Affinity DataKd: 0.490nMAssay Description:Binding affinity to human BRD3 bromodomain 2 (G306 to P416 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.520nMAssay Description:Binding affinity to human BRD3 bromodomain 1 (P24 to E144 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.650nMAssay Description:Binding affinity to human partial length BRD3 bromodomain 2 (G306 to P416 residues) expressed in bacterial expression system after 1 hr by bromoscan ...More data for this Ligand-Target Pair
Affinity DataKd: 0.660nMAssay Description:Binding affinity to BRD3 bromodomain 1/2 (unknown origin) after 1 hr by bromoscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.690nMAssay Description:Binding affinity to human partial length BRD3 bromodomain 2 (G306 to P416 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.730nMAssay Description:Binding affinity to human partial length BRD3 bromodomain 1/2 (P24 to P416 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: <1nMAssay Description:Binding affinity to human partial length BRD3 bromodomain 1 (P24 to E144 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: <1nMAssay Description:Binding affinity to human partial length BRD3 bromodomain 1 and 2 (P24 to P416 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: <1nMAssay Description:Binding affinity to human partial length BRD3 bromodomain 2 (G306 to P416 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 1nMAssay Description:Binding affinity to human partial length BRD3 BD2 (G306 to P416 residues) expressed in bacterial expression system by bromoscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.70nMAssay Description:Binding affinity to human partial length BRD3 bromodomain 1 (P24 to E144 residues) expressed in bacterial expression system after 1 hr by bromoscan a...More data for this Ligand-Target Pair
Affinity DataKd: 2nMAssay Description:Binding affinity to human partial length BRD3 bromodomain 1 (P24 to E144 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.60nMAssay Description:Binding affinity to human partial length BRD3 BD2 (G306 to P416 residues) expressed in bacterial expression system by bromoscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 4nMAssay Description:Binding affinity to full length BRD3 BD1 in human HuT78 cell lysates incubated for 45 mins by liquid chromatography-mass spectrometry based chemoprot...More data for this Ligand-Target Pair
Affinity DataKd: 5nMAssay Description:Binding affinity to human partial length BRD3 BD 2 (G306 to P416 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 6.30nMAssay Description:Binding affinity to BRD3 BD2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 3 [326-398](Homo sapiens (Human))
The Regents Of The University Of Michigan
US Patent
The Regents Of The University Of Michigan
US Patent
Affinity DataKd: 11nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
Affinity DataKd: 11nMAssay Description:Inhibition of His-tagged BRPF1 (626 to 740 residues) (unknown origin) preincubated for 15 mins followed by addition of C-terminal biotinylated synthe...More data for this Ligand-Target Pair
Affinity DataKd: 12nMAssay Description:Binding affinity to biotinylated BRD3 BD2 (306 to 417 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferomet...More data for this Ligand-Target Pair
Affinity DataKd: 12nMAssay Description:Binding affinity to human partial length BRD3 BD1 (P24 to E144 residues) expressed in bacterial expression system by bromoscan assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 3 [24-144,306-416](Homo sapiens (Human))
Dana-Farber Cancer Institute
Dana-Farber Cancer Institute
Affinity DataKd: 14nMAssay Description:Binding affinity to biotinylated BRD3 BD1 (24 to 144 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferometr...More data for this Ligand-Target Pair
Affinity DataKd: 16nMAssay Description:Binding affinity to biotinylated BRD3 BD2 (306 to 417 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferomet...More data for this Ligand-Target Pair
Affinity DataKd: 16nMAssay Description:Binding affinity to human partial length BRD3 bromodomain 1 (P24 to E144 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 3 [51-123](Homo sapiens (Human))
The Regents Of The University Of Michigan
US Patent
The Regents Of The University Of Michigan
US Patent
Affinity DataKd: 17nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 3 [51-123](Homo sapiens (Human))
The Regents Of The University Of Michigan
US Patent
The Regents Of The University Of Michigan
