BindingDB PrimarySearch

Found 2087 hits Enz. Inhib. hit(s) with Target = 'DRD1'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Adamed Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human recombinant D1 receptor expressed in CHO cells				J Med Chem 57: 4543-57 (2014) Article DOI: 10.1021/jm401895u BindingDB Entry DOI: 10.7270/Q2N29ZHX
Adamed Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Collegium Medicum Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in CHO cells				Eur J Med Chem 92: 221-35 (2015) Article DOI: 10.1016/j.ejmech.2014.12.045 BindingDB Entry DOI: 10.7270/Q2Q241XV
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Namur Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human dopamine D1 receptor				J Med Chem 54: 5320-34 (2011) Article DOI: 10.1021/jm2006782 BindingDB Entry DOI: 10.7270/Q2RF5W11
University of Namur Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine D1 receptor (Mus musculus (Mouse))	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 Show InChI	UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NOVO Industri A/S Curated by PDSP K_i Database									Eur J Pharmacol 146: 113-20 (1988) BindingDB Entry DOI: 10.7270/Q21R6P1H
NOVO Industri A/S Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by PDSP K_i Database									Proc Natl Acad Sci U S A 88: 7491-5 (1991) Article DOI: 10.1073/pnas.88.17.7491 BindingDB Entry DOI: 10.7270/Q2DB80B9
Duke University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of [3H]-SCH- 23390 binding to Dopamine receptor D1 from canine striatum				J Med Chem 35: 67-72 (1992) Article DOI: 10.1021/jm00079a008 BindingDB Entry DOI: 10.7270/Q2P84CHC
Northeastern University Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50306314 ((R)-N-(4-(7-chloro-8-hydroxy-3-methyl-2,3,4,5-tetr...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to dopamine D1 receptor				Bioorg Med Chem Lett 20: 836-40 (2010) Article DOI: 10.1016/j.bmcl.2009.12.100 BindingDB Entry DOI: 10.7270/Q23N23HT
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50306440 (11-chloro-12-hydroxy-7-methyl-6,6a,7,8,9,13b-hexah...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation counting				Bioorg Med Chem Lett 20: 832-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.094 BindingDB Entry DOI: 10.7270/Q2FX79JH
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50306442 ((6aS,13bS)-11-chloro-7-methyl-4-phenyl-6,6a,7,8,9,...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation counting				Bioorg Med Chem Lett 20: 832-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.094 BindingDB Entry DOI: 10.7270/Q2FX79JH
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50007550 (3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Binding affinity determined in radioreceptor binding assay by using [3H]-SCH-23,390 radioligand against dopamine receptor D1				J Med Chem 34: 1707-14 (1991) Article DOI: 10.1021/jm00109a026 BindingDB Entry DOI: 10.7270/Q2ZP4534
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50306452 ((6aS,13bS)-11-chloro-7-methyl-4-(pyridin-4-yl)-6,6...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation counting				Bioorg Med Chem Lett 20: 832-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.094 BindingDB Entry DOI: 10.7270/Q2FX79JH
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50010301 (8-Bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-be...) Show SMILES CN1CCc2cc(Br)c(O)cc2C(C1)c1ccccc1 Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP K_i Database									Nature 350: 614-9 (1991) Article DOI: 10.1038/350614a0 BindingDB Entry DOI: 10.7270/Q2NV9GQR
University of Toronto Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Binding affinity to displace [3H]- SCH 23390 against Dopamine receptor D1				J Med Chem 33: 2197-204 (1990) Article DOI: 10.1021/jm00170a025 BindingDB Entry DOI: 10.7270/Q2TD9XZB
Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Lund Curated by ChEMBL					Assay Description Compound was tested for the displacement of [3H]-SCH- 23390 from dopamine receptor D1				J Med Chem 35: 502-7 (1992) Article DOI: 10.1021/jm00081a010 BindingDB Entry DOI: 10.7270/Q2TH8N95
