Compile Data Set for Download or QSAR
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Found 2047 Enz. Inhib. hit(s) with Target = '5'-nucleotidase'
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM223071((E)-N'-(4'-Chlorobenzylidene)isonicotinohy...)
Affinity DataIC50:  1.67E+3nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Rattus norvegicus (Rat))
Comsats Institute Of Information Technology

LigandPNGBDBM26994(CHEMBL68253 | H2NSO3H | sulfamic acid)
Affinity DataIC50:  7.73E+4nMpH: 7.4 T: 2°CAssay Description:The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM223073((E)-N'-(4'-Fluorobenzylidene)isonicotinohy...)
Affinity DataIC50:  6.76E+3nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM223074((E)-N'-(4'-Methoxybenzylidene)isonicotinoh...)
Affinity DataIC50:  1.38E+4nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM223075((E)-N'-(2'-hydroxybenzylidene)isonicotinoh...)
Affinity DataIC50:  1.34E+3nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM223076((E)-N'-(3'-Nitrobenzylidene)isonicotinohyd...)
Affinity DataIC50:  1.90E+3nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM223077((E)-N'-(4'-Hydroxy-3-methoxybenzylidene)is...)
Affinity DataIC50:  680nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM223078((E)-N'-(Pyridin-4'-ylmethylene)isonicotino...)
Affinity DataIC50:  2.12E+3nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM223079((E)-N'-(Pyridin-3'-ylmethylene)isonicotino...)
Affinity DataIC50:  210nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM223080((E)-N'-(1-(3-(4-fluorophenyl)-5-phenyl-4,5-dih...)
Affinity DataIC50:  190nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM26994(CHEMBL68253 | H2NSO3H | sulfamic acid)
Affinity DataIC50:  4.21E+4nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Rattus norvegicus (Rat))
Comsats Institute Of Information Technology

LigandPNGBDBM223071((E)-N'-(4'-Chlorobenzylidene)isonicotinohy...)
Affinity DataIC50:  1.08E+3nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Rattus norvegicus (Rat))
Comsats Institute Of Information Technology

LigandPNGBDBM223072((E)-N'-(4'-Bromobenzylidene)isonicotinohyd...)
Affinity DataIC50:  7.13E+3nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Rattus norvegicus (Rat))
Comsats Institute Of Information Technology

LigandPNGBDBM223073((E)-N'-(4'-Fluorobenzylidene)isonicotinohy...)
Affinity DataIC50:  440nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Rattus norvegicus (Rat))
Comsats Institute Of Information Technology

LigandPNGBDBM223074((E)-N'-(4'-Methoxybenzylidene)isonicotinoh...)
Affinity DataIC50:  310nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Rattus norvegicus (Rat))
Comsats Institute Of Information Technology

LigandPNGBDBM223075((E)-N'-(2'-hydroxybenzylidene)isonicotinoh...)
Affinity DataIC50:  450nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Rattus norvegicus (Rat))
Comsats Institute Of Information Technology

LigandPNGBDBM223076((E)-N'-(3'-Nitrobenzylidene)isonicotinohyd...)
Affinity DataIC50:  210nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Rattus norvegicus (Rat))
Comsats Institute Of Information Technology

LigandPNGBDBM223077((E)-N'-(4'-Hydroxy-3-methoxybenzylidene)is...)
Affinity DataIC50:  140nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Rattus norvegicus (Rat))
Comsats Institute Of Information Technology

LigandPNGBDBM223078((E)-N'-(Pyridin-4'-ylmethylene)isonicotino...)
Affinity DataIC50:  2.89E+3nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Rattus norvegicus (Rat))
Comsats Institute Of Information Technology

LigandPNGBDBM223079((E)-N'-(Pyridin-3'-ylmethylene)isonicotino...)
Affinity DataIC50:  3.01E+3nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Rattus norvegicus (Rat))
Comsats Institute Of Information Technology

LigandPNGBDBM223080((E)-N'-(1-(3-(4-fluorophenyl)-5-phenyl-4,5-dih...)
Affinity DataIC50:  360nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Rattus norvegicus (Rat))
Comsats Institute Of Information Technology

LigandPNGBDBM26994(CHEMBL68253 | H2NSO3H | sulfamic acid)
Affinity DataIC50:  7.73E+4nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM222258((Z)-4-(2-((E)-4-(2-chlorophenyl)-1-morpholino-2-ox...)
Affinity DataIC50:  1.16E+4nMpH: 7.4 T: 2°CAssay Description:The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM222259((Z)-4-(2-((E)-4-(2,4-dichlorophenyl)-1-morpholino-...)
Affinity DataIC50:  3.32E+3nMpH: 7.4 T: 2°CAssay Description:The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM222261((Z)-4-(2-((E)-4-(4-methoxyphenyl)-1-morpholino-2-o...)
Affinity DataIC50:  3.42E+3nMpH: 7.4 T: 2°CAssay Description:The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM222262((Z)-4-(2-((E)-4-(3,4-dimethoxyphenyl)-1-morpholino...)
Affinity DataIC50:  260nMpH: 7.4 T: 2°CAssay Description:The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM222263((Z)-4-(2-((E)-1-morpholino-2-oxo-4-(3,4,5-Trimetho...)
Affinity DataIC50:  1.75E+3nMpH: 7.4 T: 2°CAssay Description:The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM222266((Z)-4-(2-((E)-4-(2-bromophenyl)-1-morpholino-2-oxo...)
Affinity DataIC50:  2.92E+3nMpH: 7.4 T: 2°CAssay Description:The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM26994(CHEMBL68253 | H2NSO3H | sulfamic acid)
Affinity DataIC50:  4.21E+4nMpH: 7.4 T: 2°CAssay Description:The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Rattus norvegicus (Rat))
Comsats Institute Of Information Technology

