TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataIC50: 500nMpH: 7.5 T: 2°CAssay Description:The AMPK peptide including the sequence surrounding the phosphorylation site of AMPK (167GEFLRTSCGSP177), was synthesized at the Support Unit for Bio...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2 [ P274E](Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataIC50: 2.42E+4nMpH: 7.5 T: 2°CAssay Description:The AMPK peptide including the sequence surrounding the phosphorylation site of AMPK (167GEFLRTSCGSP177), was synthesized at the Support Unit for Bio...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKi: 1.80nMAssay Description:Inhibition of CaM-KKbetaChecked by AuthorMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKi: 15nMAssay Description:Candidates for inhibitor selectivity characterization were chosen based on an initial single-timepoint commercial kinome profiling screen performed w...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKi: 15nMAssay Description:Inhibition of CAMKK2 (unknown origin) using NUAK2 peptide as substrate measured after 30 mins in presence of [gamma32P]ATP by liquid scintillation co...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKi: 31nMAssay Description:Inhibition of CAMKK2 (unknown origin) using NUAK2 peptide as substrate measured after 30 mins in presence of [gamma32P]ATP by liquid scintillation co...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKi: 31nMAssay Description:Candidates for inhibitor selectivity characterization were chosen based on an initial single-timepoint commercial kinome profiling screen performed w...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKi: 85nMAssay Description:Inhibition of CAMKK2 (unknown origin) using NUAK2 peptide as substrate measured after 30 mins in presence of [gamma32P]ATP by liquid scintillation co...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKi: 85nMAssay Description:Candidates for inhibitor selectivity characterization were chosen based on an initial single-timepoint commercial kinome profiling screen performed w...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKi: 1.30E+4nMAssay Description:Inhibition of CaM-KKbetaChecked by AuthorMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKi: 2.97E+4nMAssay Description:Inhibition of CaM-KKbetaChecked by AuthorMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: 220nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: 2.50E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: 430nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: 2.60E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: 2.40E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: 73nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: 2.50E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: 0.160nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: 1.50E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataIC50: 127nMAssay Description:Inhibition of CaM-KKbetaChecked by AuthorMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataIC50: 200nMAssay Description:Inhibition of CaM-KKbetaChecked by AuthorMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataIC50: 10nMAssay Description:Inhibition of CAMKKbeta in the presence of 20uM ATPMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: 4.00E+4nMAssay Description:Binding affinity to CAMKK2More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: 5.80E+3nMAssay Description:Average Binding Constant for CAMKK2; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: 0.0500nMAssay Description:Average Binding Constant for CAMKK2; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: 7.50E+3nMAssay Description:Average Binding Constant for CAMKK2; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: 1.10E+3nMAssay Description:Average Binding Constant for CAMKK2; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to CAMKK2More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: 73nMAssay Description:Binding affinity to CAMKK2More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to CAMKK2More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: 790nMAssay Description:Binding affinity to CAMKK2More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: 1.50E+3nMAssay Description:Binding affinity to CAMKK2More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to CAMKK2More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: 15nMAssay Description:Binding affinity to CAMKK2More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: 23nMAssay Description:Binding constant for CAMKK2 kinase domainMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for CAMKK2 kinase domainMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: 1.40E+3nMAssay Description:Binding constant for CAMKK2 kinase domainMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for CAMKK2 kinase domainMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for CAMKK2 kinase domainMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for CAMKK2 kinase domainMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for CAMKK2 kinase domainMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: 0.160nMAssay Description:Binding constant for CAMKK2 kinase domainMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for CAMKK2 kinase domainMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for CAMKK2 kinase domainMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: 740nMAssay Description:Binding constant for CAMKK2 kinase domainMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: 4.00E+3nMAssay Description:Binding constant for CAMKK2 kinase domainMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: 1.50E+3nMAssay Description:Binding constant for CAMKK2 kinase domainMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataKd: 430nMAssay Description:Binding constant for CAMKK2 kinase domainMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Riken Systems And Structural Biology Center
Riken Systems And Structural Biology Center
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of CAMKKbetaMore data for this Ligand-Target Pair