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Compile Data Set for Download or QSAR

Found 89 hits Enz. Inhib. hit(s) with Target = 'Alcohol dehydrogenase class-3'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM50465807
PNG
(CHEMBL4291042)
Show SMILES CCc1cc(ccc1-c1ccc(cc1)-c1nnn[nH]1)-n1ccnc1
Show InChI InChI=1S/C18H16N6/c1-2-13-11-16(24-10-9-19-12-24)7-8-17(13)14-3-5-15(6-4-14)18-20-22-23-21-18/h3-12H,2H2,1H3,(H,20,21,22,23)
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n/an/a 6.10n/an/an/an/an/an/a



Glenmark Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis


Bioorg Med Chem Lett 28: 3766-3773 (2018)


Article DOI: 10.1016/j.bmcl.2018.10.012
BindingDB Entry DOI: 10.7270/Q21G0PZK
More data for this
Ligand-Target Pair
Alcohol dehydrogenase class-3


(Mus musculus)
BDBM50465805
PNG
(CHEMBL4290485)
Show SMILES Clc1cc(ccc1-c1ccc(cc1)-n1ccnc1)-c1nnn[nH]1
Show InChI InChI=1S/C16H11ClN6/c17-15-9-12(16-19-21-22-20-16)3-6-14(15)11-1-4-13(5-2-11)23-8-7-18-10-23/h1-10H,(H,19,20,21,22)
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n/an/a 7.10n/an/an/an/an/an/a



Glenmark Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Inhibition of mouse GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis


Bioorg Med Chem Lett 28: 3766-3773 (2018)


Article DOI: 10.1016/j.bmcl.2018.10.012
BindingDB Entry DOI: 10.7270/Q21G0PZK
More data for this
Ligand-Target Pair
Alcohol dehydrogenase class-3


(Rattus norvegicus)
BDBM50465805
PNG
(CHEMBL4290485)
Show SMILES Clc1cc(ccc1-c1ccc(cc1)-n1ccnc1)-c1nnn[nH]1
Show InChI InChI=1S/C16H11ClN6/c17-15-9-12(16-19-21-22-20-16)3-6-14(15)11-1-4-13(5-2-11)23-8-7-18-10-23/h1-10H,(H,19,20,21,22)
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n/an/a 9.10n/an/an/an/an/an/a



Glenmark Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Inhibition of rat GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis


Bioorg Med Chem Lett 28: 3766-3773 (2018)


Article DOI: 10.1016/j.bmcl.2018.10.012
BindingDB Entry DOI: 10.7270/Q21G0PZK
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM50465805
PNG
(CHEMBL4290485)
Show SMILES Clc1cc(ccc1-c1ccc(cc1)-n1ccnc1)-c1nnn[nH]1
Show InChI InChI=1S/C16H11ClN6/c17-15-9-12(16-19-21-22-20-16)3-6-14(15)11-1-4-13(5-2-11)23-8-7-18-10-23/h1-10H,(H,19,20,21,22)
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n/an/a 9.20n/an/an/an/an/an/a



Glenmark Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis


Bioorg Med Chem Lett 28: 3766-3773 (2018)


Article DOI: 10.1016/j.bmcl.2018.10.012
BindingDB Entry DOI: 10.7270/Q21G0PZK
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM140260
PNG
(US8906933, (S)-4-(3-ethoxy-4-hydroxy-5-nitrophenyl...)
Show SMILES CCOc1cc(cc(c1O)[N+]([O-])=O)[C@@H]1NC(=O)NC(=C1c1ccccc1)c1ccccc1
Show InChI InChI=1S/C24H21N3O5/c1-2-32-19-14-17(13-18(23(19)28)27(30)31)22-20(15-9-5-3-6-10-15)21(25-24(29)26-22)16-11-7-4-8-12-16/h3-14,22,28H,2H2,1H3,(H2,25,26,29)/t22-/m0/s1
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US Patent
n/an/a 11n/an/an/an/a7.422



N30 Pharmaceuticals, Inc.

US Patent


Assay Description
Receptor binding assays were performed using crude membranes prepared from CHO cells expressing human NK3 receptor. Osanetant (SR142801), a non-pepti...


US Patent US8906933 (2014)


BindingDB Entry DOI: 10.7270/Q2765D15
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM50465829
PNG
(CHEMBL4289979)
Show SMILES CCc1cc(ccc1-c1ccc(cc1F)-c1nnn[nH]1)-n1ccnc1
Show InChI InChI=1S/C18H15FN6/c1-2-12-9-14(25-8-7-20-11-25)4-6-15(12)16-5-3-13(10-17(16)19)18-21-23-24-22-18/h3-11H,2H2,1H3,(H,21,22,23,24)
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n/an/a 11n/an/an/an/an/an/a



Glenmark Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis


Bioorg Med Chem Lett 28: 3766-3773 (2018)


Article DOI: 10.1016/j.bmcl.2018.10.012
BindingDB Entry DOI: 10.7270/Q21G0PZK
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM123711
PNG
(US8741915, 2)
Show SMILES CCOc1cc(cc(c1O)[N+]([O-])=O)[C@@H]1NC(=O)N=C(C1c1ccccc1)c1ccccc1
Show InChI InChI=1S/C24H21N3O5/c1-2-32-19-14-17(13-18(23(19)28)27(30)31)22-20(15-9-5-3-6-10-15)21(25-24(29)26-22)16-11-7-4-8-12-16/h3-14,20,22,28H,2H2,1H3,(H,26,29)/t20?,22-/m0/s1
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n/an/a 11n/an/an/an/a7.425



N30 Pharmaceuticals, Inc.

