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Found 137 Enz. Inhib. hit(s) with Target = 'Farnesyl diphosphate synthase'
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM25298((1-hydroxy-1-phosphonoheptyl)phosphonic acid | CHE...)
Affinity DataKi:  400nMAssay Description:Inhibition of Trypanosoma cruzi FPPSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341910(1-[(Benzylamino)ethyl]1,1-bisphosphonic acid | CHE...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341911(1-[(n-Non-1-ylamino)ethyl]1,1-bisphosphonic acid |...)
Affinity DataIC50:  430nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341912(1-[(n-Dec-1-ylamino)ethyl]1,1-bisphosphonic acid |...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341913(1-[(n-Undec-1-ylamino)ethyl]1,1-bisphosphonic acid...)
Affinity DataIC50:  856nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341914(1-[(n-Dodec-1-ylamino)ethyl]1,1-bisphosphonic acid...)
Affinity DataIC50:  811nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341915(1-[(n-Tetradec-1-ylamino)ethyl]1,1-bisphosphonic a...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM12576(Bisphosphonate 1 | CHEMBL923 | JMC515594 Compound ...)
Affinity DataIC50:  27nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341916(1-[(n-oct-1-ylamino)ethyl]-1,1-bisphosphonic acid ...)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341917(1-[(n-hex-1-ylamino)ethyl]-1,1-bisphosphonic acid ...)
Affinity DataIC50:  490nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341918((2-heptylamino-1-phosphono-ethyl)-phosphonic acid ...)
Affinity DataIC50:  58nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341911(1-[(n-Non-1-ylamino)ethyl]1,1-bisphosphonic acid |...)
Affinity DataIC50:  440nMAssay Description:Inhibition of Toxoplasma gondii FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341912(1-[(n-Dec-1-ylamino)ethyl]1,1-bisphosphonic acid |...)
Affinity DataIC50:  68nMAssay Description:Inhibition of Toxoplasma gondii FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341913(1-[(n-Undec-1-ylamino)ethyl]1,1-bisphosphonic acid...)
Affinity DataIC50:  868nMAssay Description:Inhibition of Toxoplasma gondii FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341914(1-[(n-Dodec-1-ylamino)ethyl]1,1-bisphosphonic acid...)
Affinity DataIC50:  93nMAssay Description:Inhibition of Toxoplasma gondii FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341915(1-[(n-Tetradec-1-ylamino)ethyl]1,1-bisphosphonic a...)
Affinity DataIC50:  292nMAssay Description:Inhibition of Toxoplasma gondii FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM12576(Bisphosphonate 1 | CHEMBL923 | JMC515594 Compound ...)
Affinity DataIC50:  74nMAssay Description:Inhibition of Toxoplasma gondii FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341917(1-[(n-hex-1-ylamino)ethyl]-1,1-bisphosphonic acid ...)
Affinity DataIC50:  140nMAssay Description:Inhibition of Toxoplasma gondii FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50444839(CHEMBL3099275)
Affinity DataIC50:  35nMAssay Description:Inhibition of Toxoplasma gondii FPPSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50444840(CHEMBL3099280)
Affinity DataIC50:  125nMAssay Description:Inhibition of Toxoplasma gondii FPPSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341918((2-heptylamino-1-phosphono-ethyl)-phosphonic acid ...)
Affinity DataIC50:  95nMAssay Description:Inhibition of Toxoplasma gondii FPPSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM12576(Bisphosphonate 1 | CHEMBL923 | JMC515594 Compound ...)
Affinity DataIC50:  74nMAssay Description:Inhibition of Toxoplasma gondii recombinant FPPS expressed in Escherichia coli using [4-14C]IPP/DMAPP/GPP as substrate after 30 mins by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50444841(CHEMBL3099277)
Affinity DataIC50:  67nMAssay Description:Inhibition of Toxoplasma gondii FPPSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50444842(CHEMBL3099278)
Affinity DataIC50:  51nMAssay Description:Inhibition of Toxoplasma gondii FPPSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50444843(CHEMBL3099279)
Affinity DataIC50:  39nMAssay Description:Inhibition of Toxoplasma gondii FPPSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426987(CHEMBL2326224)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Toxoplasma gondii FPPSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50444844(CHEMBL3099276)
Affinity DataIC50:  60nMAssay Description:Inhibition of Toxoplasma gondii FPPSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426972(CHEMBL2326227)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426973(CHEMBL2326228)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426974(CHEMBL2326229)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426975(CHEMBL2326230)
Affinity DataIC50:  6.39E+3nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426976(CHEMBL2326231)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426977(CHEMBL2326232)
Affinity DataIC50:  97nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426978(CHEMBL2326233)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426979(CHEMBL2326234)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426980(CHEMBL2326235)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426981(CHEMBL2326236)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426982(CHEMBL2326237)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426983(CHEMBL2326238)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426984(CHEMBL2326220)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426985(CHEMBL2326221)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426986(CHEMBL2326222)
Affinity DataIC50:  40nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM12576(Bisphosphonate 1 | CHEMBL923 | JMC515594 Compound ...)
Affinity DataIC50:  27nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426985(CHEMBL2326221)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Toxoplasma gondii farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426984(CHEMBL2326220)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Toxoplasma gondii farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426978(CHEMBL2326233)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Toxoplasma gondii farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426977(CHEMBL2326232)
Affinity DataIC50:  21nMAssay Description:Inhibition of Toxoplasma gondii farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426976(CHEMBL2326231)
Affinity DataIC50:  25nMAssay Description:Inhibition of Toxoplasma gondii farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426987(CHEMBL2326224)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Toxoplasma gondii farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50426988(CHEMBL2326225)
Affinity DataIC50:  1.83E+3nMAssay Description:Inhibition of Toxoplasma gondii farnesyl diphosphate synthase assessed as incorporation of [4-14C]IPP measured at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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