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Compile Data Set for Download or QSAR

Found 165 hits Enz. Inhib. hit(s) with Target = 'Arachidonate 15-lipoxygenase, type II'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50516347
PNG
(CHEMBL4531593)
Show SMILES Cc1nc2cc(C)c(CN(C#C)c3ccc(C(=O)N[C@@H](CCc4nnnn4CC(O)=O)C(O)=O)c(F)c3)cc2c(=O)[nH]1
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n/an/a 2.40n/an/an/an/an/an/a



Henan University of Chinese Medicine

Curated by ChEMBL


Assay Description
Inhibition of thymidylate synthase (unknown origin)


Eur J Med Chem 178: 341-351 (2019)


Article DOI: 10.1016/j.ejmech.2019.05.071
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50235696
PNG
(CHEMBL4060383)
Show SMILES Nc1nc(N)c2c(n1)[nH]c1cccc(Sc3ccc4ccccc4c3)c21
Show InChI InChI=1S/C20H15N5S/c21-18-17-16-14(23-19(17)25-20(22)24-18)6-3-7-15(16)26-13-9-8-11-4-1-2-5-12(11)10-13/h1-10H,(H5,21,22,23,24,25)
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n/an/a 120n/an/an/an/an/an/a



Duquesne University

Curated by ChEMBL


Assay Description
Inhibition of human thymidylate synthase using dUMP/(6R,S)-tetrahydrofolate as substrate/co-factor by spectrophotometric method


Bioorg Med Chem Lett 27: 1602-1607 (2017)


Article DOI: 10.1016/j.bmcl.2017.02.018
BindingDB Entry DOI: 10.7270/Q2P55QR0
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50528941
PNG
(CHEMBL4470361)
Show SMILES Nc1nc2[nH]cc(Cc3ccc(cc3)C(=O)Nc3cccc(c3)C(O)=O)c2c(=O)[nH]1
Show InChI InChI=1S/C21H17N5O4/c22-21-25-17-16(19(28)26-21)14(10-23-17)8-11-4-6-12(7-5-11)18(27)24-15-3-1-2-13(9-15)20(29)30/h1-7,9-10H,8H2,(H,24,27)(H,29,30)(H4,22,23,25,26,28)
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n/an/a 130n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometry


Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111673
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50512138
PNG
(CHEMBL4550585)
Show SMILES Clc1ccc(cc1)-n1cc(nn1)-c1ccccc1NS(=O)(=O)c1c[nH]c(=O)[nH]c1=O
Show InChI InChI=1S/C18H13ClN6O4S/c19-11-5-7-12(8-6-11)25-10-15(22-24-25)13-3-1-2-4-14(13)23-30(28,29)16-9-20-18(27)21-17(16)26/h1-10,23H,(H2,20,21,26,27)
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n/an/a 130n/an/an/an/an/an/a



China Medical University

Curated by ChEMBL


Assay Description
Inhibition of human thymidylate synthase using dUMP as substrate by spectrophotometric method


Eur J Med Chem 171: 282-296 (2019)


Article DOI: 10.1016/j.ejmech.2019.03.047
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50235700
PNG
(CHEMBL4096329)
Show SMILES COc1ccc(Sc2cccc3[nH]c4nc(N)nc(N)c4c23)cc1
Show InChI InChI=1S/C17H15N5OS/c1-23-9-5-7-10(8-6-9)24-12-4-2-3-11-13(12)14-15(18)21-17(19)22-16(14)20-11/h2-8H,1H3,(H5,18,19,20,21,22)
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n/an/a 140n/an/an/an/an/an/a



Duquesne University

Curated by ChEMBL


Assay Description
Inhibition of human thymidylate synthase using dUMP/(6R,S)-tetrahydrofolate as substrate/co-factor by spectrophotometric method


Bioorg Med Chem Lett 27: 1602-1607 (2017)


Article DOI: 10.1016/j.bmcl.2017.02.018
BindingDB Entry DOI: 10.7270/Q2P55QR0
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50528948
PNG
(CHEMBL4451239)
Show SMILES Nc1nc2[nH]cc(Cc3ccc(cc3)C(=O)Nc3cc(ccc3CC(O)=O)C(O)=O)c2c(=O)[nH]1
Show InChI InChI=1S/C23H19N5O6/c24-23-27-19-18(21(32)28-23)15(10-25-19)7-11-1-3-12(4-2-11)20(31)26-16-8-14(22(33)34)6-5-13(16)9-17(29)30/h1-6,8,10H,7,9H2,(H,26,31)(H,29,30)(H,33,34)(H4,24,25,27,28,32)
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n/an/a 260n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometry


Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111673
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50528943
PNG
(CHEMBL4562561)
Show SMILES Nc1nc2[nH]cc(Cc3ccc(cc3)C(=O)Nc3cc(ccc3C(O)=O)C(O)=O)c2c(=O)[nH]1
Show InChI InChI=1S/C22H17N5O6/c23-22-26-17-16(19(29)27-22)13(9-24-17)7-10-1-3-11(4-2-10)18(28)25-15-8-12(20(30)31)5-6-14(15)21(32)33/h1-6,8-9H,7H2,(H,25,28)(H,30,31)(H,32,33)(H4,23,24,26,27,29)
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n/an/a 260n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometry


Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111673
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50009001
PNG
(5,6,7-Trihydroxyflavone | 5,6,7-trihydroxy-2-pheny...)
Show SMILES Oc1cc2oc(cc(=O)c2c(O)c1O)-c1ccccc1
Show InChI InChI=1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H
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n/an/a 260n/an/an/an/an/an/a



Institute for Bio-Medical Research

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes


J Med Chem 34: 1503-5 (1991)


Article DOI: 10.1021/jm00108a039
BindingDB Entry DOI: 10.7270/Q22Z14G6
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50011932
PNG
(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid ethy...)
Show SMILES CCOC(=O)C(=C\c1ccc(O)c(O)c1)\C#N
Show InChI InChI=1S/C12H11NO4/c1-2-17-12(16)9(7-13)5-8-3-4-10(14)11(15)6-8/h3-6,14-15H,2H2,1H3/b9-5+
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n/an/a 330n/an/an/an/an/an/a



Institute for Bio-Medical Research

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes


J Med Chem 34: 1503-5 (1991)


Article DOI: 10.1021/jm00108a039
BindingDB Entry DOI: 10.7270/Q22Z14G6
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50027655
PNG
(CHEBI:5847 | RALTITREXED | Raltitrexed | Tomudex |...)
Show SMILES CN(Cc1ccc2[nH]c(C)nc(=O)c2c1)c1ccc(s1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
Show InChI InChI=1S/C21H22N4O6S/c1-11-22-14-4-3-12(9-13(14)19(28)23-11)10-25(2)17-7-6-16(32-17)20(29)24-15(21(30)31)5-8-18(26)27/h3-4,6-7,9,15H,5,8,10H2,1-2H3,(H,24,29)(H,26,27)(H,30,31)(H,22,23,28)/t15-/m0/s1
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n/an/a 380n/an/an/an/an/an/a



Duquesne University

Curated by ChEMBL


Assay Description
Inhibition of human thymidylate synthase using dUMP/(6R,S)-tetrahydrofolate as substrate/co-factor by spectrophotometric method


Bioorg Med Chem Lett 27: 1602-1607 (2017)


Article DOI: 10.1016/j.bmcl.2017.02.018
BindingDB Entry DOI: 10.7270/Q2P55QR0
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50528946
PNG
(CHEMBL4459197)
Show SMILES COCc1ccc(C(O)=O)c(NC(=O)c2ccc(Cc3c[nH]c4nc(N)[nH]c(=O)c34)cc2)c1
Show InChI InChI=1S/C23H21N5O5/c1-33-11-13-4-7-16(22(31)32)17(9-13)26-20(29)14-5-2-12(3-6-14)8-15-10-25-19-18(15)21(30)28-23(24)27-19/h2-7,9-10H,8,11H2,1H3,(H,26,29)(H,31,32)(H4,24,25,27,28,30)
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n/an/a 390n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometry


Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111673
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50011934
PNG
(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid phen...)
Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCc2ccccc2)cc1O
Show InChI InChI=1S/C18H15NO4/c19-12-15(10-14-6-7-16(20)17(21)11-14)18(22)23-9-8-13-4-2-1-3-5-13/h1-7,10-11,20-21H,8-9H2/b15-10+
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n/an/a 430n/an/an/an/an/an/a



Institute for Bio-Medical Research

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes


J Med Chem 34: 1503-5 (1991)


Article DOI: 10.1021/jm00108a039
BindingDB Entry DOI: 10.7270/Q22Z14G6
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50512145
PNG
(CHEMBL4546953)
Show SMILES Clc1ccc(cc1)-n1cc(nn1)-c1cccc(NS(=O)(=O)c2c[nH]c(=O)[nH]c2=O)c1
Show InChI InChI=1S/C18H13ClN6O4S/c19-12-4-6-14(7-5-12)25-10-15(22-24-25)11-2-1-3-13(8-11)23-30(28,29)16-9-20-18(27)21-17(16)26/h1-10,23H,(H2,20,21,26,27)
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n/an/a 450n/an/an/an/an/an/a