US Patent


Assay Description
GSNO and Enzyme/NADH Solutions are made up fresh each day. The Solutions are filtered and allowed to warm to room temperature. GSNO Solution: 100 mM ...


US Patent US8741915 (2014)


BindingDB Entry DOI: 10.7270/Q2X34W5J
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM50465828
PNG
(CHEMBL4294439)
Show SMILES Cc1cc(ccc1-c1ccc(cc1Cl)-c1nnn[nH]1)-n1ccnc1
Show InChI InChI=1S/C17H13ClN6/c1-11-8-13(24-7-6-19-10-24)3-5-14(11)15-4-2-12(9-16(15)18)17-20-22-23-21-17/h2-10H,1H3,(H,20,21,22,23)
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n/an/a 12n/an/an/an/an/an/a



Glenmark Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis


Bioorg Med Chem Lett 28: 3766-3773 (2018)


Article DOI: 10.1016/j.bmcl.2018.10.012
BindingDB Entry DOI: 10.7270/Q21G0PZK
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM123704
PNG
(US8741915, 146)
Show SMILES CCOc1cc(cc(C(O)=O)c1O)[C@@H]1NC(=O)N=C(C1c1ccsc1)c1cnn(C)c1
Show InChI InChI=1S/C21H20N4O5S/c1-3-30-15-7-12(6-14(19(15)26)20(27)28)17-16(11-4-5-31-10-11)18(24-21(29)23-17)13-8-22-25(2)9-13/h4-10,16-17,26H,3H2,1-2H3,(H,23,29)(H,27,28)/t16?,17-/m0/s1
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n/an/a 13n/an/an/an/a7.425



N30 Pharmaceuticals, Inc.

US Patent


Assay Description
GSNO and Enzyme/NADH Solutions are made up fresh each day. The Solutions are filtered and allowed to warm to room temperature. GSNO Solution: 100 mM ...


US Patent US8741915 (2014)


BindingDB Entry DOI: 10.7270/Q2X34W5J
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM47039
PNG
(US8906933, (R)-3-ethoxy-2-hydroxy-5-(6-(1-methyl-1...)
Show SMILES CCOc1cc(cc(C(O)=O)c1O)C1NC(=O)NC(C1c1ccsc1)c1cnn(C)c1
Show InChI InChI=1S/C21H22N4O5S/c1-3-30-15-7-12(6-14(19(15)26)20(27)28)17-16(11-4-5-31-10-11)18(24-21(29)23-17)13-8-22-25(2)9-13/h4-10,16-18,26H,3H2,1-2H3,(H,27,28)(H2,23,24,29)
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n/an/a 13n/an/an/an/a7.422



N30 Pharmaceuticals, Inc.

US Patent


Assay Description
Receptor binding assays were performed using crude membranes prepared from CHO cells expressing human NK3 receptor. Osanetant (SR142801), a non-pepti...


US Patent US8906933 (2014)


BindingDB Entry DOI: 10.7270/Q2765D15
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM50465806
PNG
(CHEMBL4289333)
Show SMILES Cc1cc(cnc1-c1ccc(cc1F)-c1nnn[nH]1)-n1ccnc1
Show InChI InChI=1S/C16H12FN7/c1-10-6-12(24-5-4-18-9-24)8-19-15(10)13-3-2-11(7-14(13)17)16-20-22-23-21-16/h2-9H,1H3,(H,20,21,22,23)
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n/an/a 14n/an/an/an/an/an/a



Glenmark Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis


Bioorg Med Chem Lett 28: 3766-3773 (2018)


Article DOI: 10.1016/j.bmcl.2018.10.012
BindingDB Entry DOI: 10.7270/Q21G0PZK
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM50465826
PNG
(CHEMBL4283184)
Show SMILES Cc1cc(ccc1-c1ccc(cc1)-c1nnn[nH]1)-n1ccnc1
Show InChI InChI=1S/C17H14N6/c1-12-10-15(23-9-8-18-11-23)6-7-16(12)13-2-4-14(5-3-13)17-19-21-22-20-17/h2-11H,1H3,(H,19,20,21,22)
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n/an/a 14n/an/an/an/an/an/a



Glenmark Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis


Bioorg Med Chem Lett 28: 3766-3773 (2018)


Article DOI: 10.1016/j.bmcl.2018.10.012
BindingDB Entry DOI: 10.7270/Q21G0PZK
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM123702
PNG
(US8741915, 143 | US8741915, 144)
Show SMILES CCOc1cc(cc(c1O)N(=O)=O)C1=NC(=O)NC(C1c1ccsc1)c1cccnc1
Show InChI InChI=1S/C21H18N4O5S/c1-2-30-16-9-14(8-15(20(16)26)25(28)29)19-17(13-5-7-31-11-13)18(23-21(27)24-19)12-4-3-6-22-10-12/h3-11,17-18,26H,2H2,1H3,(H,23,27)
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n/an/a 16n/an/an/an/a7.425



N30 Pharmaceuticals, Inc.

