Compile Data Set for Download or QSAR
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Found 635 Enz. Inhib. hit(s) with Target = 'Adenylate cyclase'
TargetAdenylate cyclase type 10(Homo sapiens (Human))
Tri-Institutional Institutional Therapeutics Discovery Institute

Curated by ChEMBL
LigandPNGBDBM50607683(CHEMBL5219579)
Affinity DataKd:  1.10nMAssay Description:Binding affinity to human recombinant His-tagged ADCY10 assessed as dissociation constant and measured for 600 sec by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenylate cyclase type 10(Homo sapiens (Human))
Tri-Institutional Institutional Therapeutics Discovery Institute

Curated by ChEMBL
LigandPNGBDBM50607686(CHEMBL5219830)
Affinity DataKd:  1.40nMAssay Description:Binding affinity to human recombinant His-tagged ADCY10 assessed as dissociation constant and measured for 600 sec by SPR analysisMore data for this Ligand-Target Pair
TargetAdenylate cyclase type 10(Homo sapiens (Human))
Tri-Institutional Institutional Therapeutics Discovery Institute

Curated by ChEMBL
LigandPNGBDBM50607682(CHEMBL5220685)
Affinity DataKd:  1.70nMAssay Description:Binding affinity to human recombinant His-tagged ADCY10 assessed as dissociation constant and measured for 600 sec by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenylate cyclase type 10(Homo sapiens (Human))
Tri-Institutional Institutional Therapeutics Discovery Institute

Curated by ChEMBL
LigandPNGBDBM50607679(CHEMBL5218615)
Affinity DataKd:  2.10nMAssay Description:Binding affinity to human recombinant His-tagged ADCY10 assessed as dissociation constant and measured for 600 sec by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenylate cyclase type 10(Homo sapiens (Human))
Tri-Institutional Institutional Therapeutics Discovery Institute

Curated by ChEMBL
LigandPNGBDBM50607685(CHEMBL5220647)
Affinity DataKd:  2.30nMAssay Description:Binding affinity to human recombinant His-tagged ADCY10 assessed as dissociation constant and measured for 600 sec by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenylate cyclase type 10(Homo sapiens (Human))
Tri-Institutional Institutional Therapeutics Discovery Institute

Curated by ChEMBL
LigandPNGBDBM50607681(CHEMBL5218552)
Affinity DataKd:  2.5nMAssay Description:Binding affinity to human recombinant His-tagged ADCY10 assessed as dissociation constant and measured for 600 sec by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenylate cyclase type 10(Homo sapiens (Human))
Tri-Institutional Institutional Therapeutics Discovery Institute

Curated by ChEMBL
LigandPNGBDBM50607676(CHEMBL5218698)
Affinity DataKd:  3.30nMAssay Description:Binding affinity to human recombinant His-tagged ADCY10 assessed as dissociation constant and measured for 600 sec by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenylate cyclase type 10(Homo sapiens (Human))
Tri-Institutional Institutional Therapeutics Discovery Institute

Curated by ChEMBL
LigandPNGBDBM50607680(CHEMBL5218702)
Affinity DataKd:  3.60nMAssay Description:Binding affinity to human recombinant His-tagged ADCY10 assessed as dissociation constant and measured for 600 sec by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenylate cyclase type 10(Homo sapiens (Human))
Tri-Institutional Institutional Therapeutics Discovery Institute

Curated by ChEMBL
LigandPNGBDBM50607684(CHEMBL5219443)
Affinity DataKd:  3.70nMAssay Description:Binding affinity to human recombinant His-tagged ADCY10 assessed as dissociation constant and measured for 600 sec by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenylate cyclase type 10(Homo sapiens (Human))
Tri-Institutional Institutional Therapeutics Discovery Institute

Curated by ChEMBL
LigandPNGBDBM50607677(CHEMBL5220632)
Affinity DataKd:  4.70nMAssay Description:Binding affinity to human recombinant His-tagged ADCY10 assessed as dissociation constant and measured for 600 sec by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenylate cyclase type 10(Homo sapiens (Human))
Tri-Institutional Institutional Therapeutics Discovery Institute

