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Found 161 Enz. Inhib. hit(s) with Target = 'Small conductance calcium-activated potassium channel protein 1'
TargetSmall conductance calcium-activated potassium channel protein 1(Homo sapiens (Human))
Neurosearch

Curated by ChEMBL
LigandPNGBDBM50275090((1H-Benzoimidazol-2-yl)-(6,7-dichloro-1,2,3,4-tetr...)
Affinity DataKd:  54nMAssay Description:Inhibition of human SK1 channel by inside-out patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50260153(Apamin | CHEMBL525408 | Octadecapeptide venom)
Affinity DataKi:  0.00400nMAssay Description:Displacement of [125I]apamin from Wistar rat cortical apamin-sensitive siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50476799(CHEMBL397282)
Affinity DataKi:  23nMAssay Description:Displacement of [125I]apamin from SK channel in Wistar rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50476809(CHEMBL394773)
Affinity DataKi:  33nMAssay Description:Displacement of [125I]apamin from SK channel in Wistar rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50476802(CHEMBL395568)
Affinity DataKi:  35nMAssay Description:Displacement of [125I]apamin from SK channel in Wistar rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50476800(CHEMBL242790)
Affinity DataKi:  42nMAssay Description:Displacement of [125I]apamin from SK channel in Wistar rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50476798(CHEMBL242789)
Affinity DataKi:  90nMAssay Description:Displacement of [125I]apamin from SK channel in Wistar rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50476801(CHEMBL241952)
Affinity DataKi:  106nMAssay Description:Displacement of [125I]apamin from SK channel in Wistar rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50476807(CHEMBL242791)
Affinity DataKi:  132nMAssay Description:Displacement of [125I]apamin from SK channel in Wistar rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50476803(CHEMBL242579)
Affinity DataKi:  150nMAssay Description:Displacement of [125I]apamin from SK channel in Wistar rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50476813(CHEMBL241953)
Affinity DataKi:  163nMAssay Description:Displacement of [125I]apamin from SK channel in Wistar rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50476810(CHEMBL242578)
Affinity DataKi:  164nMAssay Description:Displacement of [125I]apamin from SK channel in Wistar rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50476805(CHEMBL390923)
Affinity DataKi:  196nMAssay Description:Displacement of [125I]apamin from SK channel in Wistar rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50048403(1,1'-(Deca-4,6-diyne-1,10-diyl)bis(4-amino-2-methy...)
Affinity DataKi:  221nMAssay Description:Displacement of [125I]apamin from SK channel in Wistar rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50476806(CHEMBL244261)
Affinity DataKi:  280nMAssay Description:Displacement of [125I]apamin from SK channel in Wistar rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50476804(CHEMBL390924)
Affinity DataKi:  438nMAssay Description:Displacement of [125I]apamin from SK channel in Wistar rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50476033(CHEMBL215533)
Affinity DataKi:  730nMAssay Description:Displacement of [125I]apamin from Wistar rat cortical apamin-sensitive siteMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50476031(CHEMBL215029)
Affinity DataKi:  910nMAssay Description:Displacement of [125I]apamin from Wistar rat cortical apamin-sensitive siteMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50476814(CHEMBL241951)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [125I]apamin from SK channel in Wistar rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50199404(1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-2,2-dimethy...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [125I]apamin from SK channel in Wistar rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50199404(1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-2,2-dimethy...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [125I]apamin from Wistar rat cortical apamin-sensitive siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50476812(CHEMBL242577)
Affinity DataKi:  1.47E+3nMAssay Description:Displacement of [125I]apamin from SK channel in Wistar rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50475213(CHEMBL365744)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of [125I]apamin binding to calcium-activated potassium (SK) channel of rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50199404(1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-2,2-dimethy...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of [125I]apamin binding to calcium-activated potassium (SK) channel of rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50476808(CHEMBL242372)
Affinity DataKi:  1.69E+3nMAssay Description:Displacement of [125I]apamin from SK channel in Wistar rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50476811(CHEMBL429280)
Affinity DataKi:  1.96E+3nMAssay Description:Displacement of [125I]apamin from SK channel in Wistar rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50476029(CHEMBL215037)
Affinity DataKi:  2.20E+3nMAssay Description:Displacement of [125I]apamin from Wistar rat cortical apamin-sensitive siteMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50475209(CHEMBL186011)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibition of [125I]apamin binding to calcium-activated potassium (SK) channel of rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50475206(CHEMBL190220)
Affinity DataKi:  3.60E+3nMAssay Description:Inhibition of [125I]apamin binding to calcium-activated potassium (SK) channel of rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50476028(CHEMBL386836 | N-Methyl-Noscapine)
Affinity DataKi:  3.60E+3nMAssay Description:Displacement of [125I]apamin from Wistar rat cortical apamin-sensitive siteMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50260153(Apamin | CHEMBL525408 | Octadecapeptide venom)
Affinity DataKi:  3.80E+3nMAssay Description:Inhibition of [125I]apamin binding to calcium-activated potassium (SK) channel of rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50475212(CHEMBL190992)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of [125I]apamin binding to calcium-activated potassium (SK) channel of rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50476032(CHEMBL214787)
Affinity DataKi:  5.40E+3nMAssay Description:Displacement of [125I]apamin from Wistar rat cortical apamin-sensitive siteMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50475208(CHEMBL188644)
Affinity DataKi:  5.50E+3nMAssay Description:Inhibition of [125I]apamin binding to calcium-activated potassium (SK) channel of rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50476030(CHEMBL215382)
Affinity DataKi:  5.80E+3nMAssay Description:Displacement of [125I]apamin from Wistar rat cortical apamin-sensitive siteMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50475211(CHEMBL187736)
Affinity DataKi:  6.80E+3nMAssay Description:Inhibition of [125I]apamin binding to calcium-activated potassium (SK) channel of rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50475207(CHEMBL427162)
Affinity DataKi:  7.60E+3nMAssay Description:Inhibition of [125I]apamin binding to calcium-activated potassium (SK) channel of rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50475210(CHEMBL190003)
Affinity DataKi:  9.30E+3nMAssay Description:Inhibition of [125I]apamin binding to calcium-activated potassium (SK) channel of rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1(RAT)
Pudue Pharma Discovery Research