US Patent


Assay Description
GSNO and Enzyme/NADH Solutions are made up fresh each day. The Solutions are filtered and allowed to warm to room temperature. GSNO Solution: 100 mM ...


US Patent US8741915 (2014)


BindingDB Entry DOI: 10.7270/Q2X34W5J
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM47037
PNG
(US8906933, (S)-4-(3-ethoxy-4-hydroxy-5-nitrophenyl...)
Show SMILES CCOc1cc(cc(c1O)[N+]([O-])=O)[C@@H]1NC(=O)NC(=C1c1ccsc1)c1cccnc1
Show InChI InChI=1S/C21H18N4O5S/c1-2-30-16-9-14(8-15(20(16)26)25(28)29)19-17(13-5-7-31-11-13)18(23-21(27)24-19)12-4-3-6-22-10-12/h3-11,19,26H,2H2,1H3,(H2,23,24,27)/t19-/m0/s1
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n/an/a 16n/an/an/an/a7.422



N30 Pharmaceuticals, Inc.

US Patent


Assay Description
Receptor binding assays were performed using crude membranes prepared from CHO cells expressing human NK3 receptor. Osanetant (SR142801), a non-pepti...


US Patent US8906933 (2014)


BindingDB Entry DOI: 10.7270/Q2765D15
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM50465837
PNG
(CHEMBL4286132)
Show SMILES Cc1cc(cnc1-c1ccc(cc1)-c1nnn[nH]1)-n1ccnc1
Show InChI InChI=1S/C16H13N7/c1-11-8-14(23-7-6-17-10-23)9-18-15(11)12-2-4-13(5-3-12)16-19-21-22-20-16/h2-10H,1H3,(H,19,20,21,22)
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n/an/a 17n/an/an/an/an/an/a



Glenmark Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis


Bioorg Med Chem Lett 28: 3766-3773 (2018)


Article DOI: 10.1016/j.bmcl.2018.10.012
BindingDB Entry DOI: 10.7270/Q21G0PZK
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM140262
PNG
(US8906933, (S)-4-(3-ethoxy-4-hydroxy-5-nitrophenyl...)
Show SMILES CCOc1cc(cc(c1O)[N+]([O-])=O)[C@@H]1NC(=O)NC(=C1c1ccsc1)c1ccccc1
Show InChI InChI=1S/C22H19N3O5S/c1-2-30-17-11-15(10-16(21(17)26)25(28)29)20-18(14-8-9-31-12-14)19(23-22(27)24-20)13-6-4-3-5-7-13/h3-12,20,26H,2H2,1H3,(H2,23,24,27)/t20-/m0/s1
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n/an/a 18n/an/an/an/a7.422



N30 Pharmaceuticals, Inc.

US Patent


Assay Description
Receptor binding assays were performed using crude membranes prepared from CHO cells expressing human NK3 receptor. Osanetant (SR142801), a non-pepti...


US Patent US8906933 (2014)


BindingDB Entry DOI: 10.7270/Q2765D15
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM123712
PNG
(US8741915, 6)
Show SMILES CCOc1cc(cc(c1O)[N+]([O-])=O)[C@@H]1NC(=O)N=C(C1c1ccsc1)c1ccccc1
Show InChI InChI=1S/C22H19N3O5S/c1-2-30-17-11-15(10-16(21(17)26)25(28)29)20-18(14-8-9-31-12-14)19(23-22(27)24-20)13-6-4-3-5-7-13/h3-12,18,20,26H,2H2,1H3,(H,24,27)/t18?,20-/m0/s1
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n/an/a 18n/an/an/an/a7.425



N30 Pharmaceuticals, Inc.

US Patent


Assay Description
GSNO and Enzyme/NADH Solutions are made up fresh each day. The Solutions are filtered and allowed to warm to room temperature. GSNO Solution: 100 mM ...


US Patent US8741915 (2014)


BindingDB Entry DOI: 10.7270/Q2X34W5J
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM46437
PNG
(US8906933, 4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-6-...)
Show SMILES CCOc1cc(cc(c1O)[N+]([O-])=O)C1NC(=O)NC(=C1c1ccsc1)c1ccccc1
Show InChI InChI=1S/C22H19N3O5S/c1-2-30-17-11-15(10-16(21(17)26)25(28)29)20-18(14-8-9-31-12-14)19(23-22(27)24-20)13-6-4-3-5-7-13/h3-12,20,26H,2H2,1H3,(H2,23,24,27)
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n/an/a 19n/an/an/an/a7.422



N30 Pharmaceuticals, Inc.

US Patent


Assay Description
Receptor binding assays were performed using crude membranes prepared from CHO cells expressing human NK3 receptor. Osanetant (SR142801), a non-pepti...


