Compile Data Set for Download or QSAR
maximum 50k data
Found 493 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta'
LigandPNGBDBM25018(3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phe...)
Affinity DataIC50:  220nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM12915(2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...)
Affinity DataIC50:  2.10E+3nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25036(CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...)
Affinity DataIC50:  100nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25056(4-{6-chloroimidazo[1,2-a]pyridin-3-yl}-2-[(2-methy...)
Affinity DataIC50:  100nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)
Affinity DataIC50:  10nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM12915(2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...)
Affinity DataIC50:  2.10E+3nMpH: 7.4 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25028(4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpipera...)
Affinity DataIC50:  670nMpH: 7.5 T: 2°CAssay Description:Test compounds were added to reaction buffer containing yttrium silicate (Ysi) polylysine SPA beads (Amersham), and the enzyme was added to the assay...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM185152(STK16-IN-1)
Affinity DataIC50:  9.33E+3nMAssay Description:The enzymatic assay was performed using the LifeTechnology SelectScreen.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50326053(CHEMBL608533 | PKC-412)
Affinity DataKd:  1.40E+3nMAssay Description:Binding affinity to PIK3C2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to PIK3C2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PIK3C2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)
Affinity DataKd:  5.20E+3nMAssay Description:Binding constant for PIK3C2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PIK3C2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50326053(CHEMBL608533 | PKC-412)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PIK3C2B kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human PI3KC2beta by non-radiometric ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50042922(CHEMBL3218581)
Affinity DataIC50:  462nMAssay Description:Inhibition of human PI3KC2beta by non-radiometric ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM12915(2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...)
Affinity DataIC50:  1.04E+4nMAssay Description:Inhibition of human PI3KC2beta by non-radiometric ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50042923(CHEMBL3354566)
Affinity DataIC50:  44nMAssay Description:Inhibition of human PI3KC2beta by non-radiometric ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50042924(CHEMBL1229535)
Affinity DataIC50:  140nMAssay Description:Inhibition of human PI3KC2beta by non-radiometric ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50042925(CHEMBL3218571)
Affinity DataIC50:  370nMAssay Description:Inhibition of human PI3KC2beta by non-radiometric ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM81368(PIK90)
Affinity DataIC50:  64nMAssay Description:Inhibition of human PI3KC2beta by non-radiometric ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25028(4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpipera...)
Affinity DataIC50:  590nMAssay Description:Inhibition of human PI3KC2beta by non-radiometric ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human PI3KC2beta by non-radiometric ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50315213(2-(difluoromethyl)-1-(4,6-dimorpholin-4-yl-1,3,5-t...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human PI3KC2beta by non-radiometric ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50042926(CHEMBL3354565)
Affinity DataIC50:  630nMAssay Description:Inhibition of human PI3KC2beta by non-radiometric ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50042927(CHEMBL3354564)
Affinity DataIC50:  530nMAssay Description:Inhibition of human PI3KC2beta by non-radiometric ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50048416(CHEMBL3360219)
Affinity DataIC50:  4.48E+4nMAssay Description:Inhibition of human GDT-fused recombinant PI3K-C2beta assessed as residual activity by nonradiometric ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50048417(CHEMBL3360221)
Affinity DataIC50:  6.12E+4nMAssay Description:Inhibition of human GDT-fused recombinant PI3K-C2beta assessed as residual activity by nonradiometric ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50048418(CHEMBL3360227)
Affinity DataIC50:  2.88E+4nMAssay Description:Inhibition of human GDT-fused recombinant PI3K-C2beta assessed as residual activity by nonradiometric ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50048419(CHEMBL3360231)
Affinity DataIC50:  2.71E+3nMAssay Description:Inhibition of human GDT-fused recombinant PI3K-C2beta assessed as residual activity by nonradiometric ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50094951(CHEMBL3589320)
Affinity DataIC50:  2.08E+4nMAssay Description:Inhibition of Glu-tagged PI3KC2beta (unknown origin) expressed in Sf9/Baculovirus system using [gamma-33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50094952(CHEMBL3589321)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibition of Glu-tagged PI3KC2beta (unknown origin) expressed in Sf9/Baculovirus system using [gamma-33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50094953(CHEMBL3589322)
Affinity DataIC50:  1.46E+4nMAssay Description:Inhibition of Glu-tagged PI3KC2beta (unknown origin) expressed in Sf9/Baculovirus system using [gamma-33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50094954(CHEMBL3589323)
Affinity DataIC50:  8.55E+4nMAssay Description:Inhibition of Glu-tagged PI3KC2beta (unknown origin) expressed in Sf9/Baculovirus system using [gamma-33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50094955(CHEMBL3589324)
Affinity DataIC50:  5.25E+3nMAssay Description:Inhibition of Glu-tagged PI3KC2beta (unknown origin) expressed in Sf9/Baculovirus system using [gamma-33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50094956(CHEMBL3589370)
Affinity DataIC50:  2.67E+3nMAssay Description:Inhibition of Glu-tagged PI3KC2beta (unknown origin) expressed in Sf9/Baculovirus system using [gamma-33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50094942(CHEMBL3589371)
Affinity DataIC50:  4.43E+3nMAssay Description:Inhibition of Glu-tagged PI3KC2beta (unknown origin) expressed in Sf9/Baculovirus system using [gamma-33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50094943(CHEMBL3589372)
Affinity DataIC50:  9.45E+3nMAssay Description:Inhibition of Glu-tagged PI3KC2beta (unknown origin) expressed in Sf9/Baculovirus system using [gamma-33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50094944(CHEMBL3589373)
Affinity DataIC50:  7.88E+4nMAssay Description:Inhibition of Glu-tagged PI3KC2beta (unknown origin) expressed in Sf9/Baculovirus system using [gamma-33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50094945(CHEMBL3589374)
Affinity DataIC50:  2.86E+4nMAssay Description:Inhibition of Glu-tagged PI3KC2beta (unknown origin) expressed in Sf9/Baculovirus system using [gamma-33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50094946(CHEMBL3589375)
Affinity DataIC50:  8.16E+4nMAssay Description:Inhibition of Glu-tagged PI3KC2beta (unknown origin) expressed in Sf9/Baculovirus system using [gamma-33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50094947(CHEMBL3589376)
Affinity DataIC50:  9.76E+3nMAssay Description:Inhibition of Glu-tagged PI3KC2beta (unknown origin) expressed in Sf9/Baculovirus system using [gamma-33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50094948(CHEMBL3589377)
Affinity DataIC50:  8.46E+3nMAssay Description:Inhibition of Glu-tagged PI3KC2beta (unknown origin) expressed in Sf9/Baculovirus system using [gamma-33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50094949(CHEMBL3589378)
Affinity DataIC50:  8.56E+3nMAssay Description:Inhibition of Glu-tagged PI3KC2beta (unknown origin) expressed in Sf9/Baculovirus system using [gamma-33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50094950(CHEMBL3589379)
Affinity DataIC50:  8.75E+3nMAssay Description:Inhibition of Glu-tagged PI3KC2beta (unknown origin) expressed in Sf9/Baculovirus system using [gamma-33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to PIK3C2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM13535(4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to PIK3C2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to PIK3C2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50328584(1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethy...)
Affinity DataIC50:  549nMAssay Description:Inhibition of PI3K-C2 betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50326054(CHEMBL1240703)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to PIK3C2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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