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Found 296 Enz. Inhib. hit(s) with Target = 'Prostaglandin E synthase 2'
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181798(US9145380, 1)
Affinity DataIC50:  130nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181799(US9145380, 2)
Affinity DataIC50:  270nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181800(US9145380, 3)
Affinity DataIC50:  140nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181801(US9145380, 4)
Affinity DataIC50:  79nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181802(US9145380, 5)
Affinity DataIC50:  40nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181803(US9145380, 6)
Affinity DataIC50:  74nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181804(US9145380, 7)
Affinity DataIC50:  280nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181805(US9145380, 8)
Affinity DataIC50:  2.20E+3nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181806(US9145380, 9)
Affinity DataIC50:  610nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181807(US9145380, 10)
Affinity DataIC50:  450nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181808(US9145380, 11)
Affinity DataIC50:  590nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181809(US9145380, 12)
Affinity DataIC50:  1.00E+3nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181810(US9145380, 13)
Affinity DataIC50:  520nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181811(US9145380, 14)
Affinity DataIC50:  3.10E+3nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181812(US9145380, 15)
Affinity DataIC50:  7.60E+3nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181813(US9145380, 16)
Affinity DataIC50:  190nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181814(US9145380, 17)
Affinity DataIC50:  5.30E+3nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181815(US9145380, 18)
Affinity DataIC50:  44nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181816(US9145380, 19)
Affinity DataIC50:  1.40E+3nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181817(US9145380, 20)
Affinity DataIC50:  700nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181818(US9145380, 21)
Affinity DataIC50:  320nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181819(US9145380, 22)
Affinity DataIC50:  430nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181820(US9145380, 23)
Affinity DataIC50:  270nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181821(US9145380, 24)
Affinity DataIC50:  300nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181822(US9145380, 25)
Affinity DataIC50:  77nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181823(US9145380, 26)
Affinity DataIC50:  420nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181824(US9145380, 27)
Affinity DataIC50:  270nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181825(US9145380, 28)
Affinity DataIC50:  290nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181826(US9145380, 29)
Affinity DataIC50:  280nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181827(US9145380, 30)
Affinity DataIC50:  5.90E+3nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181828(US9145380, 31)
Affinity DataIC50:  5.70E+3nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181829(US9145380, 32)
Affinity DataIC50:  5.10E+3nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181830(US9145380, 33)
Affinity DataIC50:  1.10E+3nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181831(US9145380, 34)
Affinity DataIC50:  120nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181832(US9145380, 35)
Affinity DataIC50:  170nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181833(US9145380, 36)
Affinity DataIC50:  57nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181834(US9145380, 37)
Affinity DataIC50:  160nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181835(US9145380, 38)
Affinity DataIC50:  220nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181836(US9145380, 39)
Affinity DataIC50:  1.40E+3nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181837(US9145380, 40)
Affinity DataIC50:  1.20E+3nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181838(US9145380, 41)
Affinity DataIC50:  1.10E+3nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181839(US9145380, 42)
Affinity DataIC50:  1.60E+3nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181840(US9145380, 43)
Affinity DataIC50:  110nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181841(US9145380, 44)
Affinity DataIC50:  750nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181842(US9145380, 45)
Affinity DataIC50:  1.30E+3nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181843(US9145380, 46)
Affinity DataIC50:  1.10E+3nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181844(US9145380, 47)
Affinity DataIC50:  1.60E+3nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181845(US9145380, 48)
Affinity DataIC50:  590nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181846(US9145380, 49)
Affinity DataIC50:  36nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM181847(US9145380, 50)
Affinity DataIC50:  130nMpH: 6.8Assay Description:A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
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