China Medical University

Curated by ChEMBL


Assay Description
Inhibition of human thymidylate synthase using dUMP as substrate by spectrophotometric method


Eur J Med Chem 171: 282-296 (2019)


Article DOI: 10.1016/j.ejmech.2019.03.047
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50528945
PNG
(CHEMBL4565065)
Show SMILES Nc1nc2[nH]cc(Cc3ccc(cc3)C(=O)Nc3cc(ccc3C(O)=O)C#N)c2c(=O)[nH]1
Show InChI InChI=1S/C22H16N6O4/c23-9-12-3-6-15(21(31)32)16(8-12)26-19(29)13-4-1-11(2-5-13)7-14-10-25-18-17(14)20(30)28-22(24)27-18/h1-6,8,10H,7H2,(H,26,29)(H,31,32)(H4,24,25,27,28,30)
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n/an/a 460n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometry


Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111673
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50528940
PNG
(CHEMBL4544605)
Show SMILES Nc1nc2[nH]cc(Cc3ccc(cc3)C(=O)Nc3ccc(cc3)C(O)=O)c2c(=O)[nH]1
Show InChI InChI=1S/C21H17N5O4/c22-21-25-17-16(19(28)26-21)14(10-23-17)9-11-1-3-12(4-2-11)18(27)24-15-7-5-13(6-8-15)20(29)30/h1-8,10H,9H2,(H,24,27)(H,29,30)(H4,22,23,25,26,28)
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n/an/a 470n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometry


Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111673
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50235699
PNG
(CHEMBL4079829)
Show SMILES Nc1nc(N)c2c(n1)[nH]c1cccc(Sc3ccc(Cl)cc3)c21
Show InChI InChI=1S/C16H12ClN5S/c17-8-4-6-9(7-5-8)23-11-3-1-2-10-12(11)13-14(18)21-16(19)22-15(13)20-10/h1-7H,(H5,18,19,20,21,22)
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n/an/a 480n/an/an/an/an/an/a



Duquesne University

Curated by ChEMBL


Assay Description
Inhibition of human thymidylate synthase using dUMP/(6R,S)-tetrahydrofolate as substrate/co-factor by spectrophotometric method


Bioorg Med Chem Lett 27: 1602-1607 (2017)


Article DOI: 10.1016/j.bmcl.2017.02.018
BindingDB Entry DOI: 10.7270/Q2P55QR0
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50011938
PNG
(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-th...)
Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCc2cccs2)cc1O
Show InChI InChI=1S/C16H13NO4S/c17-10-12(8-11-3-4-14(18)15(19)9-11)16(20)21-6-5-13-2-1-7-22-13/h1-4,7-9,18-19H,5-6H2/b12-8+
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n/an/a 500n/an/an/an/an/an/a



Institute for Bio-Medical Research

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes


J Med Chem 34: 1503-5 (1991)


Article DOI: 10.1021/jm00108a039
BindingDB Entry DOI: 10.7270/Q22Z14G6
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50512143
PNG
(CHEMBL4587877)
Show SMILES Clc1cccc(c1)-n1cc(nn1)-c1cccc(NS(=O)(=O)c2c[nH]c(=O)[nH]c2=O)c1
Show InChI InChI=1S/C18H13ClN6O4S/c19-12-4-2-6-14(8-12)25-10-15(22-24-25)11-3-1-5-13(7-11)23-30(28,29)16-9-20-18(27)21-17(16)26/h1-10,23H,(H2,20,21,26,27)
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n/an/a 560n/an/an/an/an/an/a



China Medical University

Curated by ChEMBL


Assay Description
Inhibition of human thymidylate synthase using dUMP as substrate by spectrophotometric method


Eur J Med Chem 171: 282-296 (2019)


Article DOI: 10.1016/j.ejmech.2019.03.047
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50528958
PNG
(CHEMBL4476613)
Show SMILES COc1ccc(C(O)=O)c(NC(=O)c2ccc(Cc3c[nH]c4nc(N)[nH]c(=O)c34)cc2)c1
Show InChI InChI=1S/C22H19N5O5/c1-32-14-6-7-15(21(30)31)16(9-14)25-19(28)12-4-2-11(3-5-12)8-13-10-24-18-17(13)20(29)27-22(23)26-18/h2-7,9-10H,8H2,1H3,(H,25,28)(H,30,31)(H4,23,24,26,27,29)
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n/an/a 600n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometry


Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111673
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50512137
PNG
(CHEMBL4457367)
Show SMILES Clc1cccc(c1)-n1cc(nn1)-c1ccccc1NS(=O)(=O)c1c[nH]c(=O)[nH]c1=O
Show InChI InChI=1S/C18H13ClN6O4S/c19-11-4-3-5-12(8-11)25-10-15(22-24-25)13-6-1-2-7-14(13)23-30(28,29)16-9-20-18(27)21-17(16)26/h1-10,23H,(H2,20,21,26,27)
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n/an/a 600n/an/an/an/an/an/a



China Medical University

Curated by ChEMBL


Assay Description
Inhibition of human thymidylate synthase using dUMP as substrate by spectrophotometric method


Eur J Med Chem 171: 282-296 (2019)


Article DOI: 10.1016/j.ejmech.2019.03.047
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50528951
PNG
(CHEMBL4458803)
Show SMILES COc1ccc(NC(=O)c2ccc(Cc3c[nH]c4nc(N)[nH]c(=O)c34)cc2)c(c1)C(O)=O
Show InChI InChI=1S/C22H19N5O5/c1-32-14-6-7-16(15(9-14)21(30)31)25-19(28)12-4-2-11(3-5-12)8-13-10-24-18-17(13)20(29)27-22(23)26-18/h2-7,9-10H,8H2,1H3,(H,25,28)(H,30,31)(H4,23,24,26,27,29)
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n/an/a 700n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometry


Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111673
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50512136
PNG
(CHEMBL4460523)
Show SMILES Clc1ccc(cc1)-n1cc(nn1)-c1ccc(NS(=O)(=O)c2c[nH]c(=O)[nH]c2=O)cc1
Show InChI InChI=1S/C18H13ClN6O4S/c19-12-3-7-14(8-4-12)25-10-15(22-24-25)11-1-5-13(6-2-11)23-30(28,29)16-9-20-18(27)21-17(16)26/h1-10,23H,(H2,20,21,26,27)
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n/an/a 740n/an/an/an/an/an/a



China Medical University

Curated by ChEMBL


Assay Description
Inhibition of human thymidylate synthase using dUMP as substrate by spectrophotometric method


Eur J Med Chem 171: 282-296 (2019)


Article DOI: 10.1016/j.ejmech.2019.03.047
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50528947
PNG
(CHEMBL4445927)
Show SMILES COc1ccc(CC(O)=O)c(NC(=O)c2ccc(Cc3c[nH]c4nc(N)[nH]c(=O)c34)cc2)c1
Show InChI InChI=1S/C23H21N5O5/c1-33-16-7-6-14(9-18(29)30)17(10-16)26-21(31)13-4-2-12(3-5-13)8-15-11-25-20-19(15)22(32)28-23(24)27-20/h2-7,10-11H,8-9H2,1H3,(H,26,31)(H,29,30)(H4,24,25,27,28,32)
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n/an/a 800n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometry


Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111673
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50512142
PNG
(CHEMBL4543727)
Show SMILES Clc1ccccc1-n1cc(nn1)-c1ccccc1NS(=O)(=O)c1c[nH]c(=O)[nH]c1=O
Show InChI InChI=1S/C18H13ClN6O4S/c19-12-6-2-4-8-15(12)25-10-14(22-24-25)11-5-1-3-7-13(11)23-30(28,29)16-9-20-18(27)21-17(16)26/h1-10,23H,(H2,20,21,26,27)
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n/an/a 870n/an/an/an/an/an/a



China Medical University

Curated by ChEMBL


Assay Description
Inhibition of human thymidylate synthase using dUMP as substrate by spectrophotometric method


Eur J Med Chem 171: 282-296 (2019)


Article DOI: 10.1016/j.ejmech.2019.03.047
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50528950
PNG
(CHEMBL4454174)
Show SMILES NC(=O)c1ccc(C(O)=O)c(NC(=O)c2ccc(Cc3c[nH]c4nc(N)[nH]c(=O)c34)cc2)c1
Show InChI InChI=1S/C22H18N6O5/c23-17(29)12-5-6-14(21(32)33)15(8-12)26-19(30)11-3-1-10(2-4-11)7-13-9-25-18-16(13)20(31)28-22(24)27-18/h1-6,8-9H,7H2,(H2,23,29)(H,26,30)(H,32,33)(H4,24,25,27,28,31)
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n/an/a 1.00E+3n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometry


Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111673
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50235698
PNG
(CHEMBL4069070)
Show SMILES COc1ccc(OC)c(Sc2cccc3[nH]c4nc(N)nc(N)c4c23)c1
Show InChI InChI=1S/C18H17N5O2S/c1-24-9-6-7-11(25-2)13(8-9)26-12-5-3-4-10-14(12)15-16(19)22-18(20)23-17(15)21-10/h3-8H,1-2H3,(H5,19,20,21,22,23)
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n/an/a 1.10E+3n/an/an/an/an/an/a



Duquesne University

Curated by ChEMBL


Assay Description
Inhibition of human thymidylate synthase using dUMP/(6R,S)-tetrahydrofolate as substrate/co-factor by spectrophotometric method


Bioorg Med Chem Lett 27: 1602-1607 (2017)


Article DOI: 10.1016/j.bmcl.2017.02.018
BindingDB Entry DOI: 10.7270/Q2P55QR0
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50528955
PNG
(CHEMBL4445309)
Show SMILES Nc1nc2[nH]cc(Cc3ccc(cc3)C(=O)Nc3ccccc3-c3nnn[nH]3)c2c(=O)[nH]1
Show InChI InChI=1S/C21H17N9O2/c22-21-25-18-16(20(32)26-21)13(10-23-18)9-11-5-7-12(8-6-11)19(31)24-15-4-2-1-3-14(15)17-27-29-30-28-17/h1-8,10H,9H2,(H,24,31)(H,27,28,29,30)(H4,22,23,25,26,32)
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n/an/a 1.20E+3n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometry


Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111673
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50512139
PNG
(CHEMBL4458595)
Show SMILES Clc1ccccc1-n1cc(nn1)-c1cccc(NS(=O)(=O)c2c[nH]c(=O)[nH]c2=O)c1
Show InChI InChI=1S/C18H13ClN6O4S/c19-13-6-1-2-7-15(13)25-10-14(22-24-25)11-4-3-5-12(8-11)23-30(28,29)16-9-20-18(27)21-17(16)26/h1-10,23H,(H2,20,21,26,27)
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n/an/a 1.28E+3n/an/an/an/an/an/a



China Medical University

Curated by ChEMBL


Assay Description
Inhibition of human thymidylate synthase using dUMP as substrate by spectrophotometric method


Eur J Med Chem 171: 282-296 (2019)


Article DOI: 10.1016/j.ejmech.2019.03.047
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50528949
PNG
(CHEMBL4536417)
Show SMILES Nc1nc2[nH]cc(Cc3ccc(cc3)C(=O)Nc3ccccc3C(O)=O)c2c(=O)[nH]1
Show InChI InChI=1S/C21H17N5O4/c22-21-25-17-16(19(28)26-21)13(10-23-17)9-11-5-7-12(8-6-11)18(27)24-15-4-2-1-3-14(15)20(29)30/h1-8,10H,9H2,(H,24,27)(H,29,30)(H4,22,23,25,26,28)
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n/an/a 1.30E+3n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometry


Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111673
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50528957
PNG
(CHEMBL4570994)
Show SMILES Nc1nc2[nH]cc(Cc3ccc(cc3)C(=O)Nc3ccccc3C#N)c2c(=O)[nH]1
Show InChI InChI=1S/C21H16N6O2/c22-10-14-3-1-2-4-16(14)25-19(28)13-7-5-12(6-8-13)9-15-11-24-18-17(15)20(29)27-21(23)26-18/h1-8,11H,9H2,(H,25,28)(H4,23,24,26,27,29)
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n/an/a 1.30E+3n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometry


Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111673
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50011930
PNG
(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-ph...)
Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCCc2ccccc2)cc1O
Show InChI InChI=1S/C19H17NO4/c20-13-16(11-15-8-9-17(21)18(22)12-15)19(23)24-10-4-7-14-5-2-1-3-6-14/h1-3,5-6,8-9,11-12,21-22H,4,7,10H2/b16-11+
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n/an/a 1.40E+3n/an/an/an/an/an/a



Institute for Bio-Medical Research

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes


J Med Chem 34: 1503-5 (1991)


Article DOI: 10.1021/jm00108a039
BindingDB Entry DOI: 10.7270/Q22Z14G6
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50512146
PNG
(CHEMBL4459098)
Show SMILES Clc1cccc(c1)-n1cc(nn1)-c1ccc(NS(=O)(=O)c2c[nH]c(=O)[nH]c2=O)cc1
Show InChI InChI=1S/C18H13ClN6O4S/c19-12-2-1-3-14(8-12)25-10-15(22-24-25)11-4-6-13(7-5-11)23-30(28,29)16-9-20-18(27)21-17(16)26/h1-10,23H,(H2,20,21,26,27)
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n/an/a 1.58E+3n/an/an/an/an/an/a



