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Found 86 Enz. Inhib. hit(s) with Target = 'Tubulin beta-1 chain'
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150589((E)-(S)-4-{[(S)-3,3-Dimethyl-2-((S)-3-methyl-2-met...)
Affinity DataKd:  260nMAssay Description:Binding affinity towards tubulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150585((E)-(S)-2,5-Dimethyl-4-{methyl-[(R)-3-methyl-2-((S...)
Affinity DataKd:  700nMAssay Description:Binding affinity towards tubulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50152123(4-({2-[3-(4-Methoxy-phenyl)-3-methyl-2-methylamino...)
Affinity DataKd:  700nMAssay Description:Binding affinity towards tubulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50152118(4-[(2-{2-[(2-Hydroxy-ethyl)-methyl-amino]-3-methyl...)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity towards tubulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50152135(4-{[2-(3-Cyclohexyl-3-methyl-2-methylamino-butyryl...)
Affinity DataKd:  1.20E+3nMAssay Description:Binding affinity towards tubulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50152105(4-{[3,3-Dimethyl-2-(3-methyl-2-methylamino-3-pheny...)
Affinity DataKd:  4.00E+3nMAssay Description:Binding affinity towards tubulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50152133(4-{[3,3-Dimethyl-2-(3-methyl-2-methylamino-3-pheny...)
Affinity DataKd:  4.00E+3nMAssay Description:Binding affinity towards tubulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50151100((3,5-Dimethoxy-phenyl)-(6-methoxy-1H-indol-3-yl)-m...)
Affinity DataIC50:  2.69E+3nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)
Affinity DataIC50:  2.03E+3nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50151101((6-Methoxy-1H-indol-3-yl)-(3,4,5-trimethoxy-phenyl...)
Affinity DataIC50:  2.18E+3nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50151097((6-Methoxy-2-methyl-1H-indol-3-yl)-(3,4,5-trimetho...)
Affinity DataIC50:  900nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50151115((5-Methoxy-indol-1-yl)-(3,4,5-trimethoxy-phenyl)-m...)
Affinity DataIC50:  3.76E+3nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50151098((5-Methoxy-2-methyl-indol-1-yl)-(3,4,5-trimethoxy-...)
Affinity DataIC50:  3.31E+3nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50095325(CHEMBL150590 | [2-Methoxy-5-(3,4,5-trimethoxy-phen...)
Affinity DataIC50:  4.10E+4nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159289((E)-3-(3'',5''-Difluoro-4''-methoxyphenyl)-1-(2',3...)
Affinity DataIC50:  3.10E+4nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159290(5-[(Z)-2-(4-Methoxy-phenyl)-vinyl]-1,2,3-trimethyl...)
Affinity DataIC50:  650nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50070103((E)-1-(2',5'-Dimethoxyphenyl)-3-(4''-N,N-Dimethyla...)
Affinity DataIC50:  1.00E+4nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159291((E)-3-(3''-Fluoro-4''-methoxyphenyl)-1-(2',3',4'-t...)
Affinity DataIC50:  7.90E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50095321(2-Methoxy-5-(3,4,5-trimethoxy-benzyloxy)-benzaldeh...)
Affinity DataIC50:  560nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159292(2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-but-1...)
Affinity DataIC50:  130nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159293((E)-3-(3,4,5-Trihydroxy-phenyl)-1-(2,3,4-trimethox...)
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159294(2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-prope...)
Affinity DataIC50:  130nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50095316(3-[2-Methoxy-5-(3,4,5-trimethoxy-phenoxymethyl)-ph...)
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50070104((2E)-3-(3-Hydroxy-4-methoxyphenyl)-1-(3,4,5-trimet...)
Affinity DataIC50:  620nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159295((E)-3-(3''-Hydroxy-4''-methoxyphenyl)-1-(20,30,40-...)
Affinity DataIC50:  450nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159296(5-[(Z)-2-(3,4-Dimethyl-phenyl)-vinyl]-1,2,3-trimet...)
Affinity DataIC50:  2.00E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159297((E)-3-(3''-Fluoro-4''-methoxyphenyl)-1-(3',4',5'-t...)
Affinity DataIC50:  1.20E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50095320(2-Methoxy-5-(3,4,5-trimethoxy-benzyloxy)-phenol | ...)
Affinity DataIC50:  2.10E+4nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50006677(1,2,3-Trimethoxy-5-[(Z)-2-(4-methoxy-phenyl)-vinyl...)
Affinity DataIC50:  200nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159298(5-[(Z)-2-(3-Fluoro-4-methoxy-phenyl)-vinyl]-2,3-di...)
Affinity DataIC50:  1.25E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159299(1,2,3-Trifluoro-5-[(Z)-2-(3-fluoro-4-methoxy-pheny...)
Affinity DataIC50:  5.50E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159300((E)-3-(3''-Fluoro-4''-methoxyphenyl)-2-methyl-1-(3...)
Affinity DataIC50:  650nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50095317(2-Methoxy-5-(3,4,5-trimethoxy-phenoxymethyl)-pheno...)
Affinity DataIC50:  7.20E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50095322(CHEMBL153243 | [2-Methoxy-5-(3,4,5-trimethoxy-benz...)
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159302(3-(3''-Hydroxy-4''-methoxyphenyl)-2-methyl-1-(3',4...)
Affinity DataIC50:  4.00E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159301((Z)-3-(3''-Fluoro-4''-methoxyphenyl)-2-methoxy-1-(...)
Affinity DataIC50:  470nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50006675(5-[(Z)-2-(4-Ethyl-phenyl)-vinyl]-1,2,3-trimethoxy-...)
Affinity DataIC50:  3.40E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)
Affinity DataIC50:  180nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159303((E)-3-(4''-Methoxy-3''-nitrophenyl)-2-methyl-1-(3'...)
Affinity DataIC50: >1.00E+4nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50009561((E)-5-(3,4,5-trimethoxystyryl)-2-methoxyphenol | 2...)
Affinity DataIC50:  5.00E+4nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159306(1,2,3-Triethoxy-5-[(Z)-2-(3-fluoro-4-methoxy-pheny...)
Affinity DataIC50:  1.20E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159305(2-Methoxy-5-[(Z)-2-(3,4,5-triethoxy-phenyl)-vinyl]...)
Affinity DataIC50:  500nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159309(1,2,3-Trimethoxy-5-[(Z)-2-(4-methoxy-phenyl)-1-met...)
Affinity DataIC50:  1.30E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159304((Z)-2-methoxy-5-(3,4,5-trifluorostyryl)phenol | 2-...)
Affinity DataIC50:  4.50E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159308((E)-3-(3''-Hydroxy-4''-methoxyphenyl)-2-methyl-1-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159307(2-Methoxy-5-[(Z)-2-(3,4,5-trimethyl-phenyl)-vinyl]...)
Affinity DataIC50:  120nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159311(5-[(Z)-2-(3-Fluoro-4-methoxy-phenyl)-vinyl]-1,2,3-...)
Affinity DataIC50:  700nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159312((Z)-3-(3'',5''-Difluoro-4''-methoxyphenyl)-2-metho...)
Affinity DataIC50:  1.70E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159310(5-[(Z)-2-(3,4-Dimethyl-phenyl)-vinyl]-2-methoxy-ph...)
Affinity DataIC50:  3.10E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159313((Z)-3-(3''-Hydroxy-4''-methoxyphenyl)-2-methoxy-1-...)
Affinity DataIC50:  510nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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