceramide as substrate preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50182486(MALABARICONE B)
Affinity DataIC50:  2.00E+3nMAssay Description:Noncompetitive inhibition of SMS1 (unknown origin) stably expressed in mouse ZS cells using 5 to 50 uM C6-NBD-ceramide as substrate preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50117841(CHEMBL3613983)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545129(CHEMBL4645607)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50182491(CHEBI:69015 | Malabaricone C)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of SMS1 (unknown origin) stably expressed in mouse ZS cells using C6-NBD-ceramide as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545122(CHEMBL4646354)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50182486(MALABARICONE B)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of SMS1 (unknown origin) stably expressed in mouse ZS cells using C6-NBD-ceramide as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50182487(Malabaricone A)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of SMS1 (unknown origin) stably expressed in mouse ZS cells using C6-NBD-ceramide as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50117832(CHEMBL3613975)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50117840(CHEMBL3612087)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50182488(CHEMBL3819036)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of SMS1 (unknown origin) stably expressed in mouse ZS cells using C6-NBD-ceramide as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50117845(CHEMBL3613987)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50117842(CHEMBL3613984)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50117853(CHEMBL3613995)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545126(CHEMBL4646540)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50117846(CHEMBL3613988)
Affinity DataIC50:  1.05E+4nMAssay Description:Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Mus musculus)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50182491(CHEBI:69015 | Malabaricone C)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of SMS1 in MEF cells using C6-NBD-ceramide as substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr by HP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545121(CHEMBL4638097)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50282208(CHEMBL4177314)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of full length C-terminal FLAG tagged human SMS1 expressed in HEK293 cell membranes using DMPC-d72 and C17-ceramide as substrate preincuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545120(CHEMBL4634697)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50117848(CHEMBL3613990)
Affinity DataIC50:  1.42E+4nMAssay Description:Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50117844(CHEMBL3613986)
Affinity DataIC50:  1.47E+4nMAssay Description:Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545124(CHEMBL4639746)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545114(CHEMBL4644982)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50117843(CHEMBL3613985)
Affinity DataIC50:  1.56E+4nMAssay Description:Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545127(CHEMBL4644293)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545123(CHEMBL4638337)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545116(CHEMBL4649105)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50117839(CHEMBL3613982)
Affinity DataIC50:  2.31E+4nMAssay Description:Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545119(CHEMBL4634669)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50458937(CHEMBL4217275)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of human SMS1 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50458939(CHEMBL4202436)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of human SMS1 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50458926(CHEMBL4211357)
Affinity DataIC50:  4.80E+4nMAssay Description:Inhibition of human SMS1 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50117838(CHEMBL3613981)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50117847(CHEMBL3613989)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50117836(CHEMBL3613979)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50458921(CHEMBL4204352)
Affinity DataIC50:  5.60E+4nMAssay Description:Inhibition of human SMS1 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50458919(CHEMBL4207944)
Affinity DataIC50:  6.70E+4nMAssay Description:Inhibition of human SMS1 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50458938(CHEMBL4203399)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of human SMS1 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50458932(CHEMBL4217676)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of human SMS1 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50458942(CHEMBL4202973)
Affinity DataIC50:  7.90E+4nMAssay Description:Inhibition of human SMS1 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50458927(CHEMBL4214637)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of human SMS1 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50282209(CHEMBL1161894)
Affinity DataIC50:  8.60E+4nMAssay Description:Compound was evaluated for its inhibitory activity against human Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50282210(CHEMBL4162182)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human SMS1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545117(CHEMBL4647686)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50117833(CHEMBL3613976)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of sphingomyelin synthase-1 (unknown origin) expressed in HeLa cells using C6-NBD-Cer and DMPC as substrate after 2 hrs by fluorescent HPL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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