Compile Data Set for Download or QSAR
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Found 455 Enz. Inhib. hit(s) with Target = 'NAD-dependent protein deacylase sirtuin-5, mitochondrial'
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255700(CHEMBL4091790)
Affinity DataKd:  0.0100nMAssay Description:Binding affinity to human N-terminal biotinylated SIRT5 by surface plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255714(CHEMBL4064460)
Affinity DataKd:  0.120nMAssay Description:Inhibition of human recombinant N-terminal Strep2-tagged SIRT5 expressed in Escherichia coli BL21 (DE3) using Abz-GVLK(glutaryl)AY(NO2)GV-NH2 as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50576715(CHEMBL4870282)
Affinity DataKd:  2.47E+3nMAssay Description:Binding affinity to chip-immobilized recombinant human SIRT5 measured after 300 secs by surface plasmon resonance methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50196032((N-[(2-tert-butylbenzenesulfonyl)phenyl]-2,3,4-tri...)
Affinity DataKd:  4.63E+3nMAssay Description:Binding affinity to human N-terminal His-tagged SIRT5 (34 to 302 residues) expressed in Escherichia coli at 600 uM by isothermal titration calorimetr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50598628(CHEMBL5194061)
Affinity DataKd:  5.78E+3nMAssay Description:Binding affinity to SIRT5 (unknown origin) assessed as desuccinylation activity by measuring dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50598627(CHEMBL5186482)
Affinity DataKd:  8.20E+3nMAssay Description:Binding affinity to SIRT5 (unknown origin) assessed as desuccinylation activity by measuring dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50591387(CHEMBL5171546)
Affinity DataKd:  2.40E+4nMAssay Description:Binding affinity to N-terminal his-tagged human SIRT5 (34 to 302 residues) expressed in Escherichia coli assessed as dissociation constant using CPS1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50591387(CHEMBL5171546)
Affinity DataKd:  2.80E+4nMAssay Description:Binding affinity to N-terminal his-tagged human SIRT5 (34 to 302 residues) expressed in Escherichia coli assessed as dissociation constant using NAD+...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50591386(CHEMBL5171187)
Affinity DataKd:  2.80E+4nMAssay Description:Binding affinity to N-terminal his-tagged human SIRT5 (34 to 302 residues) expressed in Escherichia coli assessed as dissociation constant by microsc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50591387(CHEMBL5171546)
Affinity DataKd:  8.30E+4nMAssay Description:Binding affinity to N-terminal his-tagged human SIRT5 (34 to 302 residues) expressed in Escherichia coli assessed as dissociation constant by microsc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50598638(CHEMBL5199270)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to SIRT5 (unknown origin) assessed as deglutarylase activity by measuring inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255692(CHEMBL4100475)
Affinity DataKi:  3.5nMAssay Description:Antagonist activity at human TLR4 expressed in mouse RAW blue cells assessed as inhibition of LPS-induced NF-kappaB activation-mediated SEAP producti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255691(CHEMBL4092751)
Affinity DataKi:  3.5nMAssay Description:Inhibition of human recombinant N-terminal Strep2-tagged SIRT5 expressed in Escherichia coli BL21 (DE3) using Abz-GVLK(glutaryl)AY(NO2)GV-NH2 as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255693(CHEMBL4073655)
Affinity DataKi:  3.5nMAssay Description:Inhibition of human recombinant N-terminal Strep2-tagged SIRT5 expressed in Escherichia coli BL21 (DE3) using Abz-GVLK(glutaryl)AY(NO2)GV-NH2 as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255690(CHEMBL4068735)
Affinity DataKi:  3.5nMAssay Description:Inhibition of SIRT5 (unknown origin) using GGQSLK[succ]FGKG as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255730(CHEMBL4065067)
Affinity DataKi:  3.5nMAssay Description:Inhibition of human recombinant N-terminal Strep2-tagged SIRT5 expressed in Escherichia coli BL21 (DE3) using Abz-GVLK(glutaryl)AY(NO2)GV-NH2 as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50540057(CHEMBL4636862)
Affinity DataKi:  6nMAssay Description:Binding affinity to SIRT5 (unknown origin) assessed as deglutarylase activity by measuring inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255710(CHEMBL4091258)
Affinity DataKi:  7nMAssay Description:Inhibition of human recombinant N-terminal Strep2-tagged SIRT5 expressed in Escherichia coli BL21 (DE3) using Abz-GVLK(glutaryl)AY(NO2)GV-NH2 as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50598639(CHEMBL5209031)
Affinity DataKi:  7nMAssay Description:Binding affinity to SIRT5 (unknown origin) assessed as deglutarylase activity by measuring inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255714(CHEMBL4064460)
Affinity DataKi:  14nMAssay Description:Inhibition of human recombinant N-terminal Strep2-tagged SIRT5 expressed in Escherichia coli BL21 (DE3) using Abz-GVLK(glutaryl)AY(NO2)GV-NH2 as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50598635(CHEMBL5172115)
Affinity DataKi:  22nMAssay Description:Binding affinity to SIRT5 (unknown origin) assessed as deglutarylase activity by measuring inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255740(CHEMBL4100351)
Affinity DataKi:  23nMAssay Description:Inhibition of human recombinant N-terminal Strep2-tagged SIRT5 expressed in Escherichia coli BL21 (DE3) using Abz-GVLK(glutaryl)AY(NO2)GV-NH2 as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50598634(CHEMBL5188575)
Affinity DataKi:  37nMAssay Description:Binding affinity to SIRT5 (unknown origin) assessed as deglutarylase activity by measuring inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255726(CHEMBL4085990)