US Patent US8906933 (2014)


BindingDB Entry DOI: 10.7270/Q2765D15
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM123694
PNG
(US8741915, 5)
Show SMILES CCOc1cc(cc(c1O)N(=O)=O)C1NC(=O)N=C(C1c1ccsc1)c1ccccc1
Show InChI InChI=1S/C22H19N3O5S/c1-2-30-17-11-15(10-16(21(17)26)25(28)29)20-18(14-8-9-31-12-14)19(23-22(27)24-20)13-6-4-3-5-7-13/h3-12,18,20,26H,2H2,1H3,(H,24,27)
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n/an/a 19n/an/an/an/a7.425



N30 Pharmaceuticals, Inc.

US Patent


Assay Description
GSNO and Enzyme/NADH Solutions are made up fresh each day. The Solutions are filtered and allowed to warm to room temperature. GSNO Solution: 100 mM ...


US Patent US8741915 (2014)


BindingDB Entry DOI: 10.7270/Q2X34W5J
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM50354475
PNG
(CHEMBL1738699)
Show SMILES Cc1cc(ccc1-n1c(CCC(O)=O)ccc1-c1ccc(cc1)-n1ccnc1)C(N)=O
Show InChI InChI=1S/C24H22N4O3/c1-16-14-18(24(25)31)4-9-21(16)28-20(8-11-23(29)30)7-10-22(28)17-2-5-19(6-3-17)27-13-12-26-15-27/h2-7,9-10,12-15H,8,11H2,1H3,(H2,25,31)(H,29,30)
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Glenmark Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis


Bioorg Med Chem Lett 28: 3766-3773 (2018)


Article DOI: 10.1016/j.bmcl.2018.10.012
BindingDB Entry DOI: 10.7270/Q21G0PZK
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM50465814
PNG
(CHEMBL4283157)
Show SMILES Cc1cc(ccc1-c1ccc(cc1)C(O)=O)-n1ccnc1
Show InChI InChI=1S/C17H14N2O2/c1-12-10-15(19-9-8-18-11-19)6-7-16(12)13-2-4-14(5-3-13)17(20)21/h2-11H,1H3,(H,20,21)
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n/an/a 20n/an/an/an/an/an/a



Glenmark Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis


Bioorg Med Chem Lett 28: 3766-3773 (2018)


Article DOI: 10.1016/j.bmcl.2018.10.012
BindingDB Entry DOI: 10.7270/Q21G0PZK
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM50465810
PNG
(CHEMBL4278220)
Show SMILES Clc1cc(cnc1-c1ccc(cc1)-c1nnn[nH]1)-n1ccnc1
Show InChI InChI=1S/C15H10ClN7/c16-13-7-12(23-6-5-17-9-23)8-18-14(13)10-1-3-11(4-2-10)15-19-21-22-20-15/h1-9H,(H,19,20,21,22)
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n/an/a 20n/an/an/an/an/an/a



Glenmark Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis


Bioorg Med Chem Lett 28: 3766-3773 (2018)


Article DOI: 10.1016/j.bmcl.2018.10.012
BindingDB Entry DOI: 10.7270/Q21G0PZK
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM50465813
PNG
(CHEMBL4287066)
Show SMILES Fc1cc(ccc1-c1ccc(cc1)-n1ccnc1)-c1nnn[nH]1
Show InChI InChI=1S/C16H11FN6/c17-15-9-12(16-19-21-22-20-16)3-6-14(15)11-1-4-13(5-2-11)23-8-7-18-10-23/h1-10H,(H,19,20,21,22)
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n/an/a 20n/an/an/an/an/an/a



Glenmark Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis


Bioorg Med Chem Lett 28: 3766-3773 (2018)


Article DOI: 10.1016/j.bmcl.2018.10.012
BindingDB Entry DOI: 10.7270/Q21G0PZK
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM50465811
PNG
(CHEMBL4290516)
Show SMILES c1cn(cn1)-c1ccc(cc1)-c1ccc(cc1)-c1nn[nH]n1
Show InChI InChI=1S/C16H12N6/c1-3-14(16-18-20-21-19-16)4-2-12(1)13-5-7-15(8-6-13)22-10-9-17-11-22/h1-11H,(H,18,19,20,21)
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n/an/a 22n/an/an/an/an/an/a



Glenmark Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis


Bioorg Med Chem Lett 28: 3766-3773 (2018)


Article DOI: 10.1016/j.bmcl.2018.10.012
BindingDB Entry DOI: 10.7270/Q21G0PZK
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM50465840
PNG
(CHEMBL4277254)
Show SMILES Clc1cc(ccc1-c1ccc(cc1)-c1nnn[nH]1)-n1ccnc1
Show InChI InChI=1S/C16H11ClN6/c17-15-9-13(23-8-7-18-10-23)5-6-14(15)11-1-3-12(4-2-11)16-19-21-22-20-16/h1-10H,(H,19,20,21,22)
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n/an/a 22n/an/an/an/an/an/a



Glenmark Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis


Bioorg Med Chem Lett 28: 3766-3773 (2018)


Article DOI: 10.1016/j.bmcl.2018.10.012
BindingDB Entry DOI: 10.7270/Q21G0PZK
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM123710
PNG
(US8741915, 169)
Show SMILES Cn1cc(cn1)C1=NC(=O)N[C@H](C1c1ccsc1)c1ccc(C(O)=O)c(O)c1
Show InChI InChI=1S/C19H16N4O4S/c1-23-8-12(7-20-23)17-15(11-4-5-28-9-11)16(21-19(27)22-17)10-2-3-13(18(25)26)14(24)6-10/h2-9,15-16,24H,1H3,(H,21,27)(H,25,26)/t15?,16-/m0/s1
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n/an/a 23n/an/an/an/a7.425



N30 Pharmaceuticals, Inc.