China Medical University

Curated by ChEMBL


Assay Description
Inhibition of human thymidylate synthase using dUMP as substrate by spectrophotometric method


Eur J Med Chem 171: 282-296 (2019)


Article DOI: 10.1016/j.ejmech.2019.03.047
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50011935
PNG
(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-(2...)
Show SMILES COc1ccccc1CCOC(=O)C(=C\c1ccc(O)c(O)c1)\C#N
Show InChI InChI=1S/C19H17NO5/c1-24-18-5-3-2-4-14(18)8-9-25-19(23)15(12-20)10-13-6-7-16(21)17(22)11-13/h2-7,10-11,21-22H,8-9H2,1H3/b15-10+
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n/an/a 1.62E+3n/an/an/an/an/an/a



Institute for Bio-Medical Research

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes


J Med Chem 34: 1503-5 (1991)


Article DOI: 10.1021/jm00108a039
BindingDB Entry DOI: 10.7270/Q22Z14G6
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50512140
PNG
(CHEMBL4591608)
Show SMILES Clc1ccccc1-n1cc(nn1)-c1ccc(NS(=O)(=O)c2c[nH]c(=O)[nH]c2=O)cc1
Show InChI InChI=1S/C18H13ClN6O4S/c19-13-3-1-2-4-15(13)25-10-14(22-24-25)11-5-7-12(8-6-11)23-30(28,29)16-9-20-18(27)21-17(16)26/h1-10,23H,(H2,20,21,26,27)
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n/an/a 1.65E+3n/an/an/an/an/an/a



China Medical University

Curated by ChEMBL


Assay Description
Inhibition of human thymidylate synthase using dUMP as substrate by spectrophotometric method


Eur J Med Chem 171: 282-296 (2019)


Article DOI: 10.1016/j.ejmech.2019.03.047
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50528939
PNG
(CHEMBL4447254)
Show SMILES Nc1nc2[nH]cc(Cc3ccc(cc3)C(=O)Nc3ccccc3CC(O)=O)c2c(=O)[nH]1
Show InChI InChI=1S/C22H19N5O4/c23-22-26-19-18(21(31)27-22)15(11-24-19)9-12-5-7-13(8-6-12)20(30)25-16-4-2-1-3-14(16)10-17(28)29/h1-8,11H,9-10H2,(H,25,30)(H,28,29)(H4,23,24,26,27,31)
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n/an/a 1.70E+3n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometry


Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111673
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50528934
PNG
(CHEMBL4570248)
Show SMILES Nc1nc2[nH]cc(Cc3ccc(cc3)C(=O)NCc3ccccc3C(O)=O)c2c(=O)[nH]1
Show InChI InChI=1S/C22H19N5O4/c23-22-26-18-17(20(29)27-22)15(11-24-18)9-12-5-7-13(8-6-12)19(28)25-10-14-3-1-2-4-16(14)21(30)31/h1-8,11H,9-10H2,(H,25,28)(H,30,31)(H4,23,24,26,27,29)
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n/an/a 1.80E+3n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometry


Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111673
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50512144
PNG
(CHEMBL4463368)
Show SMILES Cc1cccc(c1)-n1cc(nn1)-c1ccccc1NS(=O)(=O)c1c[nH]c(=O)[nH]c1=O
Show InChI InChI=1S/C19H16N6O4S/c1-12-5-4-6-13(9-12)25-11-16(22-24-25)14-7-2-3-8-15(14)23-30(28,29)17-10-20-19(27)21-18(17)26/h2-11,23H,1H3,(H2,20,21,26,27)
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n/an/a 1.97E+3n/an/an/an/an/an/a



China Medical University

Curated by ChEMBL


Assay Description
Inhibition of human thymidylate synthase using dUMP as substrate by spectrophotometric method


Eur J Med Chem 171: 282-296 (2019)


Article DOI: 10.1016/j.ejmech.2019.03.047
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50512141
PNG
(Alimta | CHEBI:63722 | LY-231514 DISODIUM SALT | L...)
Show SMILES [Na+].[Na+].Nc1nc2[nH]cc(CCc3ccc(cc3)C(=O)N[C@@H](CCC([O-])=O)C([O-])=O)c2c(=O)[nH]1
Show InChI InChI=1S/C20H19N5O6.2Na/c21-20-24-16-15(18(29)25-20)12(9-22-16)6-3-10-1-4-11(5-2-10)17(28)23-13(19(30)31)7-8-14(26)27;;/h1-2,4-5,9,13H,3,6-8H2,(H,23,28)(H,26,27)(H,30,31)(H2,21,25,29);;/q;2*+1/p-2/t13-;;/m0../s1
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n/an/a 2.04E+3n/an/an/an/an/an/a