Affinity DataKi:  83nMAssay Description:Competitive inhibition of human recombinant N-terminal Strep2-tagged SIRT5 expressed in Escherichia coli BL21 (DE3) using Abz-GVLK(glutaryl)AY(NO2)GV...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255644(CHEMBL4079212)
Affinity DataKi:  135nMAssay Description:Competitive inhibition of human recombinant N-terminal Strep2-tagged SIRT5 expressed in Escherichia coli BL21 (DE3) using Abz-GVLK(glutaryl)AY(NO2)GV...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50255725(CHEMBL4068365)
Affinity DataKi:  263nMAssay Description:Inhibition of human recombinant N-terminal Strep2-tagged SIRT5 expressed in Escherichia coli BL21 (DE3) using Abz-GVLK(glutaryl)AY(NO2)GV-NH2 as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50598630(CHEMBL5194780)
Affinity DataKi:  4.30E+3nMAssay Description:Binding affinity to SIRT5 (unknown origin) assessed as desuccinylation activity by measuring inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50574075(CHEMBL4856582)
Affinity DataKi:  4.30E+3nMAssay Description:Inhibition of SIRT5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50598631(CHEMBL5197707)
Affinity DataKi:  1.06E+4nMAssay Description:Binding affinity to SIRT5 (unknown origin) assessed as desuccinylation activity by measuring inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50598629(CHEMBL5175993)
Affinity DataKi:  1.72E+4nMAssay Description:Binding affinity to SIRT5 (unknown origin) assessed as desuccinylation activity by measuring inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50598628(CHEMBL5194061)
Affinity DataKi:  3.81E+4nMAssay Description:Binding affinity to SIRT5 (unknown origin) assessed as desuccinylation activity by measuring inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50598627(CHEMBL5186482)
Affinity DataKi:  1.00E+5nMAssay Description:Binding affinity to SIRT5 (unknown origin) assessed as desuccinylation activity by measuring inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50576715(CHEMBL4870282)
Affinity DataKi:  1.22E+5nMAssay Description:Inhibition of human recombinant SIRT5 assessed as inhibition of substrate desuccinylation using Fluor de Lys-Succinyl green peptide as substrate in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM234205(US9359293, TA)
Affinity DataIC50: >2.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM234206(US9359293, TB)
Affinity DataIC50: >2.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM234207(US9359293, TH)
Affinity DataIC50: >2.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM234208(US9359293, TM)
Affinity DataIC50: >2.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50156760((E)-2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human SIRT5 assessed as reduction in desuccinylase activity using KQTAR(SuK)STGGKA substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50216689(2-cyano-3-(5-(2,5-dichlorophenyl)furan-2-yl)-N-(qu...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human SIRT5 assessed as reduction in desuccinylase activity using KQTAR(SuK)STGGKA substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM29590(1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one | CHEMBL8...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human SIRT5 assessed as reduction in desuccinylase activity using KQTAR(SuK)STGGKA substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM27507(3-Pyridinecarboxamide | CHEMBL1140 | NAM | niacina...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human SIRT5 assessed as reduction in desuccinylase activity using KQTAR(SuK)STGGKA substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50336799(5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of human SIRT5 assessed as reduction in desuccinylase activity using KQTAR(SuK)STGGKA substrateMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50336799(5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of human recombinant SIRT5 isoform 1 (34 to 302 amino acids) expressed in Escherichia coli BL21 (DE3) codon plus RIL cells assessed as red...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50336799(5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of SIRT5 (unknown origin) using (DABCYL)ISGASE(SuK)DIVHSE(EDANS)G peptide substrate incubated for 1 hrs followed by 1 hr incubation with t...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50336799(5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of SIRT5 (unknown origin) using (DABCYL)ISGASE(SuK)DIVHSE(EDANS)G peptide substrate incubated for 1 hrs followed by 1 hr incubation with t...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50106875(CHEMBL3601367)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human SIRT5 using CH3CONH-AR-(Nepsilon-succinyl-lysine)-ST-CONH2 as substrate after 5 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50106871(CHEMBL3601368)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human SIRT5 using CH3CONH-AR-(Nepsilon-succinyl-lysine)-ST-CONH2 as substrate after 5 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50106876(CHEMBL3601369)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human SIRT5 using CH3CONH-AR-(Nepsilon-succinyl-lysine)-ST-CONH2 as substrate after 5 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50106877(CHEMBL3601371)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human SIRT5 using CH3CONH-AR-(Nepsilon-succinyl-lysine)-ST-CONH2 as substrate after 5 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50168905(CHEMBL3805692)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (37 to 310 residues) expressed in Escherichia coli using Ac-Lys(Succ)-AMC as substrate in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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