US Patent


Assay Description
GSNO and Enzyme/NADH Solutions are made up fresh each day. The Solutions are filtered and allowed to warm to room temperature. GSNO Solution: 100 mM ...


US Patent US8741915 (2014)


BindingDB Entry DOI: 10.7270/Q2X34W5J
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM47045
PNG
(US8906933, (R)-2-hydroxy-4-(6-(1-methyl-1H-pyrazol...)
Show SMILES Cn1cc(cn1)C1NC(=O)NC(C1c1ccsc1)c1ccc(C(O)=O)c(O)c1
Show InChI InChI=1S/C19H18N4O4S/c1-23-8-12(7-20-23)17-15(11-4-5-28-9-11)16(21-19(27)22-17)10-2-3-13(18(25)26)14(24)6-10/h2-9,15-17,24H,1H3,(H,25,26)(H2,21,22,27)
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n/an/a 23n/an/an/an/a7.422



N30 Pharmaceuticals, Inc.

US Patent


Assay Description
Receptor binding assays were performed using crude membranes prepared from CHO cells expressing human NK3 receptor. Osanetant (SR142801), a non-pepti...


US Patent US8906933 (2014)


BindingDB Entry DOI: 10.7270/Q2765D15
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM123696
PNG
(US8741915, 116)
Show SMILES CCOc1cc(cc(c1O)N(=O)=O)C1NC(=O)N=C(C1c1ccsc1)c1cccnc1
Show InChI InChI=1S/C21H18N4O5S/c1-2-30-16-9-14(8-15(20(16)26)25(28)29)19-17(13-5-7-31-11-13)18(23-21(27)24-19)12-4-3-6-22-10-12/h3-11,17,19,26H,2H2,1H3,(H,24,27)
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n/an/a 24n/an/an/an/a7.425



N30 Pharmaceuticals, Inc.

US Patent


Assay Description
GSNO and Enzyme/NADH Solutions are made up fresh each day. The Solutions are filtered and allowed to warm to room temperature. GSNO Solution: 100 mM ...


US Patent US8741915 (2014)


BindingDB Entry DOI: 10.7270/Q2X34W5J
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM50465827
PNG
(CHEMBL4286551)
Show SMILES CCc1cc(ccc1-c1ccc(cc1)-c1nnn[nH]1)-n1ccnc1C
Show InChI InChI=1S/C19H18N6/c1-3-14-12-17(25-11-10-20-13(25)2)8-9-18(14)15-4-6-16(7-5-15)19-21-23-24-22-19/h4-12H,3H2,1-2H3,(H,21,22,23,24)
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Glenmark Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis


Bioorg Med Chem Lett 28: 3766-3773 (2018)


Article DOI: 10.1016/j.bmcl.2018.10.012
BindingDB Entry DOI: 10.7270/Q21G0PZK
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM47036
PNG
(US8906933, 4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-6-...)
Show SMILES CCOc1cc(cc(c1O)[N+]([O-])=O)C1NC(=O)NC(=C1c1ccsc1)c1cccnc1
Show InChI InChI=1S/C21H18N4O5S/c1-2-30-16-9-14(8-15(20(16)26)25(28)29)19-17(13-5-7-31-11-13)18(23-21(27)24-19)12-4-3-6-22-10-12/h3-11,19,26H,2H2,1H3,(H2,23,24,27)
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n/an/a 24n/an/an/an/a7.422



N30 Pharmaceuticals, Inc.

US Patent


Assay Description
Receptor binding assays were performed using crude membranes prepared from CHO cells expressing human NK3 receptor. Osanetant (SR142801), a non-pepti...


US Patent US8906933 (2014)


BindingDB Entry DOI: 10.7270/Q2765D15
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM50465822
PNG
(CHEMBL4279145)
Show SMILES Cc1cc(ccc1-c1ccc(cc1)-n1ccnc1)-c1nnn[nH]1
Show InChI InChI=1S/C17H14N6/c1-12-10-14(17-19-21-22-20-17)4-7-16(12)13-2-5-15(6-3-13)23-9-8-18-11-23/h2-11H,1H3,(H,19,20,21,22)
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n/an/a 26n/an/an/an/an/an/a



Glenmark Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis


Bioorg Med Chem Lett 28: 3766-3773 (2018)


Article DOI: 10.1016/j.bmcl.2018.10.012
BindingDB Entry DOI: 10.7270/Q21G0PZK
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM47039
PNG
(US8906933, (R)-3-ethoxy-2-hydroxy-5-(6-(1-methyl-1...)
Show SMILES CCOc1cc(cc(C(O)=O)c1O)C1NC(=O)NC(C1c1ccsc1)c1cnn(C)c1
Show InChI InChI=1S/C21H22N4O5S/c1-3-30-15-7-12(6-14(19(15)26)20(27)28)17-16(11-4-5-31-10-11)18(24-21(29)23-17)13-8-22-25(2)9-13/h4-10,16-18,26H,3H2,1-2H3,(H,27,28)(H2,23,24,29)
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n/an/a 27n/an/an/an/a7.422



N30 Pharmaceuticals, Inc.