University of Lund Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50010301 (8-Bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-be...) Show SMILES CN1CCc2cc(Br)c(O)cc2C(C1)c1ccccc1 Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Binding affinity against dopamine receptor D1 by using [3H]-SCH- 23390 as radioligand in caudate-putamen of monkey				J Med Chem 34: 3235-41 (1991) Article DOI: 10.1021/jm00115a012 BindingDB Entry DOI: 10.7270/Q2KS6S5V
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine D1 receptor (Mus musculus (Mouse))	BDBM50026957 ((cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-yli...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar	Purchase PC cid PC sid UniChem Similars	PubMed	0.320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NOVO Industri A/S Curated by PDSP K_i Database									Eur J Pharmacol 146: 113-20 (1988) BindingDB Entry DOI: 10.7270/Q21R6P1H
NOVO Industri A/S Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50007551 (3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	0.330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Binding affinity determined in radioreceptor binding assay by using [3H]-SCH-23,390 radioligand against dopamine receptor D1				J Med Chem 34: 1707-14 (1991) Article DOI: 10.1021/jm00109a026 BindingDB Entry DOI: 10.7270/Q2ZP4534
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP K_i Database									Nature 350: 614-9 (1991) Article DOI: 10.1038/350614a0 BindingDB Entry DOI: 10.7270/Q2NV9GQR
University of Toronto Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50180913 (11-methyl-11-aza-tricyclo[12.4.0.0.3,8]octadeca-1(...) Show SMILES CN1CCc2ccccc2Cc2ccc(O)cc2CC1 Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.355	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universit£t Jena Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human cloned dopamine D1 receptor				Bioorg Med Chem Lett 18: 3809-13 (2008) Article DOI: 10.1016/j.bmcl.2008.04.081 BindingDB Entry DOI: 10.7270/Q23F4QWW
Friedrich-Schiller-Universit£t Jena Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50180913 (11-methyl-11-aza-tricyclo[12.4.0.0.3,8]octadeca-1(...) Show SMILES CN1CCc2ccccc2Cc2ccc(O)cc2CC1 Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Displacement of [3H]SCH 23390 from D1 dopamine receptor				J Med Chem 49: 2110-6 (2006) Article DOI: 10.1021/jm051237e BindingDB Entry DOI: 10.7270/Q2ZW1KHD
Friedrich-Schiller-Universität Jena Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50180913 (11-methyl-11-aza-tricyclo[12.4.0.0.3,8]octadeca-1(...) Show SMILES CN1CCc2ccccc2Cc2ccc(O)cc2CC1 Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Displacement of [3H]SCH 23390 from human cloned dopamine D1 receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 17: 1399-402 (2007) Article DOI: 10.1016/j.bmcl.2006.11.093 BindingDB Entry DOI: 10.7270/Q24T6J1G
Friedrich-Schiller-Universität Jena Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50180913 (11-methyl-11-aza-tricyclo[12.4.0.0.3,8]octadeca-1(...) Show SMILES CN1CCc2ccccc2Cc2ccc(O)cc2CC1 Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universit£t Jena Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in CHO cells by scintillation counting				Bioorg Med Chem 17: 6898-907 (2009) Article DOI: 10.1016/j.bmc.2009.08.028 BindingDB Entry DOI: 10.7270/Q2SB46P5
Friedrich-Schiller-Universit£t Jena Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50180913 (11-methyl-11-aza-tricyclo[12.4.0.0.3,8]octadeca-1(...) Show SMILES CN1CCc2ccccc2Cc2ccc(O)cc2CC1 Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of binding to human D1 receptor expressed in HEK 293 cells by radioligand binding assay				J Med Chem 49: 760-9 (2006) Article DOI: 10.1021/jm050846j BindingDB Entry DOI: 10.7270/Q22R3SF9
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50306443 ((6aS,13bS)-11-chloro-4-(3-fluorophenyl)-7-methyl-6...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation counting				Bioorg Med Chem Lett 20: 832-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.094 BindingDB Entry DOI: 10.7270/Q2FX79JH
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50010707 (8-Chloro-3-methyl-5-m-tolyl-2,3,4,5-tetrahydro-1H-...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Binding affinity to displace [3H]- SCH 23390 against Dopamine receptor D1				J Med Chem 33: 2197-204 (1990) Article DOI: 10.1021/jm00170a025 BindingDB Entry DOI: 10.7270/Q2TD9XZB
Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine D1 receptor (Mus musculus (Mouse))	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 Show InChI	UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Binding affinity to displace [3H]- SCH 23390 against Dopamine receptor D1				J Med Chem 33: 2197-204 (1990) Article DOI: 10.1021/jm00170a025 BindingDB Entry DOI: 10.7270/Q2TD9XZB
Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.427	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description In vitro inhibition of rat liver dihydrofolate reductase.				J Med Chem 32: 2050-8 (1989) Article DOI: 10.1021/jm00129a006
University of North Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50184428 (4-Chloro-3-hydroxy-7-methyl-5,6,7,8,9,14-hexahydro...) Show SMILES CN1CCc2ccccc2Cc2ccc(O)c(Cl)c2CC1 Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Inhibition of D1 dopamine receptor in HEK 293 cells by intracellular calcium assay				J Med Chem 49: 2110-6 (2006) Article DOI: 10.1021/jm051237e BindingDB Entry DOI: 10.7270/Q2ZW1KHD
Friedrich-Schiller-Universität Jena Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50184440 (1-Chloro-2-hydroxy-7-methyl-5,6,7,8,9,14-hexahydro...) Show SMILES CN1CCc2ccccc2Cc2c(CC1)ccc(O)c2Cl Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Displacement of [3H]SCH 23390 from D1 dopamine receptor				J Med Chem 49: 2110-6 (2006) Article DOI: 10.1021/jm051237e BindingDB Entry DOI: 10.7270/Q2ZW1KHD
Friedrich-Schiller-Universität Jena Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50306322 (CHEMBL597909 \| N-((6aS,13bR)-11-chloro-12-hydroxy-...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to dopamine D1 receptor				Bioorg Med Chem Lett 20: 836-40 (2010) Article DOI: 10.1016/j.bmcl.2009.12.100 BindingDB Entry DOI: 10.7270/Q23N23HT
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50306316 ((R)-N-(4-(7-chloro-8-hydroxy-3-methyl-2,3,4,5-tetr...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to dopamine D1 receptor				Bioorg Med Chem Lett 20: 836-40 (2010) Article DOI: 10.1016/j.bmcl.2009.12.100 BindingDB Entry DOI: 10.7270/Q23N23HT
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50306315 ((R)-N-(4-(7-chloro-8-hydroxy-3-methyl-2,3,4,5-tetr...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to dopamine D1 receptor				Bioorg Med Chem Lett 20: 836-40 (2010) Article DOI: 10.1016/j.bmcl.2009.12.100 BindingDB Entry DOI: 10.7270/Q23N23HT
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50201338 (7-methyl-6,7,8,9,14,15-hexahydro-5H-indolo[3,2-f][...) Show SMILES CN1CCc2c(Cc3ccccc3CC1)[nH]c1ccc(O)cc21 Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Displacement of [3H]SCH 23390 from human cloned dopamine D1 receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 17: 1399-402 (2007) Article DOI: 10.1016/j.bmcl.2006.11.093 BindingDB Entry DOI: 10.7270/Q24T6J1G
Friedrich-Schiller-Universität Jena Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50201338 (7-methyl-6,7,8,9,14,15-hexahydro-5H-indolo[3,2-f][...) Show SMILES CN1CCc2c(Cc3ccccc3CC1)[nH]c1ccc(O)cc21 Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.562	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universit£t Jena Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human cloned dopamine D1 receptor				Bioorg Med Chem Lett 18: 3809-13 (2008) Article DOI: 10.1016/j.bmcl.2008.04.081 BindingDB Entry DOI: 10.7270/Q23F4QWW
Friedrich-Schiller-Universit£t Jena Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM160878 (US10093655, Example 48 \| US9107923, 48) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	PC cid PC sid UniChem	US Patent	0.571	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Pfizer Inc. US Patent					Assay Description The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...				US Patent US10093655 (2018)
Pfizer Inc. US Patent					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM160878 (US10093655, Example 48 \| US9107923, 48) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	PC cid PC sid UniChem	US Patent	0.571	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., Dif...				US Patent US9107923 (2015) BindingDB Entry DOI: 10.7270/Q2C24V5T
Pfizer Inc. US Patent					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50368313 (CHEMBL1744079) Show SMILES CN1CCc2cc(Br)c(O)cc2[C@H](C1)c1ccccc1 Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of [3H]-SCH- 23390 binding to Dopamine receptor D1 from canine striatum				J Med Chem 35: 67-72 (1992) Article DOI: 10.1021/jm00079a008 BindingDB Entry DOI: 10.7270/Q2P84CHC
