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Found 654 Enz. Inhib. hit(s) with Target = 'Arginase-1'
TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290429((1S,2S,4S)-1-amino-4-(aminomethyl)-2-(3- boronopro...)
Affinity DataIC50:  625nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290430((1S,2S,4R)-1-amino-4-(2-aminoethyl)-2-(3- boronopr...)
Affinity DataIC50: <250nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290365((1S,2S)-1-amino-2-(3-boronopropyl)cyclopentanecarb...)
Affinity DataIC50:  625nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290366((1S,2R)-1-amino-2-(3-boronopropyl)cyclopentanecarb...)
Affinity DataIC50: >5.00E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290367((2R,3S)-3-amino-2-(3-boronopropyl)tetrahydrofuran-...)
Affinity DataIC50:  1.50E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290368((2S,3S)-3-amino-2-(3-boronopropyl)tetrahydrofuran-...)
Affinity DataIC50: <250nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290369(3-amino-2-(3-boronopropyl)tetrahydrothiophene-3-ca...)
Affinity DataIC50:  1.50E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290370((3R,4S)-4-amino-3-(3-boronopropyl)piperidine-4-car...)
Affinity DataIC50:  625nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290371((3S,4S)-4-amino-3-(3-boronopropyl)piperidine-4-car...)
Affinity DataIC50:  625nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290372((3R,4S)-3-amino-4-(3-boronopropyl)pyrrolidine-3-ca...)
Affinity DataIC50:  625nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290373((3R,4R)-3-amino-4-(3-boronopropyl)pyrrolidine-3-ca...)
Affinity DataIC50:  1.50E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290374((2R,3S)-3-amino-2-(3-boronopropyl)pyrrolidine-3-ca...)
Affinity DataIC50: >5.00E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290375((3R,4S)-3-amino-4-(3-boronopropyl)-1-isobutylpyrro...)
Affinity DataIC50:  625nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290376((3R,4S)-3-amino-1-benzyl-4-(3-boronopropyl)pyrroli...)
Affinity DataIC50:  625nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290377((3R,4S)-3-amino-4-(3-boronopropyl)-1-(pyridin-3- y...)
Affinity DataIC50:  625nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290378((3R,4S)-3-amino-1-(2-aminocyclopentyl)-4-(3- boron...)
Affinity DataIC50: <250nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290379((3R,4S)-3-amino-4-(3-boronopropyl)-1-(piperidin)-4...)
Affinity DataIC50:  625nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290380((3R,4S)-3-amino-4-(3-boronopropyl)-1-(3-(4- carbox...)
Affinity DataIC50: <250nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290381((3R,4S)-3-amino-4-(3-boronopropyl)-1-(3-(dimethyla...)
Affinity DataIC50:  3.50E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290382((3R,4S)-3-amino-4-(3-boronopropyl)-1-(piperidin-3-...)
Affinity DataIC50: <250nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290383((3R,4S)-3-amino-4-(3-boronopropyl)-1-(quinolin-4- ...)
Affinity DataIC50:  625nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290384((3R,4S)-1-((1H-imidazol-4-yl)methyl)-3-amino-4-(3-...)
Affinity DataIC50: <250nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290385((3R,4S)-3-amino-4-(3-boronopropyl)-1-(piperidin-2-...)
Affinity DataIC50: <250nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290386((3R,4S)-3-amino-4-(3-boronopropyl)-1-(3-(4- chloro...)
Affinity DataIC50:  625nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290387((3R,4S)-3-amino-4-(3-boronopropyl)-1-(7H-purin-6-y...)
Affinity DataIC50:  625nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290388((3R,4S)-3-amino-1-(2-aminoethyl)-4-(3-boronopropyl...)
Affinity DataIC50: <250nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290389(5-((3R,4S)-3-amino-4-(3-boronopropyl)-3-carboxypyr...)
Affinity DataIC50:  625nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290390((3R,4S)-3-amino-4-(3-boronopropyl)-1-(piperidin-4-...)
Affinity DataIC50:  625nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290391((3R,4S)-3-amino-4-(3-boronopropyl)-1,3'-bipyrrolid...)
Affinity DataIC50: <250nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290392((3R,4S)-3-amino-4-(3-boronopropyl)-1-(piperidin-3-...)
Affinity DataIC50: <250nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290393((3R,4S)-3-amino-4-(3-boronopropyl)-1-(pyridin-2- y...)
Affinity DataIC50:  1.50E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290394((3R,4S)-3-amino-4-(3-boronopropyl)-1-(4- carboxycy...)
Affinity DataIC50:  625nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290395((3R,4S)-3-amino-4-(3-boronopropyl)-1-((1-methyl-1H...)
Affinity DataIC50: <250nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290396((3R,4S)-3-amino-4-(3-boronopropyl)-1-(4-methylpyri...)
Affinity DataIC50:  1.50E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290397((3R,4S)-3-amino-4-(3-boronopropyl)-1-(2-(piperidin...)
Affinity DataIC50: <250nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290398((3R,4S)-3-amino-4-(3-boronopropyl)-1-(2- (diethyla...)
Affinity DataIC50: <250nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290399((3R,4S)-4-(3-boronopropyl)-3-(methylamino)pyrrolid...)
Affinity DataIC50:  625nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290400((3R,4S)-3-amino-4-(3-boronopropyl)-1-((1-methylpip...)
Affinity DataIC50: <250nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290401((3R,4S)-3-amino-4-(3-boronopropyl)-1-(pyrrolidin-2...)
Affinity DataIC50: <250nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290402((3R,4S)-3-amino-4-(3-boronopropyl)-1-(2-(pyrrolidi...)
Affinity DataIC50: <250nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290403((3R,4S)-3-amino-4-(3-boronopropyl)-1-(((S)-1,2,3,4...)
Affinity DataIC50: <250nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290404((3R,4S)-3-amino-1-(2-(benzylamino)ethyl)-4-(3- bor...)
Affinity DataIC50: <250nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290405((3R,4S)-3-amino-4-(3-boronopropyl)-1-(2-(3,4- dich...)
Affinity DataIC50: <250nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290406((3R,4S)-3-amino-4-(3-boronopropyl)-1-(4- chlorophe...)
Affinity DataIC50:  625nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290407((3R,4S)-3-amino-4-(3-boronopropyl)-1-((S)-pyrrolid...)
Affinity DataIC50: <250nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290408((3R,4S)-3-amino-1-(2-aminocyclohexyl)-4-(3- borono...)
Affinity DataIC50: <250nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290409((3R,4S)-3-amino-4-(3-boronopropyl)-1-(2-(4- chloro...)
Affinity DataIC50:  625nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290410((3R,4S)-3-amino-4-(3-boronopropyl)-1-(4- fluoroben...)
Affinity DataIC50:  625nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290411((3R,4S)-3-amino-4-(3-boronopropyl)-1-(4- methoxybe...)
Affinity DataIC50:  625nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290412((3R,4S)-3-amino-4-(3-boronopropyl)-1-(4- fluorophe...)
Affinity DataIC50:  625nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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