Curated by PDSP Ki Database
LigandPNGBDBM50133817(4-(3-Chloro-pyridin-2-yl)-piperazine-1-carboxylic ...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1(Homo sapiens (Human))
Neurosearch

Curated by ChEMBL
LigandPNGBDBM50275792(CHEMBL452406 | N-benzyl-5-chloropyrazolo[1,5-a]pyr...)
Affinity DataIC50:  1.19E+3nMAssay Description:Inhibition of Kca2.1 channel (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1(Homo sapiens (Human))
Neurosearch

Curated by ChEMBL
LigandPNGBDBM50275960(5-chloro-N-(thiophen-2-ylmethyl)pyrazolo[1,5-a]pyr...)
Affinity DataIC50:  300nMAssay Description:Inhibition of Kca2.1 channel (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rattus norvegicus)
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50155248(CHEMBL3774478)
Affinity DataIC50:  0.0160nMAssay Description:Displacement of [125I]apamin from rat cerebral cortex small conductance calcium-activated potassium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1(RAT)
Pudue Pharma Discovery Research

Curated by PDSP Ki Database
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]apamin from SK+Ca channel in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1(Homo sapiens (Human))
Neurosearch

Curated by ChEMBL
LigandPNGBDBM50061977(17,25-diazonia-2,9-diazaheptacyclo[23.6.2.24,7.210...)
Affinity DataIC50:  3nMAssay Description:Inhibition of hSK1 calcium activated potassium channel (SKCa channel)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1(Homo sapiens (Human))
Neurosearch

Curated by ChEMBL
LigandPNGBDBM50092131(1,7-diazonia-15,21-diazapentacyclo[20.6.2.27,14.08...)
Affinity DataIC50:  1nMAssay Description:Inhibition of hSK1 calcium activated potassium channel (SKCa channel); Range is 1-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1(Homo sapiens (Human))
Neurosearch

Curated by ChEMBL
LigandPNGBDBM50377863(AG-525 | CHEMBL257156)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of SK1 expressed in CHO FlipIn cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1(Homo sapiens (Human))
Neurosearch

Curated by ChEMBL
LigandPNGBDBM50264020(CHEMBL489770 | GNF-PF-4773 | N-(4-(pyridin-2-yl)th...)
Affinity DataIC50:  43nMAssay Description:Inhibition of Kca2.1 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1(Homo sapiens (Human))
Neurosearch

Curated by ChEMBL
LigandPNGBDBM50263327(CHEMBL476339 | N-(4-methylpyridin-2-yl)-4-(pyridin...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Kca2.1 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1(RAT)
Pudue Pharma Discovery Research

Curated by PDSP Ki Database
LigandPNGBDBM50260153(Apamin | CHEMBL525408 | Octadecapeptide venom)
Affinity DataIC50:  0.0240nMAssay Description:Inhibition of rat SK Calcium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 1(Homo sapiens (Human))
Neurosearch

Curated by ChEMBL
LigandPNGBDBM168436(US9675591, SKA-19)
Affinity DataEC50: >1.00E+5nMpH: 7.35 T: 2°CAssay Description:All experiments were conducted at room temperature (22-24° C.) with an EPC-10 amplifier and Pulse software (HEKA, Lambrecht/Pfalz, Germany) in the wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
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