Found 260 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase haspin' 
Affinity DataKd: 0.0190nMAssay Description:Binding affinity to a TEV-cleavable N-terminal His6-tagged human recombinant haspin (470 to 798 residues) assessed as dissociation constantMore data for this Ligand-Target Pair
Affinity DataKd: 0.0190nMpH: 7.5Assay Description:All measurements were performed in HEPES (50 mm, pH 7.5) containing NaCl (150 mm), Tween-20 (0.005%) and DTT (5 mm) according to a previously publish...More data for this Ligand-Target Pair
Affinity DataKd: 0.0190nMAssay Description:Binding affinity to haspin (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Affinity DataKd: 0.100nMpH: 7.5Assay Description:Association kinetics (Kon): All measurements were performed in HEPES (50 mM, pH 7.5) containing NaCl (150 mM), Tween-20 (0.005%) and DTT (5 mM) accor...More data for this Ligand-Target Pair
Affinity DataKd: 0.120nMpH: 7.5Assay Description:All measurements were performed in HEPES (50 mm, pH 7.5) containing NaCl (150 mm), Tween-20 (0.005%) and DTT (5 mm) according to a previously publish...More data for this Ligand-Target Pair
Affinity DataKd: 0.140nMpH: 7.5Assay Description:All measurements were performed in HEPES (50 mm, pH 7.5) containing NaCl (150 mm), Tween-20 (0.005%) and DTT (5 mm) according to a previously publish...More data for this Ligand-Target Pair
Affinity DataKd: 0.420nMAssay Description:Binding affinity to N-terminal his6-tagged human recombinant Haspin (470 to 798 residues) assessed as dissociation constantMore data for this Ligand-Target Pair
Affinity DataKd: 0.5nMpH: 7.5Assay Description:All measurements were performed in HEPES (50 mm, pH 7.5) containing NaCl (150 mm), Tween-20 (0.005%) and DTT (5 mm) according to a previously publish...More data for this Ligand-Target Pair
Affinity DataKd: 2.84nMpH: 7.5Assay Description:Association kinetics (Kon): All measurements were performed in HEPES (50 mM, pH 7.5) containing NaCl (150 mM), Tween-20 (0.005%) and DTT (5 mM) accor...More data for this Ligand-Target Pair
Affinity DataKd: 4nMAssay Description:Binding affinity to a TEV-cleavable N-terminal His6-tagged human recombinant haspin (470 to 798 residues) assessed as dissociation constantMore data for this Ligand-Target Pair
Affinity DataKd: 8.40nMpH: 7.5Assay Description:All measurements were performed in HEPES (50 mm, pH 7.5) containing NaCl (150 mm), Tween-20 (0.005%) and DTT (5 mm) according to a previously publish...More data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Binding affinity to human HASPINMore data for this Ligand-Target Pair
Affinity DataKd: 11nMpH: 7.5Assay Description:All measurements were performed in HEPES (50 mm, pH 7.5) containing NaCl (150 mm), Tween-20 (0.005%) and DTT (5 mm) according to a previously publish...More data for this Ligand-Target Pair
Affinity DataKd: 14.9nMpH: 7.5Assay Description:Association kinetics (Kon): All measurements were performed in HEPES (50 mM, pH 7.5) containing NaCl (150 mM), Tween-20 (0.005%) and DTT (5 mM) accor...More data for this Ligand-Target Pair
Affinity DataKd: 15nMAssay Description:Binding affinity to wild-type human partial length HASPIN (I452 to K798 residues) expressed in mammalian expression system measured after 1 hr by com...More data for this Ligand-Target Pair
Affinity DataKd: 86nMAssay Description:Binding affinity to partial length wild-type human HASPIN (I452 to K798 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
Affinity DataKd: 150nMAssay Description:Binding affinity to N-terminal his6-tagged human recombinant Haspin (470 to 798 residues) assessed as dissociation constantMore data for this Ligand-Target Pair
Affinity DataKd: 170nMAssay Description:Binding affinity to N-terminal his6-tagged human recombinant Haspin (470 to 798 residues) assessed as dissociation constantMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin [465-798](Homo sapiens (Human))
George Washington University
George Washington University
Affinity DataKd: 297nMpH: 7.5 T: 2°CAssay Description:For ERK1 and ERK2, the buffer contained 20 mM HEPES (pH 7.5), 150 mM NaCl and 0.5 mM TCEP. For haspin, the buffer contained 20 mM HEPES (pH 7.5), 250...More data for this Ligand-Target Pair
Affinity DataKd: 780nMAssay Description:Displacement of polymer supported probe 25 binding to GSG2 in human THP-1 cell lysates preincubated for 45 mins under shaking condition followed by p...More data for this Ligand-Target Pair
Affinity DataKd: 1.00E+3nMAssay Description:Binding affinity to human HASPIN assessed as dissociation constant by KdELECT Discover assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.70E+3nMAssay Description:Binding affinity to human HASPINMore data for this Ligand-Target Pair
Affinity DataKd: >1.50E+4nMAssay Description:Binding affinity to a TEV-cleavable N-terminal His6-tagged human recombinant haspin (470 to 798 residues) assessed as dissociation constantMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin [465-798](Homo sapiens (Human))
George Washington University
George Washington University
Affinity DataIC50: 398nMAssay Description:The IC50 values of selected kinases were determined using either Z'LYTE, Adapta or LanthaScreen assays.More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of haspin (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of haspin (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Haspin (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Haspin (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Haspin (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Haspin (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Haspin (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human HaspinMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human Haspin using histone H3 as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 255nMAssay Description:Inhibition of Haspin (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 259nMAssay Description:Inhibition of Haspin (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of partial-length human wild type HASPIN expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Haspin assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of haspin (V473 to K798) (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of haspin (V473 to K798) (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of haspin (V473 to K798) (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of haspin (V473 to K798) (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Haspin (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 830nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