US Patent


Assay Description
Receptor binding assays were performed using crude membranes prepared from CHO cells expressing human NK3 receptor. Osanetant (SR142801), a non-pepti...


US Patent US8906933 (2014)


BindingDB Entry DOI: 10.7270/Q2765D15
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM50465830
PNG
(CHEMBL4281451)
Show SMILES Fc1cc(ccc1-c1ncc(cc1Cl)-n1ccnc1)-c1nnn[nH]1
Show InChI InChI=1S/C15H9ClFN7/c16-12-6-10(24-4-3-18-8-24)7-19-14(12)11-2-1-9(5-13(11)17)15-20-22-23-21-15/h1-8H,(H,20,21,22,23)
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n/an/a 27n/an/an/an/an/an/a



Glenmark Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis


Bioorg Med Chem Lett 28: 3766-3773 (2018)


Article DOI: 10.1016/j.bmcl.2018.10.012
BindingDB Entry DOI: 10.7270/Q21G0PZK
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM123701
PNG
(US8741915, 142)
Show SMILES CCOc1cc(cc(C(O)=O)c1O)C1NC(=O)N=C(C1c1ccsc1)c1cnn(C)c1
Show InChI InChI=1S/C21H20N4O5S/c1-3-30-15-7-12(6-14(19(15)26)20(27)28)17-16(11-4-5-31-10-11)18(24-21(29)23-17)13-8-22-25(2)9-13/h4-10,16-17,26H,3H2,1-2H3,(H,23,29)(H,27,28)
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n/an/a 27n/an/an/an/a7.425



N30 Pharmaceuticals, Inc.

US Patent


Assay Description
GSNO and Enzyme/NADH Solutions are made up fresh each day. The Solutions are filtered and allowed to warm to room temperature. GSNO Solution: 100 mM ...


US Patent US8741915 (2014)


BindingDB Entry DOI: 10.7270/Q2X34W5J
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM140264
PNG
(US8906933, (S)-4-(3-ethoxy-4-hydroxy-5-nitrophenyl...)
Show SMILES CCOc1cc(cc(c1O)[N+]([O-])=O)[C@@H]1NC(=O)NC(=C1c1ccccc1)c1cccnc1
Show InChI InChI=1S/C23H20N4O5/c1-2-32-18-12-16(11-17(22(18)28)27(30)31)21-19(14-7-4-3-5-8-14)20(25-23(29)26-21)15-9-6-10-24-13-15/h3-13,21,28H,2H2,1H3,(H2,25,26,29)/t21-/m0/s1
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n/an/a 28n/an/an/an/a7.422



N30 Pharmaceuticals, Inc.

US Patent


Assay Description
Receptor binding assays were performed using crude membranes prepared from CHO cells expressing human NK3 receptor. Osanetant (SR142801), a non-pepti...


US Patent US8906933 (2014)


BindingDB Entry DOI: 10.7270/Q2765D15
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM123714
PNG
(US8741915, 67)
Show SMILES CCOc1cc(cc(c1O)[N+]([O-])=O)[C@@H]1NC(=O)N=C(C1c1ccccc1)c1cccnc1
Show InChI InChI=1S/C23H20N4O5/c1-2-32-18-12-16(11-17(22(18)28)27(30)31)21-19(14-7-4-3-5-8-14)20(25-23(29)26-21)15-9-6-10-24-13-15/h3-13,19,21,28H,2H2,1H3,(H,26,29)/t19?,21-/m0/s1
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n/an/a 28n/an/an/an/a7.425



N30 Pharmaceuticals, Inc.

US Patent


Assay Description
GSNO and Enzyme/NADH Solutions are made up fresh each day. The Solutions are filtered and allowed to warm to room temperature. GSNO Solution: 100 mM ...


US Patent US8741915 (2014)


BindingDB Entry DOI: 10.7270/Q2X34W5J
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM123693
PNG
(US8741915, 1)
Show SMILES CCOc1cc(cc(c1O)N(=O)=O)C1NC(=O)N=C(C1c1ccccc1)c1ccccc1
Show InChI InChI=1S/C24H21N3O5/c1-2-32-19-14-17(13-18(23(19)28)27(30)31)22-20(15-9-5-3-6-10-15)21(25-24(29)26-22)16-11-7-4-8-12-16/h3-14,20,22,28H,2H2,1H3,(H,26,29)
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n/an/a 29n/an/an/an/a7.425



N30 Pharmaceuticals, Inc.

US Patent


Assay Description
GSNO and Enzyme/NADH Solutions are made up fresh each day. The Solutions are filtered and allowed to warm to room temperature. GSNO Solution: 100 mM ...