Curated by ChEMBL
LigandPNGBDBM50607678(CHEMBL5218878)
Affinity DataKd:  5.5nMAssay Description:Binding affinity to human recombinant His-tagged ADCY10 assessed as dissociation constant and measured for 600 sec by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenylate cyclase type 1(Bos taurus)
Food And Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010259(Acetic acid 10,10b-dihydroxy-6-{2-[3-(4-hydroxy-ph...)
Affinity DataKd:  9nMAssay Description:Displacement of [125I]-6-IHPP-Fsk from adenylate cyclase of bovine brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1(Bos taurus)
Food And Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010260(CHEMBL107566 | [2-(2-Bromo-acetylamino)-ethyl]-car...)
Affinity DataKd:  10nMAssay Description:Binding activity against Adenylate cyclase in bovine brain membrane using [125I]-6-IHPP-Fsk as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1(Bos taurus)
Food And Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010270(Acetic acid 6-[2-(2-bromo-acetylamino)-ethylcarbam...)
Affinity DataKd:  10nMAssay Description:Binding activity against Adenylate cyclase in bovine brain membrane using [125I]-6-IHPP-Fsk as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1(Bos taurus)
Food And Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010265(CHEMBL327142 | {2-[3-(4-Hydroxy-phenyl)-propionyla...)
Affinity DataKd:  13nMAssay Description:Displacement of [125I]-6-IHPP-Fsk from adenylate cyclase of bovine brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1(Bos taurus)
Food And Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010261((3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10...)
Affinity DataKd:  29nMAssay Description:Displacement of [125I]-6-IHPP-Fsk from adenylate cyclase of bovine brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1(Bos taurus)
Food And Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010274(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6-(2-...)
Affinity DataKd:  34nMAssay Description:Displacement of [125I]-6-IHPP-Fsk from adenylate cyclase of bovine brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1(Bos taurus)
Food And Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010273(CHEMBL111738 | {7-[3-(4-Hydroxy-phenyl)-propionyla...)
Affinity DataKd:  53nMAssay Description:Displacement of [125I]-6-IHPP-Fsk from adenylate cyclase of bovine brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1(Bos taurus)
Food And Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010271(CHEMBL111425 | {4-[3-(4-Hydroxy-phenyl)-propionyla...)
Affinity DataKd:  60nMAssay Description:Displacement of [125I]-6-IHPP-Fsk from adenylate cyclase of bovine brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1(Bos taurus)
Food And Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010269(CHEMBL327672 | [2-(4-Hydroxy-phenyl)-ethyl]-carbam...)
Affinity DataKd:  61nMAssay Description:Displacement of [125I]-6-IHPP-Fsk from adenylate cyclase of bovine brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1(Bos taurus)
Food And Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010262(CHEMBL326703 | {4-[3-(4-Hydroxy-phenyl)-propionyla...)
Affinity DataKd:  80nMAssay Description:Displacement of [125I]-6-IHPP-Fsk from adenylate cyclase of bovine brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1(Bos taurus)
Food And Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010266(CHEMBL324659 | {6-[3-(4-Hydroxy-phenyl)-propionyla...)
Affinity DataKd:  82nMAssay Description:Displacement of [125I]-6-IHPP-Fsk from adenylate cyclase of bovine brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1(Bos taurus)
Food And Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010272(CHEMBL322952 | {6-[3-(4-Hydroxy-phenyl)-propionyla...)
Affinity DataKd:  94nMAssay Description:Displacement of [125I]-6-IHPP-Fsk from adenylate cyclase of bovine brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1(Bos taurus)
Food And Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010268((2-Amino-ethyl)-carbamic acid (3R,4aR,5S,6S,6aS,10...)
Affinity DataKd:  98nMAssay Description:Displacement of [125I]-6-IHPP-Fsk from adenylate cyclase of bovine brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1(Bos taurus)
Food And Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010264((2-Isothiocyanato-ethyl)-carbamic acid 6,10,10b-tr...)
Affinity DataKd:  110nMAssay Description:Binding activity against Adenylate cyclase in bovine brain membrane using [125I]-6-IHPP-Fsk as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1(Bos taurus)
Food And Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010263(Acetic acid 10,10b-dihydroxy-6-(2-isothiocyanato-e...)
Affinity DataKd:  130nMAssay Description:Binding activity against Adenylate cyclase in bovine brain membrane using [125I]-6-IHPP-Fsk as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1(Bos taurus)
Food And Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010275(CHEMBL324463 | {2-[3-(4-Hydroxy-phenyl)-propionyla...)
Affinity DataKd:  174nMAssay Description:Displacement of [125I]-6-IHPP-Fsk from adenylate cyclase of bovine brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 10(Homo sapiens (Human))
Tri-Institutional Institutional Therapeutics Discovery Institute

