Found 5360 Enz. Inhib. hit(s) with Target = 'Monoglyceride lipase' 
Affinity DataKd: 1.40nMAssay Description:The ThermoFluor (TF) assay is a 384-well microplate-based binding assay that measures thermal stability of proteins1,2. The experiments were carried ...More data for this Ligand-Target Pair
Affinity DataKd: 1.5nMAssay Description:Binding affinity to human His-tagged MAGL assessed as dissociation constant by surface plasmon resonance assayMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKd: 710nMAssay Description:Binding affinity to MAGL (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of human recombinant MAGL assessed as dissociation constant using 4-NPA as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of human recombinant MAGL assessed as dissociation constant using 4-NPA as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of human recombinant MAGL assessed as dissociation constant using 4-NPA as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Competitive inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrate assessed as inhibition constant by Michaelis-Menten analysisMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Competitive inhibition of human recombinant MAGL using varying concentration of 4-nitrophenylacetate as substrate incubated for 30 mins by microplate...More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Competitive inhibition of human recombinant MAGL at 31.25 nM to 125 nM pre-incubated for 5 mins before MAGL substrate addition and further incubated ...More data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Competitive inhibition of human recombinant MAGL using varying concentration of 4-nitrophenylacetate as substrate incubated for 30 mins by microplate...More data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Competitive inhibition of human recombinant MAGL using varying concentration of 4-nitrophenylacetate as substrate incubated for 30 mins by microplate...More data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Competitive inhibition of human recombinant MAGL using varying concentration of 4-nitrophenylacetate as substrate incubated for 30 mins by microplate...More data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Competitive inhibition of human recombinant MAGL using 4-NPA as substrate after 30 mins by Michaelis-Menten-based plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Mixed inhibition MAGL (unknown origin) using 4-nitrophenyl acetate as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 75.7nMAssay Description:Irreversible inhibition of human MAGL using p-nitrophenylpropionate as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 412nMAssay Description:Competitive inhibition of recombinant human MAGL using 4-NPA as substrate after 30 mins by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 650nMAssay Description:Competitive inhibition of human recombinant MAGL using 4-NPA substrate incubated for 30 mins by Michaelis-Menten kinetics analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.18E+4nMAssay Description:Inhibition of Sprague-Dawley rat MGLMore data for this Ligand-Target Pair
Affinity DataKi: 3.90E+4nMAssay Description:Inhibition of Sprague-Dawley rat MGLMore data for this Ligand-Target Pair
Affinity DataKi: 4.00E+4nMAssay Description:Non-competitive inhibition of human recombinant MAGL assessed as 7-hydroxycoumarin level using umbelliferyl arachidonate as substrate by luminescence...More data for this Ligand-Target Pair
Affinity DataKi: 5.87E+4nMAssay Description:Inhibition of Sprague-Dawley rat MGLMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of MAGL in human U937 cell homogenates using [3H]-2OG as substrate preincubated for 15 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 155nMAssay Description:Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 2.95E+4nMAssay Description:Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 9.55E+4nMAssay Description:Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 6.92E+4nMAssay Description:Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 7.41E+3nMAssay Description:Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 355nMAssay Description:Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 4.27E+3nMAssay Description:Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 5.13E+3nMAssay Description:Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 3.72E+3nMAssay Description:Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 6.03E+3nMAssay Description:Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 3.02E+3nMAssay Description:Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 2.19E+3nMAssay Description:Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 5.37E+3nMAssay Description:Inhibition of human recombinant MAGL using [3H]-2-OG as substrate after 10 mins by liquid scintillation counterMore data for this Ligand-Target Pair