US Patent US8741915 (2014)


BindingDB Entry DOI: 10.7270/Q2X34W5J
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM46287
PNG
(US8906933, 4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-5,...)
Show SMILES CCOc1cc(cc(c1O)[N+]([O-])=O)C1NC(=O)NC(=C1c1ccccc1)c1ccccc1
Show InChI InChI=1S/C24H21N3O5/c1-2-32-19-14-17(13-18(23(19)28)27(30)31)22-20(15-9-5-3-6-10-15)21(25-24(29)26-22)16-11-7-4-8-12-16/h3-14,22,28H,2H2,1H3,(H2,25,26,29)
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n/an/a 29n/an/an/an/a7.422



N30 Pharmaceuticals, Inc.

US Patent


Assay Description
Receptor binding assays were performed using crude membranes prepared from CHO cells expressing human NK3 receptor. Osanetant (SR142801), a non-pepti...


US Patent US8906933 (2014)


BindingDB Entry DOI: 10.7270/Q2765D15
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM50465820
PNG
(CHEMBL4285078)
Show SMILES Cc1cc(ccc1-c1ccc(cc1)-n1ccnc1)C(O)=O
Show InChI InChI=1S/C17H14N2O2/c1-12-10-14(17(20)21)4-7-16(12)13-2-5-15(6-3-13)19-9-8-18-11-19/h2-11H,1H3,(H,20,21)
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Glenmark Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis


Bioorg Med Chem Lett 28: 3766-3773 (2018)


Article DOI: 10.1016/j.bmcl.2018.10.012
BindingDB Entry DOI: 10.7270/Q21G0PZK
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM50465819
PNG
(CHEMBL4282722)
Show SMILES OC(=O)c1ccc(c(F)c1)-c1ccc(cc1)-n1ccnc1
Show InChI InChI=1S/C16H11FN2O2/c17-15-9-12(16(20)21)3-6-14(15)11-1-4-13(5-2-11)19-8-7-18-10-19/h1-10H,(H,20,21)
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n/an/a 29n/an/an/an/an/an/a



Glenmark Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis


Bioorg Med Chem Lett 28: 3766-3773 (2018)


Article DOI: 10.1016/j.bmcl.2018.10.012
BindingDB Entry DOI: 10.7270/Q21G0PZK
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM50465821
PNG
(CHEMBL4292916)
Show SMILES OC(=O)c1ccc(c(Cl)c1)-c1ccc(cc1)-n1ccnc1
Show InChI InChI=1S/C16H11ClN2O2/c17-15-9-12(16(20)21)3-6-14(15)11-1-4-13(5-2-11)19-8-7-18-10-19/h1-10H,(H,20,21)
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n/an/a 30n/an/an/an/an/an/a



Glenmark Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis


Bioorg Med Chem Lett 28: 3766-3773 (2018)


Article DOI: 10.1016/j.bmcl.2018.10.012
BindingDB Entry DOI: 10.7270/Q21G0PZK
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM50465835
PNG
(CHEMBL4279294)
Show SMILES c1cn(cn1)-c1ccc(nc1)-c1ccc(cc1)-c1nnn[nH]1
Show InChI InChI=1S/C15H11N7/c1-3-12(15-18-20-21-19-15)4-2-11(1)14-6-5-13(9-17-14)22-8-7-16-10-22/h1-10H,(H,18,19,20,21)
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n/an/a 32n/an/an/an/an/an/a



Glenmark Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis


Bioorg Med Chem Lett 28: 3766-3773 (2018)


Article DOI: 10.1016/j.bmcl.2018.10.012
BindingDB Entry DOI: 10.7270/Q21G0PZK
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM123706
PNG
(US8741915, 148)
Show SMILES CCOc1cc(cc(c1O)N(=O)=O)C1=NC(=O)NC(C1c1ccsc1)c1ccn(C)n1
Show InChI InChI=1S/C20H19N5O5S/c1-3-30-15-9-12(8-14(19(15)26)25(28)29)17-16(11-5-7-31-10-11)18(22-20(27)21-17)13-4-6-24(2)23-13/h4-10,16,18,26H,3H2,1-2H3,(H,22,27)
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US Patent
n/an/a 35n/an/an/an/a7.425



N30 Pharmaceuticals, Inc.

US Patent


Assay Description
GSNO and Enzyme/NADH Solutions are made up fresh each day. The Solutions are filtered and allowed to warm to room temperature. GSNO Solution: 100 mM ...


US Patent US8741915 (2014)


BindingDB Entry DOI: 10.7270/Q2X34W5J
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM47043
PNG
(US8906933, (S)-4-(3-ethoxy-4-hydroxy-5-nitrophenyl...)
Show SMILES CCOc1cc(cc(c1O)[N+]([O-])=O)[C@@H]1NC(=O)NC(c2ccn(C)n2)=C1c1ccsc1
Show InChI InChI=1S/C20H19N5O5S/c1-3-30-15-9-12(8-14(19(15)26)25(28)29)17-16(11-5-7-31-10-11)18(22-20(27)21-17)13-4-6-24(2)23-13/h4-10,17,26H,3H2,1-2H3,(H2,21,22,27)/t17-/m0/s1
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n/an/a 35n/an/an/an/a7.422



N30 Pharmaceuticals, Inc.