Curated by ChEMBL
LigandPNGBDBM50577242(CHEMBL4854762)
Affinity DataKd:  176nMAssay Description:Binding affinity to human recombinant His-tagged ADCY10 assessed as dissociation constant and measured for 600 sec by SPR analysisMore data for this Ligand-Target Pair
TargetAdenylate cyclase type 1(Bos taurus)
Food And Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010267(CHEMBL92719 | [2-(4-Hydroxy-phenyl)-ethyl]-carbami...)
Affinity DataKd:  236nMAssay Description:Displacement of [125I]-6-IHPP-Fsk from adenylate cyclase of bovine brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226415(CHEMBL3142312)
Affinity DataKi:  0.880nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226412(CHEMBL3142332)
Affinity DataKi:  1.70nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226410(CHEMBL3142318)
Affinity DataKi:  1.70nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226411(CHEMBL3142329)
Affinity DataKi:  1.90nMAssay Description:Binding affinity against sigma receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 2(Rattus norvegicus)
Novo Nordisk

Curated by PDSP Ki Database
LigandPNGBDBM81778(CAS_132421 | NNC-756 | NSC_132421)
Affinity DataKi:  2.20nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226417(CHEMBL3142331)
Affinity DataKi:  2.5nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226413(CHEMBL2369777)
Affinity DataKi:  2.60nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 2(Rattus norvegicus)
Novo Nordisk

Curated by PDSP Ki Database
LigandPNGBDBM50010709(5-Benzofuran-7-yl-8-chloro-3-methyl-2,3,4,5-tetrah...)
Affinity DataKi:  2.80nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226416(CHEMBL2369525)
Affinity DataKi:  3.90nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226414(CHEMBL2369778)
Affinity DataKi:  4.20nMAssay Description:Binding affinity against sigma receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226418(CHEMBL3142313)
Affinity DataKi:  7.80nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 2(Rattus norvegicus)
Novo Nordisk

Curated by PDSP Ki Database
LigandPNGBDBM81779(CAS_164252 | NNC-687 | NSC_164252)
Affinity DataKi:  9.10nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144001(3-{4-[1-(2',4'-Dichloro-biphenyl-4-ylcarbamoyl)-he...)
Affinity DataKi:  14nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144020(3-{4-[1-(4-Benzofuran-2-yl-phenylcarbamoyl)-heptyl...)
Affinity DataKi:  17nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144015(3-{4-[2-(4-Benzofuran-2-yl-phenylcarbamoyl)-octyl]...)
Affinity DataKi:  20nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50222264(CHEMBL552736)
Affinity DataKi:  22nMAssay Description:Inhibitory activity against Dopamine sensitive adenylate cyclase in ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144008(3-{4-[2-(4-Benzofuran-2-yl-phenylcarbamoyl)-2-(4-t...)
Affinity DataKi:  29nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50222266(CHEMBL369006)
Affinity DataKi:  33nMAssay Description:Inhibitory activity against Dopamine sensitive adenylate cyclase in ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144002(3-{4-[2-(4-tert-Butyl-phenyl)-2-(2',4'-dichloro-bi...)
Affinity DataKi:  33nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 2(Rattus norvegicus)
Novo Nordisk

Curated by PDSP Ki Database
LigandPNGBDBM82247(8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...)
Affinity DataKi:  39.9nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144008(3-{4-[2-(4-Benzofuran-2-yl-phenylcarbamoyl)-2-(4-t...)
Affinity DataKi:  69nMAssay Description:In vitro inhibitory activity against glucagon induced monkey adenylate cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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