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Found 6546 Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4'
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM230656(US9340517, 105)
Affinity DataIC50:  3.28E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were carried out using commercial or in-house prepared hMC1R, hMC3R and hMC4R membranes and [125I] NDP-MSH, as per the hMC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM230659(US9340517, 348)
Affinity DataIC50:  2.00E+4nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were carried out using commercial or in-house prepared hMC1R, hMC3R and hMC4R membranes and [125I] NDP-MSH, as per the hMC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM230658(US9340517, 33)
Affinity DataIC50:  6.06E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were carried out using commercial or in-house prepared hMC1R, hMC3R and hMC4R membranes and [125I] NDP-MSH, as per the hMC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM230657(US9340517, 64)
Affinity DataIC50:  3.49E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were carried out using commercial or in-house prepared hMC1R, hMC3R and hMC4R membranes and [125I] NDP-MSH, as per the hMC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160159(US9040663, 5)
Affinity DataKi:  0.0550nM ΔG°:  -60.9kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160158(US9040663, 4)
Affinity DataKi:  0.0550nM ΔG°:  -60.9kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160174(US9040663, 20)
Affinity DataKi:  0.0600nM ΔG°:  -60.7kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160157(US9040663, 3)
Affinity DataKi:  0.0800nM ΔG°:  -59.9kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160175(US9040663, 21)
Affinity DataKi:  0.0850nM ΔG°:  -59.8kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM250643(US9447148, 9.11)
Affinity DataKi:  0.0950nM ΔG°:  -59.5kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160169(US9040663, 15)
Affinity DataKi:  0.145nM ΔG°:  -58.4kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160208(US9040663, 54)
Affinity DataKi:  0.25nM ΔG°:  -57.0kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160165(US9040663, 11)
Affinity DataKi:  0.25nM ΔG°:  -57.0kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160170(US9040663, 16)
Affinity DataKi:  0.25nM ΔG°:  -57.0kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160201(US9040663, 47)
Affinity DataKi:  0.300nM ΔG°:  -56.5kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160180(US9040663, 26)
Affinity DataKi:  0.300nM ΔG°:  -56.5kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160217(US9040663, 63)
Affinity DataKi:  0.350nM ΔG°:  -56.1kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM135752(US10179804, Example 137 | US10632171, Peptide No. ...)
Affinity DataKi:  0.400nMpH: 7.5Assay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160173(US9040663, 19)
Affinity DataKi:  0.400nM ΔG°:  -55.8kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM135752(US10179804, Example 137 | US10632171, Peptide No. ...)
Affinity DataKi:  0.400nM ΔG°:  -55.8kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM135736(US10179804, Example 121 | US10632171, Peptide No. ...)
Affinity DataKi:  0.400nM ΔG°:  -55.8kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM135736(US10179804, Example 121 | US10632171, Peptide No. ...)
Affinity DataKi:  0.400nMpH: 7.5Assay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160178(US9040663, 24)
Affinity DataKi:  0.450nM ΔG°:  -55.5kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160172(US9040663, 18)
Affinity DataKi:  0.5nM ΔG°:  -55.2kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160253(US9040663, 99)
Affinity DataKi:  0.5nM ΔG°:  -55.2kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160183(US9040663, 29)
Affinity DataKi:  0.5nM ΔG°:  -55.2kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160206(US9040663, 52)
Affinity DataKi:  0.600nM ΔG°:  -54.8kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160205(US9040663, 51)
Affinity DataKi:  0.600nM ΔG°:  -54.8kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160167(US9040663, 13)
Affinity DataKi:  0.600nM ΔG°:  -54.8kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM135690(US10179804, Example 75 | US10632171, Peptide No. 7...)
Affinity DataKi:  0.600nMpH: 7.5Assay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM135690(US10179804, Example 75 | US10632171, Peptide No. 7...)
Affinity DataKi:  0.600nM ΔG°:  -54.8kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160211(US9040663, 57)
Affinity DataKi:  0.650nM ΔG°:  -54.5kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160181(US9040663, 27)
Affinity DataKi:  0.667nM ΔG°:  -54.5kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM135717(US10179804, Example 102 | US10632171, Peptide No. ...)
Affinity DataKi:  0.700nM ΔG°:  -54.4kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM135717(US10179804, Example 102 | US10632171, Peptide No. ...)
Affinity DataKi:  0.700nMpH: 7.5Assay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM135630(US10179804, Example 15 | US10632171, Peptide No. 1...)
Affinity DataKi:  0.700nMpH: 7.5Assay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160177(US9040663, 23)
Affinity DataKi:  0.700nM ΔG°:  -54.4kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160163(US9040663, 9)
Affinity DataKi:  0.700nM ΔG°:  -54.4kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160156(US9040663, 2)
Affinity DataKi:  0.75nM ΔG°:  -54.2kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160252(US9040663, 98)
Affinity DataKi:  0.75nM ΔG°:  -54.2kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160251(US9040663, 97)
Affinity DataKi:  0.75nM ΔG°:  -54.2kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM250661(US9447148, 9.30)
Affinity DataKi:  0.75nM ΔG°:  -54.2kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM135753(US10179804, Example 138 | US10632171, Peptide No. ...)
Affinity DataKi:  0.800nMpH: 7.5Assay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM135753(US10179804, Example 138 | US10632171, Peptide No. ...)
Affinity DataKi:  0.800nM ΔG°:  -54.0kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160161(US9040663, 7)
Affinity DataKi:  0.833nM ΔG°:  -53.9kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160248(US9040663, 94)
Affinity DataKi:  0.900nM ΔG°:  -53.7kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160207(US9040663, 53)
Affinity DataKi:  0.950nM ΔG°:  -53.6kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM160168(US9040663, 14)
Affinity DataKi:  0.950nM ΔG°:  -53.6kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM135629(US10179804, Example 14 | US10632171, Peptide No. 1...)
Affinity DataKi:  1nM ΔG°:  -53.4kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Mimetica

US Patent
LigandPNGBDBM135754(US10179804, Example 139 | US10632171, Peptide No. ...)
Affinity DataKi:  1nM ΔG°:  -53.4kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
In DepthDetails US Patent
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