US Patent


Assay Description
Receptor binding assays were performed using crude membranes prepared from CHO cells expressing human NK3 receptor. Osanetant (SR142801), a non-pepti...


US Patent US8906933 (2014)


BindingDB Entry DOI: 10.7270/Q2765D15
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM50465834
PNG
(CHEMBL4283715)
Show SMILES Cc1cc(cnc1-c1ccc(cc1F)C(O)=O)-n1ccnc1
Show InChI InChI=1S/C16H12FN3O2/c1-10-6-12(20-5-4-18-9-20)8-19-15(10)13-3-2-11(16(21)22)7-14(13)17/h2-9H,1H3,(H,21,22)
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n/an/a 36n/an/an/an/an/an/a



Glenmark Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis


Bioorg Med Chem Lett 28: 3766-3773 (2018)


Article DOI: 10.1016/j.bmcl.2018.10.012
BindingDB Entry DOI: 10.7270/Q21G0PZK
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM50465823
PNG
(CHEMBL4282612)
Show SMILES Cc1nccn1-c1ccc(cc1)-c1ccc(cc1Cl)-c1nnn[nH]1
Show InChI InChI=1S/C17H13ClN6/c1-11-19-8-9-24(11)14-5-2-12(3-6-14)15-7-4-13(10-16(15)18)17-20-22-23-21-17/h2-10H,1H3,(H,20,21,22,23)
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n/an/a 37n/an/an/an/an/an/a



Glenmark Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis


Bioorg Med Chem Lett 28: 3766-3773 (2018)


Article DOI: 10.1016/j.bmcl.2018.10.012
BindingDB Entry DOI: 10.7270/Q21G0PZK
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM50465841
PNG
(CHEMBL4281650)
Show SMILES OC(=O)c1ccc(-c2ccc(cc2)-n2ccnc2)c(c1)C(F)(F)F
Show InChI InChI=1S/C17H11F3N2O2/c18-17(19,20)15-9-12(16(23)24)3-6-14(15)11-1-4-13(5-2-11)22-8-7-21-10-22/h1-10H,(H,23,24)
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n/an/a 38n/an/an/an/an/an/a



Glenmark Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis


Bioorg Med Chem Lett 28: 3766-3773 (2018)


Article DOI: 10.1016/j.bmcl.2018.10.012
BindingDB Entry DOI: 10.7270/Q21G0PZK
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM50465824
PNG
(CHEMBL4285208)
Show SMILES FC(F)(F)c1cc(ccc1-c1ccc(cc1)-n1ccnc1)-c1nnn[nH]1
Show InChI InChI=1S/C17H11F3N6/c18-17(19,20)15-9-12(16-22-24-25-23-16)3-6-14(15)11-1-4-13(5-2-11)26-8-7-21-10-26/h1-10H,(H,22,23,24,25)
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n/an/a 39n/an/an/an/an/an/a



Glenmark Pharmaceuticals Limited

Curated by ChEMBL


Assay Description
Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis


Bioorg Med Chem Lett 28: 3766-3773 (2018)


Article DOI: 10.1016/j.bmcl.2018.10.012
BindingDB Entry DOI: 10.7270/Q21G0PZK
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM47045
PNG
(US8906933, (R)-2-hydroxy-4-(6-(1-methyl-1H-pyrazol...)
Show SMILES Cn1cc(cn1)C1NC(=O)NC(C1c1ccsc1)c1ccc(C(O)=O)c(O)c1
Show InChI InChI=1S/C19H18N4O4S/c1-23-8-12(7-20-23)17-15(11-4-5-28-9-11)16(21-19(27)22-17)10-2-3-13(18(25)26)14(24)6-10/h2-9,15-17,24H,1H3,(H,25,26)(H2,21,22,27)
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US Patent
n/an/a 39n/an/an/an/a7.422



N30 Pharmaceuticals, Inc.

US Patent


Assay Description
Receptor binding assays were performed using crude membranes prepared from CHO cells expressing human NK3 receptor. Osanetant (SR142801), a non-pepti...


US Patent US8906933 (2014)


BindingDB Entry DOI: 10.7270/Q2765D15
More data for this
Ligand-Target Pair
S-nitrosoglutathione reductase (GSNOR)


(Homo sapiens (Human))
BDBM123708
PNG
(US8741915, 159)
Show SMILES Cn1ccc(n1)C1=NC(=O)NC(C1c1ccsc1)c1ccc(C(O)=O)c(O)c1
Show InChI InChI=1S/C19H16N4O4S/c1-23-6-4-13(22-23)17-15(11-5-7-28-9-11)16(20-19(27)21-17)10-2-3-12(18(25)26)14(24)8-10/h2-9,15-16,24H,1H3,(H,20,27)(H,25,26)
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n/an/a 39n/an/an/an/a7.425



N30 Pharmaceuticals, Inc.

US Patent


Assay Description
GSNO and Enzyme/NADH Solutions are made up fresh each day. The Solutions are filtered and allowed to warm to room temperature. GSNO Solution: 100 mM ...


US Patent US8741915 (2014)


BindingDB Entry DOI: 10.7270/Q2X34W5J
More data for this
Ligand-Target Pair
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