Found 1265 Enz. Inhib. hit(s) with Target = 'Tissue-type plasminogen activator' 
Affinity DataKi: 1.50E+4nM ΔG°: -27.3kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Affinity DataKi: 1.68E+4nM ΔG°: -27.0kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Affinity DataKi: 7.50E+5nM ΔG°: -17.7kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Affinity DataKi: 1.80E+6nM ΔG°: -15.5kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Affinity DataKi: >3.90E+3nM ΔG°: >-30.6kJ/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMpH: 7.8 T: 2°CAssay Description:Enzyme activity assay using human and murine PAI-1.More data for this Ligand-Target Pair
Affinity DataIC50: 1.54E+4nMpH: 7.8 T: 2°CAssay Description:Enzyme activity assay using human and murine PAI-1.More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMpH: 7.8 T: 2°CAssay Description:Enzyme activity assay using human and murine PAI-1.More data for this Ligand-Target Pair
Affinity DataIC50: 12nMpH: 7.8 T: 2°CAssay Description:Enzyme activity assay using human and murine PAI-1.More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMpH: 7.8 T: 2°CAssay Description:Enzyme activity assay using human and murine PAI-1.More data for this Ligand-Target Pair
Affinity DataIC50: 86nMpH: 7.8 T: 2°CAssay Description:Enzyme activity assay using human and murine PAI-1.More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMpH: 7.8 T: 2°CAssay Description:Enzyme activity assay using human and murine PAI-1.More data for this Ligand-Target Pair
Affinity DataIC50: 174nMpH: 7.8 T: 2°CAssay Description:Enzyme activity assay using human and murine PAI-1.More data for this Ligand-Target Pair
Affinity DataIC50: 8nMpH: 7.8 T: 2°CAssay Description:Enzyme activity assay using human and murine PAI-1.More data for this Ligand-Target Pair
Affinity DataIC50: 1.18E+4nMpH: 7.8 T: 2°CAssay Description:Enzyme activity assay using human and murine PAI-1.More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 7.8 T: 2°CAssay Description:Enzyme activity assay using human and murine PAI-1.More data for this Ligand-Target Pair
Affinity DataIC50: 28nMpH: 7.8 T: 2°CAssay Description:Enzyme activity assay using human and murine PAI-1.More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 7.8 T: 2°CAssay Description:Enzyme activity assay using human and murine PAI-1.More data for this Ligand-Target Pair
Affinity DataKi: 4.90E+3nM ΔG°: -30.3kJ/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...More data for this Ligand-Target Pair
Affinity DataKi: 8.70E+3nM ΔG°: -28.9kJ/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:For determination of the inhibition constants (Ki), enzyme inhibition was studied at three different substrate concentrations and seven different con...More data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nM ΔG°: >-25.5kJ/molepH: 8.0 T: 2°CAssay Description:For determination of the inhibition constants (Ki), enzyme inhibition was studied at three different substrate concentrations and seven different con...More data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nM ΔG°: >-25.5kJ/molepH: 8.0 T: 2°CAssay Description:For determination of the inhibition constants (Ki), enzyme inhibition was studied at three different substrate concentrations and seven different con...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nM ΔG°: >-17.1kJ/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nM ΔG°: >-17.1kJ/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nM ΔG°: >-17.1kJ/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...More data for this Ligand-Target Pair
Affinity DataKi: 0.290nMAssay Description:Inhibitory constant of the compound against tissue plasminogen activatorMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibitory activity against Tissue plasminogen activatorMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Compound was tested in vitro for inhibition of tissue plasminogen activatorMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibitory activity against Tissue plasminogen activatorMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibitory activity against Tissue plasminogen activatorMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Inhibition of Human Serine Protease tissue type Plasminogen Activator (t-PA).More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibitory activity against Tissue plasminogen activatorMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:The compound was tested for inhibition of human tissue plasminogen activatorMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Inihibtion of Human Serine Protease tissue type Plasminogen ActivatorMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Inhibitory activity against human tissue-type plasminogen activator expressed as dissociation constantMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Inhibition of tissue-type plasminogen activatorMore data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Compound was tested in vitro for inhibition of tissue plasminogen activatorMore data for this Ligand-Target Pair
Affinity DataKi: 67nMAssay Description:Inhibitory constant of the compound against tissue plasminogen activatorMore data for this Ligand-Target Pair
Affinity DataKi: 94nMAssay Description:Inihibtion of Human Serine Protease tissue type Plasminogen ActivatorMore data for this Ligand-Target Pair
Affinity DataKi: 96nMAssay Description:Inhibitory constant of the compound against tissue plasminogen activatorMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibitory constant of the compound against tissue plasminogen activatorMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:The compound was tested for inhibition of human plasminMore data for this Ligand-Target Pair
Affinity DataKi: 106nMAssay Description:Compound was evaluated for the inhibition of Tissue type plasminogen activator (tissue plasminogen activator)More data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:The compound was tested for inhibition of human plasminMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Inhibitory constant of the compound against tissue plasminogen activatorMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Inihibtion of Human Serine Protease tissue type Plasminogen ActivatorMore data for this Ligand-Target Pair
Affinity DataKi: 113nMAssay Description:Inhibition of human t-PAMore data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Compound was tested for its binding affinity against the enzyme Tissue plasminogen activatorMore data for this Ligand-Target Pair