Northeastern University Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50306453 ((6aS,13bS)-11-chloro-4-(1H-indol-5-yl)-7-methyl-6,...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation counting				Bioorg Med Chem Lett 20: 832-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.094 BindingDB Entry DOI: 10.7270/Q2FX79JH
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50306435 ((6aS,13bS)-11-chloro-7-methyl-6,6a,7,8,9,13b-hexah...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation counting				Bioorg Med Chem Lett 20: 832-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.094 BindingDB Entry DOI: 10.7270/Q2FX79JH
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50306444 (3-((6aS,13bS)-11-chloro-12-hydroxy-7-methyl-6,6a,7...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation counting				Bioorg Med Chem Lett 20: 832-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.094 BindingDB Entry DOI: 10.7270/Q2FX79JH
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50306445 ((6aS,13bS)-11-chloro-7-methyl-4-(3-nitrophenyl)-6,...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation counting				Bioorg Med Chem Lett 20: 832-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.094 BindingDB Entry DOI: 10.7270/Q2FX79JH
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50306317 ((R)-N-(4-(7-chloro-8-hydroxy-3-methyl-2,3,4,5-tetr...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to dopamine D1 receptor				Bioorg Med Chem Lett 20: 836-40 (2010) Article DOI: 10.1016/j.bmcl.2009.12.100 BindingDB Entry DOI: 10.7270/Q23N23HT
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM81490 (CAS_60197-32-2 \| CIS PIFLUTIXOL \| NSC_68714 \| Pifl...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	0.650	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by PDSP K_i Database									Proc Natl Acad Sci U S A 88: 7491-5 (1991) Article DOI: 10.1073/pnas.88.17.7491 BindingDB Entry DOI: 10.7270/Q2DB80B9
Duke University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50306325 (1-((6aS,13bR)-11-chloro-12-hydroxy-7-methyl-6,6a,7...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to dopamine D1 receptor				Bioorg Med Chem Lett 20: 836-40 (2010) Article DOI: 10.1016/j.bmcl.2009.12.100 BindingDB Entry DOI: 10.7270/Q23N23HT
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50306319 ((R)-5-(4-((benzyl(2,4-difluorophenyl)amino)methyl)...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to dopamine D1 receptor				Bioorg Med Chem Lett 20: 836-40 (2010) Article DOI: 10.1016/j.bmcl.2009.12.100 BindingDB Entry DOI: 10.7270/Q23N23HT
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50306448 ((6aS,13bS)-11-chloro-4-(4-methoxyphenyl)-7-methyl-...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation counting				Bioorg Med Chem Lett 20: 832-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.094 BindingDB Entry DOI: 10.7270/Q2FX79JH
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50306449 ((6aS,13bS)-11-chloro-4-(4-(dimethylamino)phenyl)-7...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation counting				Bioorg Med Chem Lett 20: 832-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.094 BindingDB Entry DOI: 10.7270/Q2FX79JH
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50306450 ((6aS,13bS)-11-chloro-4-(4-(hydroxymethyl)phenyl)-7...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation counting				Bioorg Med Chem Lett 20: 832-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.094 BindingDB Entry DOI: 10.7270/Q2FX79JH
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50306323 (CHEMBL600986 \| N-((6aS,13bR)-11-chloro-12-hydroxy-...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to dopamine D1 receptor				Bioorg Med Chem Lett 20: 836-40 (2010) Article DOI: 10.1016/j.bmcl.2009.12.100 BindingDB Entry DOI: 10.7270/Q23N23HT
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK293 cells				Bioorg Med Chem 16: 6675-81 (2008) Article DOI: 10.1016/j.bmc.2008.05.077 BindingDB Entry DOI: 10.7270/Q2SB45KD
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair

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