Affinity DataIC50: 3.28E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were carried out using commercial or in-house prepared hMC1R, hMC3R and hMC4R membranes and [125I] NDP-MSH, as per the hMC...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were carried out using commercial or in-house prepared hMC1R, hMC3R and hMC4R membranes and [125I] NDP-MSH, as per the hMC...More data for this Ligand-Target Pair
Affinity DataIC50: 6.06E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were carried out using commercial or in-house prepared hMC1R, hMC3R and hMC4R membranes and [125I] NDP-MSH, as per the hMC...More data for this Ligand-Target Pair
Affinity DataIC50: 3.49E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were carried out using commercial or in-house prepared hMC1R, hMC3R and hMC4R membranes and [125I] NDP-MSH, as per the hMC...More data for this Ligand-Target Pair
Affinity DataKi: 0.0550nM ΔG°: -60.9kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.0550nM ΔG°: -60.9kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.0600nM ΔG°: -60.7kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.0800nM ΔG°: -59.9kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.0850nM ΔG°: -59.8kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.0950nM ΔG°: -59.5kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Affinity DataKi: 0.145nM ΔG°: -58.4kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.25nM ΔG°: -57.0kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.25nM ΔG°: -57.0kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.25nM ΔG°: -57.0kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nM ΔG°: -56.5kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nM ΔG°: -56.5kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.350nM ΔG°: -56.1kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMpH: 7.5Assay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nM ΔG°: -55.8kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nM ΔG°: -55.8kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nM ΔG°: -55.8kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMpH: 7.5Assay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
Affinity DataKi: 0.450nM ΔG°: -55.5kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nM ΔG°: -55.2kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nM ΔG°: -55.2kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nM ΔG°: -55.2kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nM ΔG°: -54.8kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nM ΔG°: -54.8kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nM ΔG°: -54.8kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMpH: 7.5Assay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nM ΔG°: -54.8kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
Affinity DataKi: 0.650nM ΔG°: -54.5kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.667nM ΔG°: -54.5kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nM ΔG°: -54.4kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMpH: 7.5Assay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMpH: 7.5Assay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nM ΔG°: -54.4kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nM ΔG°: -54.4kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.75nM ΔG°: -54.2kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.75nM ΔG°: -54.2kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.75nM ΔG°: -54.2kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.75nM ΔG°: -54.2kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMpH: 7.5Assay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
Affinity DataKi: 0.800nM ΔG°: -54.0kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
Affinity DataKi: 0.833nM ΔG°: -53.9kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nM ΔG°: -53.7kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.950nM ΔG°: -53.6kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 0.950nM ΔG°: -53.6kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -53.4kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -53.4kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...More data for this Ligand-Target Pair