LigandPNGBDBM222258((Z)-4-(2-((E)-4-(2-chlorophenyl)-1-morpholino-2-ox...)
Affinity DataIC50:  6.43E+3nMpH: 7.4 T: 2°CAssay Description:The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Rattus norvegicus (Rat))
Comsats Institute Of Information Technology

LigandPNGBDBM222259((Z)-4-(2-((E)-4-(2,4-dichlorophenyl)-1-morpholino-...)
Affinity DataIC50:  2.85E+3nMpH: 7.4 T: 2°CAssay Description:The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM223072((E)-N'-(4'-Bromobenzylidene)isonicotinohyd...)
Affinity DataIC50:  230nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Rattus norvegicus (Rat))
Comsats Institute Of Information Technology

LigandPNGBDBM222262((Z)-4-(2-((E)-4-(3,4-dimethoxyphenyl)-1-morpholino...)
Affinity DataIC50:  7.41E+3nMpH: 7.4 T: 2°CAssay Description:The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Rattus norvegicus (Rat))
Comsats Institute Of Information Technology

LigandPNGBDBM222263((Z)-4-(2-((E)-1-morpholino-2-oxo-4-(3,4,5-Trimetho...)
Affinity DataIC50:  680nMpH: 7.4 T: 2°CAssay Description:The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Rattus norvegicus (Rat))
Comsats Institute Of Information Technology

LigandPNGBDBM222266((Z)-4-(2-((E)-4-(2-bromophenyl)-1-morpholino-2-oxo...)
Affinity DataIC50:  2.24E+4nMpH: 7.4 T: 2°CAssay Description:The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Rattus norvegicus (Rat))
Comsats Institute Of Information Technology

LigandPNGBDBM222261((Z)-4-(2-((E)-4-(4-methoxyphenyl)-1-morpholino-2-o...)
Affinity DataIC50:  330nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase assay was optimized and performed in the same way as previously reported method with slight modifications [Sergienko et al., Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM50527134(CHEMBL4471306 | US20230295213, Compound a)
Affinity DataKi:  0.00500nMAssay Description:Inhibition of recombinant human C-terminal His-tagged CD73 (27 to 549 residues) expressed in HEK293 cells using AMP as substrate preincubated for 1 h...More data for this Ligand-Target Pair
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM50527134(CHEMBL4471306 | US20230295213, Compound a)
Affinity DataKi:  0.00500nMAssay Description:Inhibition of human CD73More data for this Ligand-Target Pair
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM50527134(CHEMBL4471306 | US20230295213, Compound a)
Affinity DataKi:  0.00500nMAssay Description:Competitive reversible inhibition of human C-terminal His6-tagged CD73 expressed in HEK293 cells using AMP as substrate preincubated with substrate f...More data for this Ligand-Target Pair
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM50527135(CHEMBL4452072)
Affinity DataKi:  0.318nMAssay Description:Inhibition of human CD73More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM50527135(CHEMBL4452072)
Affinity DataKi:  0.381nMAssay Description:Inhibition of recombinant human C-terminal His-tagged CD73 (27 to 549 residues) expressed in Sf9 cells using [2,8-3H]-AMP as substrate incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM50583394(CHEMBL5081267)
Affinity DataKi:  0.436nMAssay Description:Inhibition of human soluble CD73 assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM50583393(CHEMBL5083600)
Affinity DataKi:  0.441nMAssay Description:Inhibition of human soluble CD73 assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM50583396(CHEMBL5074970)
Affinity DataKi:  0.511nMAssay Description:Inhibition of human soluble CD73 assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM50583400(CHEMBL5078828)
Affinity DataKi:  0.626nMAssay Description:Inhibition of human soluble CD73 assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM50583392(CHEMBL5080841)
Affinity DataKi:  0.673nMAssay Description:Inhibition of human soluble CD73 assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Rattus norvegicus (Rat))
Comsats Institute Of Information Technology

LigandPNGBDBM50527135(CHEMBL4452072)
Affinity DataKi:  0.746nMAssay Description:Inhibition of recombinant rat CD73 expressed in Sf9 cells using [2,8-3H]-AMP as substrate incubated for 25 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
Target5'-nucleotidase(Rattus norvegicus (Rat))
Comsats Institute Of Information Technology

LigandPNGBDBM50527135(CHEMBL4452072)
Affinity DataKi:  0.746nMAssay Description:Inhibition of rat CD73More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM50583397(CHEMBL5086866)
Affinity DataKi:  0.848nMAssay Description:Inhibition of human soluble CD73 assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Rattus norvegicus (Rat))
Comsats Institute Of Information Technology

LigandPNGBDBM50378656(CHEMBL598619)
Affinity DataKi:  0.870nMAssay Description:Inhibition of rat ecto-5'-nucleotidase expressed in Sf9 cells by capillary electrophoresis methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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