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Found 3453 Enz. Inhib. hit(s) with Target = 'Glutaminase kidney isoform, mitochondrial'
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574392(CHEMBL4849357)
Affinity DataKd:  24nMAssay Description:Binding affinity to human GLS1 expressed in Escherichia coli strain BL21 (DE3) assessed as dissociation constant by surface plasmon resonance analysi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574392(CHEMBL4849357)
Affinity DataKd:  37nMAssay Description:Binding affinity to human GLS1 expressed in Escherichia coli strain BL21 (DE3) by ITC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605217(CHEMBL5194638)
Affinity DataKd:  52nMAssay Description:Binding affinity to human GLS1 assessed as dissociation constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509188(CHEMBL4566446)
Affinity DataKd:  68nMAssay Description:Binding affinity to human GLS1 expressed in Escherichia coli strain BL21 (DE3)pLysS by SPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605215(CHEMBL5178036)
Affinity DataKd:  81nMAssay Description:Binding affinity to human GLS1 assessed as dissociation constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM109086(US10793535, Cmpd ID 727 | US8604016, 670 | US99382...)
Affinity DataKd:  92nMAssay Description:Binding affinity to human GLS1 expressed in Escherichia coli strain BL21 (DE3)pLysS by SPR assayMore data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM109086(US10793535, Cmpd ID 727 | US8604016, 670 | US99382...)
Affinity DataKd:  105nMAssay Description:Binding affinity to human GLS1 expressed in Escherichia coli strain BL21 (DE3) by ITC analysisMore data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM109086(US10793535, Cmpd ID 727 | US8604016, 670 | US99382...)
Affinity DataKd:  106nMAssay Description:Binding affinity to human GLS1 assessed as dissociation constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50512566(CHEMBL4444708)
Affinity DataKd:  142nMAssay Description:Binding affinity to human KGA assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50400050(CHEMBL2177757 | US10793535, Cmpd ID 1 | US11191732...)
Affinity DataKd:  200nMAssay Description:Binding affinity to recombinant human C-terminal His-tagged GLS1 after 3 hrs in presence of glycine by GDH coupled assayMore data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509187(CHEMBL4526354)
Affinity DataKd:  350nMAssay Description:Binding affinity to human GLS1 expressed in Escherichia coli strain BL21 (DE3)pLysS by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509184(CHEMBL4593229)
Affinity DataKd:  450nMAssay Description:Binding affinity to human GLS1 expressed in Escherichia coli strain BL21 (DE3)pLysS by fluorescence polarization binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509184(CHEMBL4593229)
Affinity DataKd:  610nMAssay Description:Binding affinity to human GLS1 expressed in Escherichia coli strain BL21 (DE3)pLysS by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50400050(CHEMBL2177757 | US10793535, Cmpd ID 1 | US11191732...)
Affinity DataKd:  4.30E+3nMAssay Description:Binding affinity to human GLS1 expressed in Escherichia coli strain BL21 (DE3)pLysS by SPR assayMore data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232186(CHEMBL4092049)
Affinity DataKd:  4.95E+3nMAssay Description:Binding affinity to NT-647-NHS-labelled KGA (unknown origin) after 10 mins by microscale thermophoresis methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM108460(CHEMBL2178393 | US11191732, Example 1 | US8604016,...)
Affinity DataKi:  2.00E+3nMAssay Description:Uncompetitive inhibition of human kidney glutaminase (124 to 669) assessed as reduction of glutamine hydrolysis by double-reciprocal plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47186(US8604016, 46 | US9938267, Cmpd ID 46)
Affinity DataIC50: >5.00E+4nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47187(US8604016, 47 | US9938267, Cmpd ID 47)
Affinity DataIC50:  8.30E+3nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47189(US8604016, 68 | US9938267, Cmpd ID 68)
Affinity DataIC50:  4.90E+3nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47190(US8604016, 80 | US9938267, Cmpd ID 80)
Affinity DataIC50:  1.80E+3nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47191(US8604016, 81 | US9938267, Cmpd ID 81)
Affinity DataIC50:  1.00E+4nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47192(US8604016, 89)
Affinity DataIC50: >2.00E+4nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47194(US8604016, 126)
Affinity DataIC50:  5.80E+3nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47195(US8604016, 127)
Affinity DataIC50:  1.80E+3nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47196(US8604016, 128)
Affinity DataIC50:  3.20E+4nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47198(US8604016, 138)
Affinity DataIC50:  750nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47199(US8604016, 141)
Affinity DataIC50:  1.70E+3nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47200(BDBM47201 | US8604016, 143)
Affinity DataIC50:  570nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47200(BDBM47201 | US8604016, 143)
Affinity DataIC50: >2.00E+4nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47202(US8604016, 147)
Affinity DataIC50:  620nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47204(US8604016, 153 | US9938267, Cmpd ID 153)
Affinity DataIC50:  1.00E+3nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47205(US8604016, 154 | US9938267, Cmpd ID 154)
Affinity DataIC50:  1.90E+4nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47206(US8604016, 169)
Affinity DataIC50:  710nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47207(BDBM108612 | US8604016, 186 | US9938267, Cmpd ID 1...)
Affinity DataIC50:  3.10E+3nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47208(US8604016, 223)
Affinity DataIC50: >2.00E+4nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47209(US8604016, 224 | US9938267, Cmpd ID 223)
Affinity DataIC50: >2.00E+4nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47210(US8604016, 225)
Affinity DataIC50: >2.00E+4nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47213(US8604016, 226)
Affinity DataIC50:  2.30E+3nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47214(US8604016, 243)
Affinity DataIC50:  2.70E+3nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47215(US8604016, 322 | US9938267, Cmpd ID 322)
Affinity DataIC50:  2.80E+3nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47216(US8604016, 340 | US9938267, Cmpd ID 340)
Affinity DataIC50:  96nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47217(US8604016, 349 | US9938267, Cmpd ID 349)
Affinity DataIC50:  120nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47218(US8604016, 351)
Affinity DataIC50:  110nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47219(BDBM108664 | US8604016, 369 | US9938267, Cmpd ID 3...)
Affinity DataIC50:  810nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47220(US9938267, Cmpd ID 390)
Affinity DataIC50:  42nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47221(US8604016, 477 | US9938267, Cmpd ID 477)
Affinity DataIC50:  5nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47223(US8604016, 519)
Affinity DataIC50:  9nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47225(BDBM108725 | US8604016, 637 | US9938267, Cmpd ID 6...)
Affinity DataIC50: >2.00E+4nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47226(US8604016, 638 | US9938267, Cmpd ID 638)
Affinity DataIC50:  480nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM47227(US8604016, 639)
Affinity DataIC50:  170nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
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