US Patent
Affinity DataKd: 18nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
Affinity DataKd: 18nMAssay Description:Binding affinity to biotinylated BRD3 BD1 (24 to 144 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferometr...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 3 [51-123](Homo sapiens (Human))
The Regents Of The University Of Michigan
US Patent
The Regents Of The University Of Michigan
US Patent
Affinity DataKd: 18nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
Affinity DataKd: 19nMAssay Description:Binding affinity to N-terminal portion of human Brd3 containing bromodomain BD12 expressed in Escherichia coli by isothermal titration calorimetric a...More data for this Ligand-Target Pair
Affinity DataKd: 19nMAssay Description:Binding affinity to His6-tagged BRD3 expressed in Escherichia coli by isothermal colorimetric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 19nMAssay Description:Binding affinity to human partial length DNA-tagged BRD3 BD2 expressed in bacterial by BROMOscan methodMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 3 [326-398](Homo sapiens (Human))
The Regents Of The University Of Michigan
US Patent
The Regents Of The University Of Michigan
US Patent
Affinity DataKd: 19nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
Affinity DataKd: 20nMAssay Description:Binding affinity to human partial length BRD3 BD1 expressed in bacterial expression system assessed as dissociation constant by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 20nMAssay Description:Binding affinity to His6-tagged BRD3 (1 to 475 aa) (unknown origin) by SPR methodMore data for this Ligand-Target Pair
Affinity DataKd: 20nMAssay Description:Displacement of biotinylated acetylated peptide from recombinant human partial length BRD3 bromodomain 1/2 (P24 to P416 residues) expressed in Escher...More data for this Ligand-Target Pair
Affinity DataKd: 21nMAssay Description:Displacement of biotinylated acetylated peptide from recombinant human partial length BRD3 bromodomain 1 (P24 to E144 residues) expressed in Escheric...More data for this Ligand-Target Pair
Affinity DataKd: 21nMAssay Description:Displacement of biotinylated acetylated peptide from recombinant human partial length BRD3 bromodomain 2 (G306 to P416 residues) expressed in Escheri...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 3 [51-123](Homo sapiens (Human))
The Regents Of The University Of Michigan
US Patent
The Regents Of The University Of Michigan
US Patent
Affinity DataKd: 21nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 3 [326-398](Homo sapiens (Human))
The Regents Of The University Of Michigan
US Patent
The Regents Of The University Of Michigan
US Patent
Affinity DataKd: 21nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
Affinity DataKd: 22nMAssay Description:Binding affinity to human partial length BRD3-BD1 (P24 to E144 residues) expressed in bacterial expression system by BROMOscan methodMore data for this Ligand-Target Pair
Affinity DataKd: 23nMAssay Description:Binding affinity to human partial length BRD3-BD2 (G306 to P416 residues) expressed in bacterial expression system by BROMOscan methodMore data for this Ligand-Target Pair
Affinity DataKd: 25nMAssay Description:Binding affinity to BRD3 BD1 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Affinity DataKd: 26nMAssay Description:Binding affinity to His6-fused BRD3 BD2 (unknown origin) assessed as dissociation constant in PBS incubated for 1 hrs by biolayer interferometry anal...More data for this Ligand-Target Pair
Affinity DataKd: 29nMAssay Description:Inhibition of His-tagged BRPF1 (626 to 740 residues) (unknown origin) preincubated for 15 mins followed by addition of C-terminal biotinylated synthe...More data for this Ligand-Target Pair
Affinity DataKd: 30nMAssay Description:Binding affinity to biotinylated BRD3 BD1 (24 to 144 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferometr...More data for this Ligand-Target Pair
Affinity DataKd: 37nMAssay Description:Binding affinity to human BRD3 domain 1 assessed as dissociation constant by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
Affinity DataKd: 41nMAssay Description:Binding affinity to biotinylated BRD3 BD2 (306 to 417 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferomet...More data for this Ligand-Target Pair
Affinity DataKd: 41nMAssay Description:Binding affinity to biotinylated BRD3 BD2 (306 to 417 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferomet...More data for this Ligand-Target Pair