China Medical University

Curated by ChEMBL


Assay Description
Inhibition of human thymidylate synthase using dUMP as substrate by spectrophotometric method


Eur J Med Chem 171: 282-296 (2019)


Article DOI: 10.1016/j.ejmech.2019.03.047
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50528935
PNG
(CHEMBL4579109)
Show SMILES Nc1nc2[nH]cc(Cc3ccc(cc3)C(=O)Nc3cc(ccc3CC(O)=O)C#N)c2c(=O)[nH]1
Show InChI InChI=1S/C23H18N6O4/c24-10-13-3-6-15(9-18(30)31)17(8-13)27-21(32)14-4-1-12(2-5-14)7-16-11-26-20-19(16)22(33)29-23(25)28-20/h1-6,8,11H,7,9H2,(H,27,32)(H,30,31)(H4,25,26,28,29,33)
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n/an/a 2.20E+3n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometry


Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111673
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50235697
PNG
(CHEMBL4088617)
Show SMILES Nc1nc(N)c2c(n1)[nH]c1cccc(Sc3cccc4ccccc34)c21
Show InChI InChI=1S/C20H15N5S/c21-18-17-16-13(23-19(17)25-20(22)24-18)8-4-10-15(16)26-14-9-3-6-11-5-1-2-7-12(11)14/h1-10H,(H5,21,22,23,24,25)
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n/an/a 2.30E+3n/an/an/an/an/an/a



Duquesne University

Curated by ChEMBL


Assay Description
Inhibition of human thymidylate synthase using dUMP/(6R,S)-tetrahydrofolate as substrate/co-factor by spectrophotometric method


Bioorg Med Chem Lett 27: 1602-1607 (2017)


Article DOI: 10.1016/j.bmcl.2017.02.018
BindingDB Entry DOI: 10.7270/Q2P55QR0
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50528953
PNG
(CHEMBL4437270)
Show SMILES Nc1nc2[nH]cc(Cc3ccc(cc3)C(=O)Nc3cc(CO)ccc3C(O)=O)c2c(=O)[nH]1
Show InChI InChI=1S/C22H19N5O5/c23-22-26-18-17(20(30)27-22)14(9-24-18)7-11-1-4-13(5-2-11)19(29)25-16-8-12(10-28)3-6-15(16)21(31)32/h1-6,8-9,28H,7,10H2,(H,25,29)(H,31,32)(H4,23,24,26,27,30)
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n/an/a 2.80E+3n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometry


Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111673
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50528944
PNG
(CHEMBL4591345)
Show SMILES Nc1nc2[nH]cc(Cc3ccc(cc3)C(=O)Nc3cc(Cl)ccc3C(O)=O)c2c(=O)[nH]1
Show InChI InChI=1S/C21H16ClN5O4/c22-13-5-6-14(20(30)31)15(8-13)25-18(28)11-3-1-10(2-4-11)7-12-9-24-17-16(12)19(29)27-21(23)26-17/h1-6,8-9H,7H2,(H,25,28)(H,30,31)(H4,23,24,26,27,29)
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n/an/a 3.20E+3n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometry


Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111673
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50011931
PNG
((2E)‐3‐phenylprop‐2‐enR...)
Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OC\C=C\c2ccccc2)cc1O
Show InChI InChI=1S/C19H15NO4/c20-13-16(11-15-8-9-17(21)18(22)12-15)19(23)24-10-4-7-14-5-2-1-3-6-14/h1-9,11-12,21-22H,10H2/b7-4+,16-11+
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n/an/a 3.33E+3n/an/an/an/an/an/a



Institute for Bio-Medical Research

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes


J Med Chem 34: 1503-5 (1991)


Article DOI: 10.1021/jm00108a039
BindingDB Entry DOI: 10.7270/Q22Z14G6
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50528959
PNG
(CHEMBL4465849)
Show SMILES Nc1nc2[nH]cc(Cc3ccc(cc3)C(=O)Nc3ccccc3CCC(O)=O)c2c(=O)[nH]1
Show InChI InChI=1S/C23H21N5O4/c24-23-27-20-19(22(32)28-23)16(12-25-20)11-13-5-7-15(8-6-13)21(31)26-17-4-2-1-3-14(17)9-10-18(29)30/h1-8,12H,9-11H2,(H,26,31)(H,29,30)(H4,24,25,27,28,32)
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n/an/a 3.50E+3n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometry


Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111673
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50011933
PNG
(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 4-ph...)
Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCCCc2ccccc2)cc1O
Show InChI InChI=1S/C20H19NO4/c21-14-17(12-16-9-10-18(22)19(23)13-16)20(24)25-11-5-4-8-15-6-2-1-3-7-15/h1-3,6-7,9-10,12-13,22-23H,4-5,8,11H2/b17-12+
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n/an/a 3.59E+3n/an/an/an/an/an/a



Institute for Bio-Medical Research

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes


J Med Chem 34: 1503-5 (1991)


Article DOI: 10.1021/jm00108a039
BindingDB Entry DOI: 10.7270/Q22Z14G6
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50528942
PNG
(CHEMBL4442032)
Show SMILES Nc1nc2[nH]cc(Cc3ccc(cc3)C(=O)NC3CCCCC3C(O)=O)c2c(=O)[nH]1
Show InChI InChI=1S/C21H21N5O4/c22-21-25-17-16(19(28)26-21)13(10-23-17)9-11-5-7-12(8-6-11)18(27)24-15-4-2-1-3-14(15)20(29)30/h5-8,10,14-15H,1-4,9H2,(H,24,27)(H,29,30)(H2,22,26,28)
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n/an/a 3.80E+3n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometry


Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111673
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50011936
PNG
(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-py...)
Show SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCCc2cccnc2)cc1O
Show InChI InChI=1S/C18H16N2O4/c19-11-15(9-14-5-6-16(21)17(22)10-14)18(23)24-8-2-4-13-3-1-7-20-12-13/h1,3,5-7,9-10,12,21-22H,2,4,8H2/b15-9+
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n/an/a 3.93E+3n/an/an/an/an/an/a



Institute for Bio-Medical Research

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytes


J Med Chem 34: 1503-5 (1991)


Article DOI: 10.1021/jm00108a039
BindingDB Entry DOI: 10.7270/Q22Z14G6
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50528936
PNG
(CHEMBL4447274)
Show SMILES COCc1cccc(C(O)=O)c1NC(=O)c1ccc(Cc2c[nH]c3nc(N)[nH]c(=O)c23)cc1
Show InChI InChI=1S/C23H21N5O5/c1-33-11-14-3-2-4-16(22(31)32)18(14)26-20(29)13-7-5-12(6-8-13)9-15-10-25-19-17(15)21(30)28-23(24)27-19/h2-8,10H,9,11H2,1H3,(H,26,29)(H,31,32)(H4,24,25,27,28,30)
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n/an/a 6.00E+3n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometry


Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111673
More data for this
Ligand-Target Pair
Arachidonate 15-lipoxygenase, type II


(Rattus norvegicus)
BDBM50528938
PNG
(CHEMBL4551599)
Show SMILES Nc1nc2[nH]cc(Cc3ccc(\C=C\c4ccccc4C(O)=O)cc3)c2c(=O)[nH]1
Show InChI InChI=1S/C22H18N4O3/c23-22-25-19-18(20(27)26-22)16(12-24-19)11-14-7-5-13(6-8-14)9-10-15-3-1-2-4-17(15)21(28)29/h1-10,12H,11H2,(H,28,29)(H4,23,24,25,26,27)/b10-9+
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n/an/a 7.30E+3n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometry


Eur J Med Chem 183: (2019)


Article DOI: 10.1016/j.ejmech.2019.111673
More data for this
Ligand-Target Pair
15-Lipoxygenase-2 (15-LOX-2)


(Homo sapiens (Human))
BDBM50222277
PNG
(6,7-dihydroxy-3'-methylisoflavan | CHEMBL239893)
Show SMILES Cc1cccc(c1)C1COc2cc(O)c(O)cc2C1
Show InChI InChI=1S/C16H16O3/c1-10-3-2-4-11(5-10)13-6-12-7-14(17)15(18)8-16(12)19-9-13/h2-5,7-8,13,17-18H,6,9H2,1H3
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n/an/a 8.30E+3n/an/an/an/an/an/a



Universidad de Santiago de Chile

Curated by ChEMBL


Assay Description
Inhibition of 15-hLO2


Bioorg Med Chem 15: 7408-25 (2007)


Article DOI: 10.1016/j.bmc.2007.07.036
BindingDB Entry DOI: 10.7270/Q2RN37KN
More data for this
Ligand-Target Pair
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