Compile Data Set for Download or QSAR
maximum 50k data
Found 68 Enz. Inhib. hit(s) with Target = 'C-C motif chemokine 2'
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50331728(CHEMBL1289316 | N-(2-((3S,4S)-1-(cis-4-(benzo[d][1...)
Affinity DataKd:  0.230nMAssay Description:Displacement of [3H]INCB3344 from human CCR2 receptor expressed in human U2OS cell membranes assessed as association and dissociation of radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50331728(CHEMBL1289316 | N-(2-((3S,4S)-1-(cis-4-(benzo[d][1...)
Affinity DataKd:  0.720nMAssay Description:Displacement of [3H]INCB3344 from human CCR2 receptor expressed in human U2OS cell membranes assessed as association and dissociation of compound by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50331728(CHEMBL1289316 | N-(2-((3S,4S)-1-(cis-4-(benzo[d][1...)
Affinity DataKd:  0.900nMAssay Description:Displacement of [3H]INCB3344 from human CCR2 receptor expressed in human U2OS cell membranes by saturation binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50331728(CHEMBL1289316 | N-(2-((3S,4S)-1-(cis-4-(benzo[d][1...)
Affinity DataKd:  1.20nMAssay Description:Displacement of [3H]INCB3344 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50585055(CHEMBL5081237)
Affinity DataKd:  1.67E+3nMAssay Description:Binding affinity to human CCL2 assessed as dissociation constant incubated for 3 mins by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50017345(CHEMBL3288260)
Affinity DataKd:  6.10E+4nMAssay Description:Binding affinity to human recombinant CCL2 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50017346(CHEMBL3288258)
Affinity DataKd:  2.50E+8nMAssay Description:Binding affinity to human recombinant CCL2 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50017347(CHEMBL3288259)
Affinity DataKd:  2.50E+8nMAssay Description:Binding affinity to human recombinant CCL2 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50440552(CHEMBL2426340)
Affinity DataKi:  3.60nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50440556(CHEMBL2426334)
Affinity DataKi:  3.90nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50440549(CHEMBL2426351)
Affinity DataKi:  6.10nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50440557(CHEMBL2426335)
Affinity DataKi:  6.30nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50257898((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)
Affinity DataKi:  6.80nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50440552(CHEMBL2426340)
Affinity DataKi:  7.20nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50440552(CHEMBL2426340)
Affinity DataKi:  7.20nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50440551(CHEMBL2426354)
Affinity DataKi:  18nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50440558(CHEMBL2426336)
Affinity DataKi:  27nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50440550(CHEMBL2426352)
Affinity DataKi:  29nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50257900((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)
Affinity DataKi:  31nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50440545(CHEMBL2426345)
Affinity DataKi:  33nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50440559(CHEMBL2426337)
Affinity DataKi:  35nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50440546(CHEMBL2426346)
Affinity DataKi:  43nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50257992((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(2,3-...)
Affinity DataKi:  50nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50440554(CHEMBL2426357)
Affinity DataKi:  54nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50440553(CHEMBL2426356)
Affinity DataKi:  55nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50440548(CHEMBL2426348)
Affinity DataKi:  70nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50440547(CHEMBL2426347)
Affinity DataKi:  86nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50257792((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(cycl...)
Affinity DataKi:  110nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50440555(CHEMBL2426333)
Affinity DataKi:  130nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50440544(CHEMBL2426344)
Affinity DataKi:  134nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50440542(CHEMBL2426342)
Affinity DataKi:  437nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50440543(CHEMBL2426343)
Affinity DataKi:  2.40E+3nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM14027(5-(1,4-diazepan-1-ylsulfonyl)isoquinoline | 5-(1,4...)
Affinity DataIC50:  6.92E+3nMAssay Description:Inhibition of MCP1-mediated human THP cell migrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM14029((R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXA...)
Affinity DataIC50:  2.63E+3nMAssay Description:Inhibition of MCP1-mediated human THP cell migrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50417674(CHEMBL1643361)
Affinity DataIC50: >3.16E+4nMAssay Description:Inhibition of MCP1-mediated human THP cell migrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM14031(5-(1,4-diazepane-1-sulfonyl)-1,2-dihydroisoquinoli...)
Affinity DataIC50:  6.92E+3nMAssay Description:Inhibition of MCP1-mediated human THP cell migrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50607739(CHEMBL5221111)
Affinity DataIC50:  5.01E+3nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50607742(CHEMBL5218824)
Affinity DataIC50:  3.16E+3nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50607743(CHEMBL5218922)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50607744(CHEMBL5220904)
Affinity DataIC50:  631nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50607745(CHEMBL5220501)
Affinity DataIC50:  631nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50607746(CHEMBL5220753)
Affinity DataIC50:  631nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50607747(CHEMBL5220077)
Affinity DataIC50:  398nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50607748(CHEMBL5220993)
Affinity DataIC50:  1.59E+3nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50607749(CHEMBL5219089)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50607750(CHEMBL5220275)
Affinity DataIC50:  631nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50607751(CHEMBL5219599)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50607752(CHEMBL5220099)
Affinity DataIC50:  398nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50607753(CHEMBL5219077)
Affinity DataIC50:  158nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50607754(CHEMBL5218619)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Displayed 1 to 50 (of 68 total ) | Next | Last >>
Jump to: